Patents by Inventor Michael Simons

Michael Simons has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20060200853
    Abstract: Systems, methods, apparatus and computer program products are provided for signaling to a receiver an availability of a service and a deterministic mapping of a service content corresponding to the service. A modulator receives a digital signal and generates a data frame from the digital signal, where the data frame is divided into segments, where at least one grouping of the segments contains the service content. The modulator modulates at least one grouping in accordance with the deterministic mapping. A receiving device receives a digital signal containing the availability of a service, the deterministic mapping corresponding to the service, and the service content, and performs an operation on the service content in accordance with the deterministic mapping.
    Type: Application
    Filed: March 1, 2006
    Publication date: September 7, 2006
    Applicant: Rohde & Schwarz, Inc.
    Inventor: Michael Simon
  • Publication number: 20060136314
    Abstract: A method for preventing disablement of a device includes assigning a contract identification code, receiving a loan payment, forwarding the loan payment from a payment center to a finance company having an interest in the device, a code delivery computer determining whether the finance company has received the payment, the code delivery computer determining a previous code released for the device, releasing a new code subsequent to the previous code released for the device if the code delivery computer determines that the finance company has received the payment, the code delivery computer receiving the associated contract identification code from a user via telephony or an internet link, the code delivery computer providing the new code directly to the user via telephony, an internet link, or an email, and the device receiving the code from the user, thereby preventing disablement of the device.
    Type: Application
    Filed: August 18, 2005
    Publication date: June 22, 2006
    Applicant: Payment Protection Systems, Inc.
    Inventor: Michael Simon
  • Publication number: 20060108417
    Abstract: An exemplary appliance control system for controlling an appliance includes a controller located inside the appliance, wherein the controller comprises a switch arranged between the electric power source and the appliance power supply and a receiver, a payment control center, and a payment control module comprising a transmitter for communicating with the controller receiver and a modem for communicating with the payment control center via a communication network. Another exemplary appliance control system includes a switch located between an electrical power source and an electrical power socket that provides electrical power to the appliance, a payment control center, and a payment control module that communicates with the switch and the payment control center, wherein the payment control module instructs the switch to open when the payment control center indicates that a finance payment for the appliance is past due.
    Type: Application
    Filed: October 25, 2005
    Publication date: May 25, 2006
    Applicant: Payment Protection Systems, Inc.
    Inventors: Franklin Simon, Michael Simon
  • Publication number: 20060084114
    Abstract: The present invention relates to a method of detecting collateral artery formation by measuring the level of NT-pro-BNP or BNP in an individual.
    Type: Application
    Filed: October 15, 2004
    Publication date: April 20, 2006
    Inventors: Kiang-Tech Yeo, Michael Simons
  • Patent number: 7029668
    Abstract: The present invention provides tangible means and methods for stimulation of angiogenesis via enhanced endothelial expression of core proteins having a syndecan-4 cytoplasmic region intracellularly. The tangible means include a prepared DNA sequence fragment having separate and individual DNA sequenced portions coding for an heparan sulfate binding extracellular domain, a central transmembrane domain, and a cytoplasmic domain coding for the syndecan-4 polypeptide. The prepared DNA sequence unitary fragment may be delivered to endothelial cells in-situ, both under in-vivo and/or in-vitro conditions, using suitable expression vectors including plasmids and viruses. The resulting transfected endothelial cells overexpress heparan sulfate binding, core proteins; and the resulting overexpression of these proteoglycan entities causes stimulation of angiogenesis in-situ.
    Type: Grant
    Filed: January 28, 2003
    Date of Patent: April 18, 2006
    Assignee: Beth Israel Deaconess Medical Center
    Inventors: Michael Simons, Ruediger Volk, Arie Horowitz
  • Publication number: 20060030003
    Abstract: A composition and method are provided by which double-stranded RNA containing small interfering RNA nucleotide sequences is introduced into specific cells and tissues for the purpose of inhibiting gene expression and protein production in those cells and tissues. Intracellular introduction of the small interfering RNA nucleotide sequences is accomplished by the internalization of a target cell specific ligand bonded to a RNA binding protein to which a double-stranded RNA containing a small interfering RNA nucleotide sequence is adsorbed. The ligand is specific to a unique target cell surface antigen. The ligand is either spontaneously internalized after binding to the cell surface antigen.
    Type: Application
    Filed: July 21, 2005
    Publication date: February 9, 2006
    Inventor: Michael Simon
  • Publication number: 20050260214
    Abstract: A composition and method are provided by which double-stranded RNA containing small interfering RNA nucleotide sequences is introduced into specific cells and tissues for the purpose of inhibiting gene expression and protein production in those cells and tissues. Intracellular introduction of the small interfering RNA nucleotide sequences is accomplished by the internalization of a target cell specific ligand to which the double-stranded RNA containing a small interfering RNA nucleotide sequence is conjugated. The ligand is specific to a unique target cell surface antigen. The ligand is either spontaneously internalized after binding to the cell surface antigen. Internalization is also facilitated by the binding of an RNA binding protein to the double-stranded RNA.
    Type: Application
    Filed: May 11, 2005
    Publication date: November 24, 2005
    Inventor: Michael Simon
  • Publication number: 20050255120
    Abstract: Double-stranded DNA which encodes for a promoter region and for small interfering RNA nucleotide sequences is introduced into specific cells and tissues for the purpose of inhibiting gene expression and protein production in those cells and tissues. Intracellular introduction of the small interfering RNA nucleotide sequences is accomplished by the internalization of a target cell specific ligand bonded to the double-stranded DNA which encodes for a promoter region and for a small interfering RNA nucleotide sequence. The ligand is spontaneously internalized after binding to the cell surface antigen. Optionally, internalization is also facilitated by the binding of a DNA binding protein to the double-stranded DNA. If the unique cell surface antigen is not naturally internalized after binding to its ligand, internalization is promoted by the incorporation of an internalization moiety into the structure of the ligand or attachment of such a peptide to the ligand.
    Type: Application
    Filed: May 11, 2005
    Publication date: November 17, 2005
    Inventor: Michael Simon
  • Publication number: 20050239000
    Abstract: The invention relates to a method for the preparation of a printing plate comprises forming an oleophilic image on a substrate for a printing plate comprising a support having at least one hydrophilic layer on its surface, the oleophilic image being formed by inkjet printing an aqueous solution or aqueous colloidal dispersion of an anionic oleophilising agent on the surface of the support and drying the applied solution or dispersion, such that, on drying, the area of the surface to which the solution or dispersion was applied becomes lithographic ink-accepting, characterised in that the hydrophilic layer comprises a crosslinked cationic polymer. The invention further relates to a substrate for a printing plate comprising a support having at least one hydrophilic layer on its surface wherein the hydrophilic layer comprises a crosslinked cationic polymer.
    Type: Application
    Filed: June 29, 2005
    Publication date: October 27, 2005
    Inventor: Michael Simons
  • Publication number: 20050162016
    Abstract: A user interface for a vehicle disablement system is provided. The user interface provides an indication of an amount of time remaining prior to disablement of the vehicle. The indication can be performed using a light emitting diode (LED) which produces either a red or green light. The indication can also be performed by an LED producing a number of blinks corresponding to the amount of time remaining prior to disablement of the vehicle. Additional LEDs can be provided within a numbered user interface, for example, wherein an LED of a number on the user interface is illuminated corresponding to an amount of time remaining prior to disablement of the vehicle.
    Type: Application
    Filed: October 6, 2004
    Publication date: July 28, 2005
    Applicant: Payment Protection Systems, Inc.
    Inventor: Michael Simon
  • Publication number: 20050134438
    Abstract: A vehicle disablement device detects whether it has been tampered with. If the vehicle disablement device determines that it has been tampered with, the vehicle disablement device sends a signal to a tamper disabler. The tamper disabler is then able to disable the vehicle in the same manner in which the vehicle disablement device disables the vehicle. Accordingly, the vehicle may be disabled even when the vehicle disablement device is tampered with.
    Type: Application
    Filed: January 12, 2005
    Publication date: June 23, 2005
    Applicant: Payment Protection Systems, Inc.
    Inventor: Michael Simon
  • Publication number: 20050076370
    Abstract: A real time apparatus for testing a DTV antenna transmitting system, wherein the DTV antenna transmitting system transmits an original signal from a DTV transmitter to a DTV transmitting antenna, is disclosed that includes a probe, wherein the probe is connected in series with the DTV antenna transmitting system, and senses signals traversing the DTV antenna transmitting system. An error detector of the testing apparatus compares the received signal to the original signal to identify the magnitude and location of errors.
    Type: Application
    Filed: June 10, 2004
    Publication date: April 7, 2005
    Inventors: Michael Simon, Andre Skalina
  • Publication number: 20050033483
    Abstract: A vehicle disablement device disables a vehicle if it a payment has not been received prior to a payment due deadline. The vehicle can also be disabled if it is determined that the vehicle disablement device is being tampered with. Disablement of the vehicle occurs by transmission of a wireless signal from a vehicle disablement device to a relay in a power control panel. The disablement can also occur by transmission of a second wireless signal from a tamper disabler (or a tamper receiver) to a relay in the power control panel. The critical system of the vehicle that can be disabled by the vehicle disablement device can be the same or a different critical system as that which can be disabled by the tamper disabler (or a tamper receiver).
    Type: Application
    Filed: July 8, 2004
    Publication date: February 10, 2005
    Inventors: Michael Simon, Franklin Simon
  • Patent number: 6852515
    Abstract: The present invention provides tangible means and methods for stimulation of angiogenesis via enhanced endothelial expression of core proteins having a syndecan-4 cytoplasmic region intracellularly. The tangible means include a prepared DNA sequence fragment having separate and individual DNA sequenced portions coding for an heparan sulfate binding extracellular domain, a central transmembrane domain, and a cytoplasmic domain coding for the syndecan-4 polypeptide. The prepared DNA sequence unitary fragment may be delivered to endothelial cells in-situ, both under in-vivo and/or in-vitro conditions, using suitable expression vectors including plasmids and viruses. The resulting transfected endothelial cells overexpress heparan sulfate binding, core proteins; and the resulting overexpression of these proteoglycan entities causes stimulation of angiogenesis in-situ.
    Type: Grant
    Filed: September 2, 1998
    Date of Patent: February 8, 2005
    Assignee: Beth Israel Deaconess Medical Center
    Inventors: Michael Simons, Rudiger Volk, Arie Horowitz
  • Patent number: 6815187
    Abstract: The present invention provides a methodology and compositions for stimulating angiogenesis in-situ within viable cells, tissues and organs comprising endothelial cells. The methodology focuses upon and controls the phosphorylation of the 183rd amino acid residue, serine, within the cytoplasmic domain and intracellular tail of transmembrane syndecan-4 proteoglycans which are then positioned at and through the cellular membrane of viable endothelial cells. By intervening and maintaining the 183rd residue in a non-phosphorylated state, a consequential cascade of intracellular events is initiated which result in a stimulation of angiogenesis in-situ.
    Type: Grant
    Filed: November 12, 1998
    Date of Patent: November 9, 2004
    Assignee: Beth Israel Deaconess Medical Center
    Inventors: Michael Simons, Arie Horowitz
  • Publication number: 20040172931
    Abstract: A cutting device for plants, particularly lawnmower, is provided with at least one rotating blade (4a), which cooperates with a stationary counter-blade (13a). Here, at least the blade (4a) and/or the counter-blade (13a) is replaceably arranged in a respective blade support (3a, 14a).
    Type: Application
    Filed: July 30, 2003
    Publication date: September 9, 2004
    Applicant: WOLF-Gerate AG
    Inventors: Walter Kolb, Michael Simon
  • Publication number: 20040087654
    Abstract: A compound of formula (I): namely (2S)-2-amino-4-{[2-(etha-nimidoylamino)ethyl]thio}butanoic acid, compound with prosphoric acid, or a solvate or physiologically functional derivative thereof, is useful as a relatively non-hygroscopic selective inhibitor of inducible nitric oxice synthase.
    Type: Application
    Filed: November 11, 2003
    Publication date: May 6, 2004
    Inventors: David Box, David Colclough, Iain Gillies, Michael Simon Loft, Rebecca Moore
  • Publication number: 20040072263
    Abstract: Custom-engineered glucose oxidase fusion proteins, prepared by recombinant DNA techniques, are employed in a chip-based amperometric immunosensor. This on-chip assay provides quantitative measurement of analyte concentration in any fluid, including all body fluids. The system is designed to facilitate ease in swapping of molecular recognition components and can be rapidly adapted to measure the concentration of any peptide or protein for which a monoclonal antibody is available.
    Type: Application
    Filed: April 21, 2003
    Publication date: April 15, 2004
    Applicant: Baylor College of Medicine
    Inventors: Richard E. Link, Ronald A. Morton, Brian Miles, Michael Simon
  • Publication number: 20040053425
    Abstract: Custom-engineered glucose oxidase fusion proteins, prepared by recombinant DNA techniques, are employed in a chip-based amperometric immunosensor. This on-chip assay provides quantitative measurement of analyte concentration in any fluid, including all body fluids. The system is designed to facilitate ease in swapping of molecular recognition components and can be rapidly adapted to measure the concentration of any peptide or protein for which a monoclonal antibody is available.
    Type: Application
    Filed: May 6, 2003
    Publication date: March 18, 2004
    Applicant: Baylor College of Medicine
    Inventors: Richard E. Link, Ronald A. Morton, Brian Miles, Michael Simon
  • Publication number: 20040013653
    Abstract: The present invention provides tangible means and methods for stimulation of angiogenesis via enhanced endothelial expression of core proteins having a syndecan-4 cytoplasmic region intracellularly. The tangible means include a prepared DNA sequence fragment having separate and individual DNA sequenced portions coding for an heparan sulfate binding extracellular domain, a central transmembrane domain, and a cytoplasmic domain coding for the syndecan-4 polypeptide. The prepared DNA sequence unitary fragment may be delivered to endothelial cells in-situ, both under in-vivo and/or in-vitro conditions, using suitable expression vectors including plasmids and viruses. The resulting transfected endothelial cells overexpress heparan sulfate binding, core proteins; and the resulting overexpression of these proteoglycan entities causes stimulation of angiogenesis in-situ.
    Type: Application
    Filed: January 28, 2003
    Publication date: January 22, 2004
    Inventors: Michael Simons, Ruediger Volk, Arie Horowitz