Patents by Inventor Michael Simurdiak

Michael Simurdiak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HIGHLY ACTIVE XYLOSE REDUCTASE FROM NEUROSPORA CRASSA
    Publication number: 20090325254
    Abstract: A new xylose reductase encoding gene from Neurspora crassa was heterologously expressed in E. coli as a His-tag fusion protein and subsequently purified in high yield. This xylose reductase was shown to have a high turnover rate and catalytic efficiency, high stability at room temperature, broad pH profile, and a preference of NADPH over NADH. This enzyme is utilized in production of xylitol and other sugar alcohols such as sorbitol and also in the metabolic enhancement of organisms used for fermentation of plant biomass into ethanol.
    Type: Application
    Filed: September 1, 2009
    Publication date: December 31, 2009
    Applicants: BIOTECHNOLOGY RESEARCH AND DEVELOPMENT CORPORATION, THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
    Inventors: Huimin Zhao, Ryan Woodyer, Michael Simurdiak, Wilfred A. van der Donk
  • Highly active xylose reductase from
    Patent number: 7592163
    Abstract: A new xylose reductase encoding gene from Neurspora crassa was heterologously expressed in E. coli as a His-tag fusion protein and subsequently purified in high yield. This xylose reductase was shown to have a high turnover rate and catalytic efficiency, high stability at room temperature, broad pH profile, and a preference of NADPH over NADH. This enzyme is utilized in production of xylitol and other sugar alcohols such as sorbitol and also in the metabolic enhancement of organisms used for fermentation of plant biomass into ethanol.
    Type: Grant
    Filed: May 19, 2008
    Date of Patent: September 22, 2009
    Assignees: The Board of Trustees of the University of Illinois, Biotechnology Research and Development Corporation
    Inventors: Huimin Zhao, Ryan Woodyer, Michael Simurdiak, Wilfred A. van der Donk
  • HIGHLY ACTIVE XYLOSE REDUCTASE FROM NEUROSPORA CRASSA
    Publication number: 20080241900
    Abstract: A new xylose reductase encoding gene from Neurspora crassa was heterologously expressed in E. coli as a His-tag fusion protein and subsequently purified in high yield. This xylose reductase was shown to have a high turnover rate and catalytic efficiency, high stability at room temperature, broad pH profile, and a preference of NADPH over NADH. This enzyme is utilized in production of xylitol and other sugar alcohols such as sorbitol and also in the metabolic enhancement of organisms used for fermentation of plant biomass into ethanol.
    Type: Application
    Filed: May 19, 2008
    Publication date: October 2, 2008
    Applicants: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, BIOTECHNOLOGY RESEARCH AND DEVELOPMENT CORPORATION
    Inventors: Huimin Zhao, Ryan Woodyer, Michael Simurdiak, Wilfred A. van der Donk
  • Highly active xylose reductase from
    Patent number: 7381553
    Abstract: A new xylose reductase encoding gene from Neurspora crassa was heterologously expressed in E. coli as a His-tag fusion protein and subsequently purified in high yield. This xylose reductase was shown to have a high turnover rate and catalytic efficiency, high stability at room temperature, broad pH profile, and a preference of NADPH over NADH. This enzyme is utilized in production of xylitol and other sugar alcohols such as sorbitol and also in the metabolic enhancement of organisms used for fermentation of plant biomass into ethanol.
    Type: Grant
    Filed: June 14, 2005
    Date of Patent: June 3, 2008
    Assignee: The Board of Trustees of the Universtiy of Illinois
    Inventors: Huimin Zhao, Ryan Woodyer, Michael Simurdiak, Wilfred A. van der Donk
  • Highly active xylose reductase from neurospora crassa
    Publication number: 20060035353
    Abstract: A new xylose reductase encoding gene from Neurspora crassa was heterologously expressed in E. coli as a His-tag fusion protein and subsequently purified in high yield. This xylose reductase was shown to have a high turnover rate and catalytic efficiency, high stability at room temperature, broad pH profile, and a preference of NADPH over NADH. This enzyme is utilized in production of xylitol and other sugar alcohols such as sorbitol and also in the metabolic enhancement of organisms used for fermentation of plant biomass into ethanol.
    Type: Application
    Filed: June 14, 2005
    Publication date: February 16, 2006
    Inventors: Huimin Zhao, Ryan Woodyer, Michael Simurdiak, Wilfred van der Donk