Patents by Inventor Michael Skoumal

Michael Skoumal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Functionalization of polymer scaffolds
    Patent number: 11879034
    Abstract: The disclosure provides a method of preparing a polymer scaffold including admixing a biotinylated reagent and a polymer to form a biotinylated polymer, subjecting the biotinylated polymer to conditions sufficient to form the polymer scaffold and optionally admixing the polymer scaffold with a streptavidin-modified biomolecule to form a biomolecule-modified polymer scaffold. The disclosure further provides a method of preparing a polymer scaffold including admixing a first click chemistry reagent and a poly(lactic-co-glycolic acid) (PLGA) polymer to form a modified PLGA polymer, subjecting the modified PLGA polymer to conditions sufficient to form the polymer scaffold, and optionally admixing the polymer scaffold with a biomolecule modified to include a second click chemistry reagent that selectively reacts with the first click chemistry reagent, to form a biomolecule-modified polymer scaffold.
    Type: Grant
    Filed: March 8, 2018
    Date of Patent: January 23, 2024
    Assignee: REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Lonnie D. Shea, Michael Skoumal, Ryan M. Pearson
  • Microporous hydrogel scaffolds for cell transplantation
    Patent number: 10973956
    Abstract: The present disclosure relates generally to biomaterial implants and methods for delivering a cell to an individual in need thereof and, more particularly, to biomaterial implants and techniques for delivering islets and/or ?-cell progenitors to an individual.
    Type: Grant
    Filed: January 5, 2018
    Date of Patent: April 13, 2021
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Tadas Kasputis, Michael Skoumal, Lonnie D. Shea
  • FUNCTIONALIZATION OF POLYMER SCAFFOLDS
    Publication number: 20200010611
    Abstract: The disclosure provides a method of preparing a polymer scaffold including admixing a biotinylated reagent and a polymer to form a biotinylated polymer, subjecting the biotinylated polymer to conditions sufficient to form the polymer scaffold and optionally admixing the polymer scaffold with a streptavidin-modified biomolecule to form a biomolecule-modified polymer scaffold. The disclosure further provides a method of preparing a polymer scaffold including admixing a first click chemistry reagent and a poly(lactic-co-glycolic acid) (PLGA) polymer to form a modified PLGA polymer, subjecting the modified PLGA polymer to conditions sufficient to form the polymer scaffold, and optionally admixing the polymer scaffold with a biomolecule modified to include a second click chemistry reagent that selectively reacts with the first click chemistry reagent, to form a biomolecule-modified polymer scaffold.
    Type: Application
    Filed: March 8, 2018
    Publication date: January 9, 2020
    Inventors: Lonnie D. Shea, Michael Skoumal, Ryan M. Pearson
  • Microporous Hydrogel Scaffolds for Cell Transplantation
    Publication number: 20180185550
    Abstract: The present disclosure relates generally to biomaterial implants and methods for delivering a cell to an individual in need thereof and, more particularly, to biomaterial implants and techniques for delivering islets and/or ?-cell progenitors to an individual.
    Type: Application
    Filed: January 5, 2018
    Publication date: July 5, 2018
    Inventors: Tadas Kasputis, Michael Skoumal, Lonnie D. Shea