Abstract: The invention is based on the finding that a subjects suffering from a viral infection and which is distinguished by a systemic inflammatory complication such as systemic endotheliitis are in particular indicated for a treatment with mesenchymal stromal cell (MSC) compositions. The invention provides treatments in the context of SARS Cov2 infections, in severely affected subjects receiving mechanical ventilation. Provided are MSC compositions for use in treatments, diagnostic stratification methods, and diagnostic kits for such purposes.

Abstract: The invention relates to anthracycline derivative compounds for treating tumor diseases, and related methods, compositions, and kits.

Abstract: The invention relates to anthracycline derivative compounds for treating tumor diseases, and related methods, compositions, and kits.

Abstract: The invention relates to compounds of the general formula (I) in which R1 is a hydrogen atom, a hydroxy or methoxy group, a halogen atom, or an NO2 group; R2 is a hydrogen atom, a hydroxy or methoxy group, or an acyl or aroyl group; R3 is hydrogen, trifluoroacetyl (C(?O)CF3), or p-nitrobenzoyl (C(?O)PhNO2), and in each case the wavy line represents both possible configurations of —OR3 relative to the skeleton; Y is [C(?O)], [C(?N)—OH], [CH—OH], or [CH—NR5R6] in the two possible stereoisomer arrangements, wherein R5 and R6 either each represent a hydrogen atom or a hydrogen atom and a trifluoroacetyl group (TFA); X=O, S, or NR, in which R=hydrogen or a C1 to C4 alkyl group; and R4 is an unbranched or branched alkyl or heteroalkyl chain with a chain length of 1 to 19 elements, maximally 6 heteroatoms (O, N, S) being separated from one another in any combination by at least two carbon atoms.