Patents by Inventor Michael ST. PAUL

Michael ST. PAUL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMPROVED T-CELLS FOR CANCER THERAPY USING AMINO ACID STARVATION PATHWAYS
    Publication number: 20240093150
    Abstract: There is described herein a method for improving the anti-cancer properties of T-cells, the method comprising: providing a population of T-cells; and culturing the T-cells in an environment that activates the GCN2 pathway.
    Type: Application
    Filed: January 18, 2022
    Publication date: March 21, 2024
    Inventors: Pamela OHASHI, Sam SAIBIL, Michael ST. PAUL
  • Anti-cancer T cells and their preparation using coenzyme A
    Patent number: 11547725
    Abstract: There is described herein, a method for inducing Tc22 lineage T cells from a population of CD8+ T cells, the method comprising: a) providing a population of CD8+ T cells; b) activating the population; and c) culturing or contacting the population of CD8+ T cells with Coenzyme A.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: January 10, 2023
    Assignee: UNIVERSITY HEALTH NETWORK
    Inventors: Pamela S. Ohashi, Michael St. Paul, Sam Saibil
  • Anti-tumor T cells and their preparation using IL-6
    Patent number: 11191782
    Abstract: There is described herein a method for inducing Tc22 lineage T cells from a population of CD8+ T cells, the method comprising: a) providing a population of CD8+ T cells; b) activating the population of CD8+ T cells; and c) culturing or contacting the population of CD8+ T cells with IL-6.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: December 7, 2021
    Assignee: UNIVERSITY HEALTH NETWORK
    Inventors: Pamela S. Ohashi, Michael St. Paul
  • ANTI-TUMOR T CELLS AND THEIR PREPARATION USING IL-6
    Publication number: 20200138862
    Abstract: There is described herein a method for inducing Tc22 lineage T cells from a population of CD8+ T cells, the method comprising: a) providing a population of CD8+ T cells; b) activating the population of CD8+ T cells; and c) culturing or contacting the population of CD8+ T cells with IL-6.
    Type: Application
    Filed: December 19, 2017
    Publication date: May 7, 2020
    Inventors: Pamela S. OHASHI, Michael ST. PAUL
  • ANTI-CANCER T CELLS AND THEIR PREPARATION USING COENZYME A
    Publication number: 20190365813
    Abstract: There is described herein, a method for inducing Tc22 lineage T cells from a population of CD8+ T cells, the method comprising: a) providing a population of CD8+ T cells; b) activating the population; and c) culturing or contacting the population of CD8+ T cells with Coenzyme A.
    Type: Application
    Filed: December 21, 2017
    Publication date: December 5, 2019
    Inventors: Pamela S. OHASHI, Michael ST. PAUL, Sam SAIBIL