Patents by Inventor Michael Skjoet

Michael Skjoet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VARIANTS AND COMPOSITIONS COMPRISING VARIANTS WITH HIGH STABILITY IN PRESENCE OF A CHELATING AGENT
    Publication number: 20180010111
    Abstract: The present invention relates to variants of an alpha-amylase having improved stability to chelating agents relative to its parent enzyme, compositions comprising the variants, nucleic acids encoding the variants, methods of producing the variants, and methods for using the variants.
    Type: Application
    Filed: September 19, 2017
    Publication date: January 11, 2018
    Applicant: NOVOZYMES A/S
    Inventors: Allan Svendsen, Annette Helle Johansen, Mads Bjoernvad, Frank W. Rasmussen, Michael Skjoet, Signe Eskildsen Larsen, Jens Oebro, Svend Kaasgaard, Lars Beier
  • Cleaning compositions comprising amylase variant reference to a sequence listing
    Patent number: 9670436
    Abstract: The present invention relates to cleaning compositions comprising variants of an alpha-amylase and methods of treating surfaces such as textiles with aqueous liquor comprising such compositions, especially at low temperatures.
    Type: Grant
    Filed: February 3, 2016
    Date of Patent: June 6, 2017
    Assignee: The Procter & Gamble Company
    Inventors: Michelle Jackson, Philip Frank Souter, Lindsay Suzanne Bewick, Svend Kaasgaard, Jens Oebro, Signe Eskildsen Larsen, Allan Svendsen, Annette Helle Johansen, Michael Skjoet, Carsten Andersen, Lars Beier, Esben Peter Friis, Miguel Duarte Guilherme Pereira Toscano, Mads Bjoernvad, Frank Winther Rasmussen, Liv Spaangner Christiansen
  • Lipase variants for pharmaceutical use
    Patent number: 9539311
    Abstract: The pharmaceutical use of lipases related to the Thermomyces lanuginosus (Humicola lanuginosa) lipase comprising amino acids 1-269 of SEQ ID NO: 2, optionally in combination with a protease and/or an amylase. Examples of medical indications are: Treatment of digestive disorders, pancreatic exocrine insufficiency (PEI), pancreatitis, cystic fibrosis, diabetes type I, and/or diabetes type II. The lipases of the invention have, e.g., an improved digestion performance in vitro, an improved activity at a pH in the neutral range, an improved stability at low pH, an are stable against protease-degradation, and/or are stable in the presence of pepsin and bile salts. The invention also relates to methods of determining digestion performance in vitro of lipases, as well as to certain novel variants of the lipase of T. lanuginosus.
    Type: Grant
    Filed: April 6, 2015
    Date of Patent: January 10, 2017
    Assignees: Novozymes A/S, Novozymes Inc.
    Inventors: Allan Svendsen, Michael Skjoet, Debbie Yaver, Lars Lehmann Hylling Christensen, Signe Eskildsen Larsen, Nina Lundin, Michael Lamsa, Peter Colin Gregory
  • Variants of a Family 44 Xyloglucanase
    Publication number: 20160333330
    Abstract: The present invention relates to variants of a parent xyloglucanase. The present invention also relates to polynucleotides encoding the variant xyloglucanases and to nucleic acid constructs, vectors, and host cells comprising the polynucleotide.
    Type: Application
    Filed: June 6, 2016
    Publication date: November 17, 2016
    Applicant: Novozymes A/S
    Inventors: Werner Besenmatter, Esben Peter Friis, Keith Gibson, Frank Winther Rasmussen, Michael Skjoet
  • Cleaning composition comprising amylase variants with high stability in the presence of a chelating agent
    Patent number: 9493730
    Abstract: The present invention relates to cleaning compositions comprising variants of an alpha-amylase having improved stability to chelating agents relative to its parent enzyme and cleaning processes comprising such compositions.
    Type: Grant
    Filed: February 10, 2011
    Date of Patent: November 15, 2016
    Assignee: The Procter & Gamble Company
    Inventors: Michelle Meek, Philip Frank Souter, Lindsay Suzanne Bewick, Allan Svendsen, Annette Helle Johansen, Mads Eskelund Bjoernvad, Frank Winther Rasmussen, Michael Skjoet, Signe Eskildsen Larsen, Jens Oebro, Svend Kaasgaard, Lars Beier
  • ALPHA-AMYLASE VARIANTS
    Publication number: 20160326506
    Abstract: The present invention relates to variants of a parent alpha-amylase. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: July 25, 2016
    Publication date: November 10, 2016
    Applicant: NOVOZYMES A/S
    Inventors: Svend Kaasgaard, Jens Oebro, Signe Eskildsen Larsen, Allan Svendsen, Annette Helle Johansen, Michael Skjoet, Carsten Andersen, Lars Beier, Esben Peter Friis, Miguel Duarte Guilherme Pereira Toscano, Mads Bjoernvad, Frank Winther Rasmussen, Liv Spaanger Christiansen
  • Thermostable Phytase Variants
    Publication number: 20160289655
    Abstract: The present invention relates to a phytase which has at least 70% identity to a phytase derived from E. coli and comprises at least one modification as compared to this phytase. These phytase variants have modified, preferably improved, properties, such as thermostability, temperature profile, pH profile, specific activity, performance in animal feed, reduced protease sensitiliby, and/or an modified glycosylation pattern. The invention also relates to DNA encoding these phytases, methods of their production, as well as the use thereof, e.g., in animal feed and animal feed additives.
    Type: Application
    Filed: June 17, 2016
    Publication date: October 6, 2016
    Applicant: Novozymes A/S
    Inventors: Leonardo De Maria, Lars Kobberoee Skov, Michael Skjoet
  • Alpha-amylase variants
    Patent number: 9434932
    Abstract: The present invention relates to variants of a parent alpha-amylase. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: June 29, 2012
    Date of Patent: September 6, 2016
    Assignee: NOVOZYMES A/S
    Inventors: Svend Kaasgaard, Jens Oebro, Signe Eskildsen Larsen, Allan Svendsen, Annette Helle Johansen, Michael Skjoet, Carsten Andersen, Lars Beier, Esben Peter Friis, Miguel Duarte Guilherme Pereira Toscano, Mads Bjoernvad, Frank Winther Rasmussen, Liv Spaanger Christiansen
  • Variants of a family 44 xyloglucanase
    Patent number: 9382524
    Abstract: The present invention relates to variants of a parent xyloglucanase. The present invention also relates to polynucleotides encoding the variant xyloglucanases and to nucleic acid constructs, vectors, and host cells comprising the polynucleotide.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: July 5, 2016
    Assignee: Novozymes A/S
    Inventors: Werner Besenmatter, Esben Peter Friis, Keith Gibson, Frank Winther Rasmussen, Michael Skjoet
  • CLEANING COMPOSITIONS COMPRISING AMYLASE VARIANT REFERENCE TO A SEQUENCE LISTING
    Publication number: 20160177238
    Abstract: The present invention relates to cleaning compositions comprising variants of an alpha-amylase and methods of treating surfaces such as textiles with aqueous liquor comprising such compositions, especially at low temperatures.
    Type: Application
    Filed: February 3, 2016
    Publication date: June 23, 2016
    Inventors: Michelle JACKSON, Philip Frank SOUTER, Lindsay Suzanne BEWICK, Svend KAASGAARD, Jens OEBRO, Signe Eskildsen LARSEN, Allan SVENDSEN, Annette Helle JOHANSEN, Michael SKJOET, Carsten ANDERSEN, Lars BEIER, Esben Peter FRIIS, Miguel Duarte Guilherme Pereira TOSCANO, Mads BJOERNVAD, Frank Winther RASMUSSEN, Liv Spaangner CHRISTIANSEN
  • Cleaning compositions comprising amylase variants reference to a sequence listing
    Patent number: 9284544
    Abstract: The present invention relates to cleaning compositions comprising variants of an alpha-amylase and methods of treating surfaces such as textiles with aqueous liquor comprising such compositions, especially at low temperatures.
    Type: Grant
    Filed: June 29, 2012
    Date of Patent: March 15, 2016
    Assignee: The Procter & Gamble Company
    Inventors: Michelle Jackson, Philip Frank Souter, Lindsay Suzanne Bewick, Svend Kaasgaard, Jens Oebro, Signe Eskildsen Larsen, Allan Svendsen, Annette Helle Johansen, Michael Skjoet, Carsten Andersen, Lars Beier, Esben Peter Friis, Miguel Duarte Guilherme Pereira Toscano, Mads Bjoernvad, Frank Winther Rasmussen, Liv Spaangner Christiansen
  • Thermostable phytase variants
    Patent number: 9173421
    Abstract: The present invention relates to a method for producing phytase variants has at least 70% identity to a phytase derived from Buttiauxella and comprises at least one additional disulfide bond as compared to this phytase. These phytase variants have modified, preferably improved, properties, such as thermostability, temperature profile, pH profile, specific activity, performance in animal feed, reduced protease sensitiliby, and/or an modified glycosylation pattern. The invention also relates to the variants produced, DNA encoding these phytases, methods of their production, as well as the use thereof, e.g. in animal feed and animal feed additives.
    Type: Grant
    Filed: March 25, 2011
    Date of Patent: November 3, 2015
    Assignee: Novozymes A/S
    Inventors: Leonardo De Maria, Lars Kobberoee Skov, Michael Skjoet
  • GLUCOAMYLASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME AND USES THEREOF
    Publication number: 20150232824
    Abstract: The present invention relates to variants of a parent glucoamylase. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the glucoamylase variants.
    Type: Application
    Filed: September 6, 2013
    Publication date: August 20, 2015
    Inventors: Jesper Vind, Esben Peter Friis, Thomas Agsersten Poulsen, Michael Skjøt, Peter Kamp Hansen, Frank Winther Rasmussen, Steen Krogsgaard, Joyce Craig, Guillermo Coward-Kelly, Keiichi Ayabe
  • Lipase Variants for Pharmaceutical Use
    Publication number: 20150209414
    Abstract: The pharmaceutical use of lipases related to the Thermomyces lanuginosus (Humicola lanuginosa) lipase comprising amino acids 1-269 of SEQ ID NO: 2, optionally in combination with a protease and/or an amylase. Examples of medical indications are: Treatment of digestive disorders, pancreatic exocrine insufficiency (PEI), pancreatitis, cystic fibrosis, diabetes type I, and/or diabetes type II. The lipases of the invention have, e.g., an improved digestion performance in vitro, an improved activity at a pH in the neutral range, an improved stability at low pH, an are stable against protease-degradation, and/or are stable in the presence of pepsin and bile salts. The invention also relates to methods of determining digestion performance in vitro of lipases, as well as to certain novel variants of the lipase of T. lanuginosus.
    Type: Application
    Filed: April 6, 2015
    Publication date: July 30, 2015
    Inventors: Allan Svendsen, Michael Skjoet, Deborah Yaver, Lars Lehmann Hylling Christensen, Signe Eskildsen Larsen, Nina Lundin, Michael Lamsa, Peter Colin Gregory
  • Lipase variants for pharmaceutical use
    Patent number: 9029115
    Abstract: The pharmaceutical use of lipases related to the Thermomyces lanuginosus (Humicola lanuginosa) lipase comprising amino acids 1-269 of SEQ ID NO: 2, optionally in combination with a protease and/or an amylase. Examples of medical indications are: Treatment of digestive disorders, pancreatic exocrine insufficiency (PEI), pancreatitis, cystic fibrosis, diabetes type I, and/or diabetes type II. The lipases of the invention have, e.g., an improved digestion performance in vitro, an improved activity at a pH in the neutral range, an improved stability at low pH, and are stable against protease-degradation, and/or are stable in the presence of pepsin and bile salts. The invention also relates to methods of determining digestion performance in vitro of lipases, as well as to certain novel variants of the lipase of T. lanuginosus.
    Type: Grant
    Filed: August 16, 2012
    Date of Patent: May 12, 2015
    Assignees: Novozymes A/S, Novozymes Inc
    Inventors: Allan Svendsen, Michael Skjoet, Deborah Yaver, Lars Lehmann Hylling Christensen, Signe Eskildsen Larsen, Nina Lundin, Michael Lamsa, Peter Colin Gregory
  • Lysozymes
    Publication number: 20150023945
    Abstract: The present invention is directed to lysozyme variants and nucleotide sequences encoding same. The lysozyme variants have antimicrobial and/or lysozyme activity and comprise an alteration of an amino acid sequence at one or more positions. The present invention is also directed to methods for producing and of using the Opisthocomus hoazin lysozyme and the lysozyme variants of the present invention as antimicrobial agents.
    Type: Application
    Filed: September 29, 2014
    Publication date: January 22, 2015
    Inventors: Mikkel Klausen, Marie Allesen Holm, Leonardo De Maria, Michael Skjoet
  • Variants of a Family 44 Xyloglucanase
    Publication number: 20140302586
    Abstract: The present invention relates to variants of a parent xyloglucanase. The present invention also relates to polynucleotides encoding the variant xyloglucanases and to nucleic acid constructs, vectors, and host cells comprising the polynucleotide.
    Type: Application
    Filed: February 28, 2014
    Publication date: October 9, 2014
    Applicant: Novozymes A/S
    Inventors: Werner Besenmatter, Esben Peter Friis, Keith Gibson, Frank Winther Rasmussen, Michael Skjoet
  • ALPHA-AMYLASE VARIANTS
    Publication number: 20140141489
    Abstract: The present invention relates to variants of a parent alpha-amylase. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: June 29, 2012
    Publication date: May 22, 2014
    Inventors: Svend Kaasgaard, Jens Oebro, Signe Eskildsen Larsen, Allan Svendsen, Annette Helle Johansen, Michael Skjoet, Carsten Andersen, Lars Beier, Esben Peter Friis, Miguel Duarte Guilherme Pereira Toscano, Mads Bjoernvad, Frank Winther Rasmussen, Liv Spaanger Christiansen
  • Variants of a family 44 xyloglucanase
    Patent number: 8709777
    Abstract: The present invention relates to variants of a parent xyloglucanase. The present invention also relates to polynucleotides encoding the variant xyloglucanases and to nucleic acid constructs, vectors, and host cells comprising the polynucleotide.
    Type: Grant
    Filed: June 4, 2009
    Date of Patent: April 29, 2014
    Assignee: Novozymes A/S
    Inventors: Werner Besenmatter, Esben Peter Friis, Keith Gibson, Frank Winther Rasmussen, Michael Skjoet
  • Lysozymes
    Publication number: 20130266554
    Abstract: The present invention is directed to lysozyme variants and nucleotide sequences encoding same. The lysozyme variants have antimicrobial and/or lysozyme activity and comprise an alteration of an amino acid sequence at one or more positions. The present invention is also directed to methods for producing and of using the Opisthocomus hoazin lysozyme and the lysozyme variants of the present invention as antimicrobial agents.
    Type: Application
    Filed: September 15, 2011
    Publication date: October 10, 2013
    Applicant: NOVOZYMES A/S
    Inventors: Mikkel Klausen, Marie Allesen Holm, Leonardo De Maria, Michael Skjoet