Abstract: The invention may be embodied in other forms than those specifically disclosed herein without departing from itMulti-kW-class blue (400-495 nm) fiber-delivered lasers and module configurations. In embodiments, the lasers propagate laser beams having beam parameter products of <5 mm*mrad, which are used in materials processing, welding and pumping a Raman laser. In an embodiment the laser system is an integration of fiber-coupled modules, which are in turn made up of submodules. An embodiment has sub-modules having a plurality of lensed blue semiconductor gain chips with low reflectivity front facets. These are locked in wavelength with a wavelength spread of <1 nm by using volume Bragg gratings in an external cavity configuration. An embodiment has modules having of a plurality of submodules, which are combined through wavelength multiplexing with a bandwidth of <10 nm, followed by polarization beam combining. The output of each module is fiber-coupled into a low NA fiber.

Abstract: A valve actuation system comprises a first arm having a first arm contact surface and operatively connected to a valve actuation motion. A second arm having a second arm contact surface is operatively connected to the at least one engine valve. A discrete lost motion device is provided that is controllable between a first, motion conveying state and a second, motion absorbing state. The discrete lost motion devices comprises a plunger contact surface and a housing contact surface. The housing contact surface is configured to engage one of the first or second arm contact surfaces, and the plunger contact surface is configured to engage another of the first and the second arm contact surfaces. The first and second arm contact surfaces, the housing contact surface and the first plunger contact surface are configured to support the discrete lost motion device between the first arm and the second arm.

Abstract: Disclosed herein are compounds of Formula (I), or pharmaceutically acceptable salts thereof, that are inhibitors of Polo Like Kinase 4 (PLK4). Also disclosed herein are pharmaceutical compositions comprising the compounds of Formula (I), or pharmaceutically acceptable salts thereof, and one or more pharmaceutically acceptable excipients. Further disclosed herein are methods of treating cancer in a subject in need thereof, comprising administering to the subject an amount of a compound of Formula (I), or a pharmaceutically acceptable salt thereof.

Abstract: A discrete lost motion device for use in a valve train of an internal combustion engine comprises a housing having a housing bore extending longitudinally into the housing and a second end having a housing contact surface configured to engage a corresponding contact surface of a first valve train component. A plunger slidably is disposed in the housing bore is controllable between a first state in which the plunger rigidly extends out of the housing bore and a second state in which the plunger is permitted to reciprocate within the housing bore, the plunger further comprising an end having a plunger contact surface configured to engage a corresponding contact surface of a second valve train component. The housing contact surface and the plunger contact surface are configured to support the discrete lost motion device between the first and second valve train components.

Abstract: A ventilator having a functionality to defrost a ventilator core includes a two sets of ports, one set used for coupling of the ventilator with ducting and other used for redirecting indoor air flowing along a first flowpath through the recovery core to a second flow path normally used for outdoor air. A re-circulator is removably fixed between an inlet for outdoor air and an outlet for indoor air of the set of ports not coupled to the ducting. A pair of dampers, operated by a single motor, allow the ventilator to be operated in a mode that enables redirection of the indoor air from the first flowpath to the second flowpath, simultaneously blocking inflow of the outdoor air.

Abstract: Systems, method sand computer readable medium are provided for proving real-time Self Optimizing Network (SON) Virtual Network Function (VRF) included as part of the HNG. In one embodiment data from connected devices is forwarded to the HNG; the data is organized into virtualized containers; and the data is processed by agile analytics and results are displayed to a user.

Abstract: A turbine engine having a compressor section, a combustor section, a turbine section, and a rotatable drive shaft that couples a portion of the turbine section and a portion of the compressor section. A bypass conduit couples the compressor section to the turbine section while bypassing at least the combustion section. At least one particle separator is located in the turbine engine having a separator inlet that receives a bypass stream, a separator outlet that receives a reduced-particle stream flows, and a particle outlet that receives a concentrated-particle stream comprising separated particles. A conduit, fluidly coupled to the particle outlet, extends through an interior of at least one stationary vane.

Abstract: The invention provides novel methods for preparing indolinobenzodiazepine monomer compounds and their synthetic precursors.

Abstract: The present invention relates to antibodies binding to IL13 and IL22. The invention provides novel multi-specific antibodies that bind to both IL13 and IL22 and compositions comprising an antibody that binds to IL13 and an antibody that binds to IL22. The invention further relates to therapeutic uses of the combination of anti-IL13 and anti-IL22 antibodies and multi-specific antibodies that bind to both IL13 and IL22.

Abstract: A multi-functional, portable device for use in situations where electricity is not available or convenient is disclosed. A portable safety device includes a power charger and air compressor that may safely jump start a vehicle and recharge portable electronic devices, such as phones and laptop computers, as well as inflate vehicle tires or other inflatable objects, when a standard external power source is not convenient. It may also be used for providing an emergency light source.

Abstract: A ventilator includes a housing having at least one opening formed therein. The housing has a plurality of sides including a first side and a second side and a modular duct connector having a through hole for connection with a duct. The modular duct connector is connectable to the at least one opening of the housing in at least a first configuration and a second configuration. In the first configuration, the through hole is arranged at the first side of the housing and in the second configuration, the through hole is arranged at the second side of the housing.

Abstract: A dividing wall column system is provided. The dividing wall column system comprises a dividing wall column, a first reboiler, a second reboiler, and a heat pump. The dividing wall column includes a dividing wall positioned in a bottom section of the dividing wall column to divide the bottom section of the dividing wall column into a first side and a second side. The first reboiler is outside of the dividing wall column and in fluid communication with the first side of the bottom section of the dividing wall column. The second reboiler is outside of the dividing wall column and in fluid communication with the second side of the bottom section of the dividing wall column. The heat pump is in fluid communication with the dividing wall column and the second reboiler and configured to compress a first portion of an overhead product from the dividing wall column.

Abstract: A method, apparatus, computer readable medium for maintaining a user profile at a web service, including receiving at least one search term from a mobile application, generating a profile associated with an identifier for the mobile application, and storing the received at least one search term from the mobile application in connection with the identifier in the profile. The web service may generate an anonymous identifier for the mobile application, wherein the at least one search term from the mobile application is stored in connection with the anonymous identifier in the profile. The web service may receive and store a location and other information from the mobile application. The profile may be updated so that additional searches can be performed based at least in part of the maintained profile.

Abstract: A communication system may be provided that includes a lead communication assembly configured to be disposed onboard a lead vehicle in a multi-vehicle system, and a remote communication assembly configured to be disposed onboard a remote vehicle in the multi-vehicle system. The lead communication assembly and the remote communication assembly may be configured to communicate with each other via a wired connection extending along the multi-vehicle system from at least the lead vehicle to at least the remote vehicle. Additionally, the lead communication assembly and the remote communication assembly may also be configured to communicate with each other via a wireless connection. The lead communication assembly and the remote communication assembly may also be configured to switch back-and-forth between communicating with each other via the wired connection and via the wireless connection.

Abstract: Systems, method sand computer readable medium are provided for proving real-time Self Optimizing Network (SON) Virtual Network Function (VRF) included as part of the HNG. In one embodiment data from connected devices is forwarded to the HNG; the data is organized into virtualized containers; and the data is processed by agile analytics and results are displayed to a user.

Abstract: Concepts and technologies are disclosed herein for extracting and redacting sensitive information from audio. A call having audio and being associated with a customer can be received at a computing device, and the call can be routed to an agent device. During the call, the computing device can detect an impending disclosure of sensitive personal information of the customer. The computing device can generate, during the call, sensitive data that can correspond to the sensitive personal information. The sensitive data can be generated based on sensitive audio of the call. The computing device can provide modified audio to the agent device in real-time or non-real-time. The modified audio can include nonsensitive audio of the call and can omit the sensitive audio. The sensitive data can be provided to a call handling application that is in communication with the computing device and with the agent device.

Abstract: A multi-functional, portable device for use in situations where electricity is not available or convenient is disclosed. A portable safety device includes a power charger and air compressor that may safely jump start a vehicle and recharge portable electronic devices, such as phones and laptop computers, as well as inflate vehicle tires or other inflatable objects, when a standard external power source is not convenient. It may also be used for providing an emergency light source.

Abstract: Systems, method sand computer readable medium are provided for proving real-time Self Optimizing Network (SON) Virtual Network Function (VRF) included as part of the HNG. In one embodiment data from connected devices is forwarded to the HNG; the data is organized into virtualized containers; and the data is processed by agile analytics and results are displayed to a user.

Abstract: Systems, methods, and apparatuses are provided for securely receiving packages or items from a delivery service and stopping porch pirates from stealing the packages or items. A single door or multi-door embodiment selectively allows access to a lockable box so that a delivery service can place packages or items in the lockable box that a purchaser can later retrieve. The lockable box can have a locking system with rotatable key combinations, temporary key combinations, and/or other features that allow a delivery service to selectively access the lockable box. Some embodiments also integrate the lockable box into existing features of a residence such as a door.