Abstract: The present disclosure is related to a liquid viscoelastic swallowing aid formulated to promote safe swallowing of Solid Oral Dosage Forms (SODF), e.g., tablets and/or capsules, in a patient in need thereof, and uses of such a liquid viscoelastic swallowing aid.

Abstract: The present invention provides methods for treating or preventing aggression, agitation, irritability and/or anger in a subject comprising administrating to a subject in need thereof a therapeutically effective amount of a compound of Formula (I).

Abstract: In some implementations, a method may include obtaining target fault data indicating a preselected fault for a vehicle having a hydrogen source. In addition, the method may include obtaining vehicle fault data indicating a fault of the vehicle. The method may include identifying a match between the fault and the preselected fault. Moreover, the method may include purging, in response to the identifying the match, hydrogen from the hydrogen source so as to reduce consequences of a battery thermal event by reducing the likelihood of a hydrogen-fueled fire.

Abstract: A laminate includes a first glass article having a first thickness, a first annealing point (TA1), and a first softening point (TS1), a second glass article having a second thickness, a second annealing point (TA2), and a second softening point (TS2), and an interlayer disposed between the first glass article and the second glass article. The first thickness is greater than the second thickness, the second annealing point (TA2) is less than or equal to the first annealing point (TA1), and the second softening point (TS2) is greater than the first softening point (TS1).

Abstract: The present invention further relates to a waterborne dispersion comprising (A) polymer P; (B) amphiphilic block copolymer obtained with a controlled radical polymerization process and comprising at least blocks [A] and [B], whereby block [A] comprises ethylenically unsaturated monomer(s) bearing water-soluble and/or water-dispersible functional groups (monomer(s) (i)), and block [B] comprises ethylenically unsaturated monomer(s) different from monomer(s) (i) (monomer(s) (ii)); and (C) crosslinker, characterized in that the polymer P is crosslinkable and comprises ethylenically unsaturated monomer(s) bearing crosslinkable functional groups different from monomer(s) (i) and monomer(s) (ii) (monomer(s) (iii)) in an amount of from 1 to 10 wt. %, based on the total weight of monomers used to prepare the polymer P, the amount of lock copolymer is higher than 1 wt. % and lower than 30 wt.

Abstract: Devices, systems and methods for altering functioning of a tissue/organ by application of force thereto. In one preferred embodiment, a device for reducing or preventing regurgitation of blood through a valve of a heart is provided. A device may include a main body having a segment adapted to apply force to a surface of tissue/organ and a member that applies counterforce to the force applied by the segment. Kits are provided in which devices having varying lengths and widths can be selected for the best fit for a particular location of treatment. A width sizing instrument may be provided. A length sizing instrument may be provided. A separate sleeve and/or pad may be provided which may be first anchored to the tissue/organ before fixing the device thereto.

Abstract: A sponge counting system for maintaining an inventory of articles used during a medical or surgical procedure, where, in the event an article for which the status needs to be reconciled is left in a patient, the system generates a record that the article is in a partially reconciled state and when a subsequent procedure is performed, the scanner employed during the procedure has the records of the partially reconciled articles associated with the patient.

Abstract: The present invention relates to systems, methods, and apparatuses for the management, distribution, dispensing, and administration of consumer products, including over-the-counter and prescription medications through use of a product container labeling system and an optional integrated computer-based or online management system. In certain aspects, the invention relates to a product container comprising a hollow body, a child-resistant cap, and a specialized information label affixed to the hollow body.

Abstract: Apparatuses are provided for manufacturing a rod member for a cigarette filter element. Each rod member defines a longitudinal axis and includes a generally longitudinally-extending filter material and a plurality of objects disposed therein along the longitudinal axis. Such an apparatus comprises a rod-forming unit configured to form a continuous supply of a filter material into a continuous cylindrical rod member. An object insertion unit is configured to introduce a plurality of objects into engagement with the rod member. A rod-dividing unit is configured to divide the rod member into a plurality of rod portions such that each rod portion includes a plurality of the objects. Associated methods are also provided.

Abstract: A system and method for training a student employ a simulation station that displays output to the student and receives input. The computer system has a rules engine operating on it and computer accessible data storage storing (i) learning object data including learning objects configured to provide interaction with the student at the simulation system and (ii) rule data defining a plurality of rules accessed by the rules engine. The rules data includes, for each rule, respective (a) if-portion data defining a condition of data and (b) then-portion data defining an action to be performed at the simulation station. The rules engine causes the computer system to perform the action when the condition of data is present in the data storage. For at least some of the rules, the action comprises output of one of the learning objects so as to interact with the student. The system may be networked with middleware and adapters that map data received over the network to rules engine memory.

Abstract: Methods, systems, and computer program products for direct assignment of physical devices to confidential virtual machines (VMs). At a first guest privilege context of a guest partition, a direct assignment of a physical device associated with a host computer system to the guest partition is identified. The guest partition includes the first guest privilege context and a second guest privilege context, which is restricted from accessing memory associated with the first guest privilege context. The guest partition corresponds to a confidential VM, such that a memory region associated with the guest partition is inaccessible to a host operating system. It is determined, based on a policy, that the physical device is allowed to be directly assigned to the guest partition. Communication between the physical device and the second guest privilege context is permitted, such as by exposing the physical device on a virtual bus and/or forwarding an interrupt.

Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for recognizing speech using a spiking neural network acoustic model implemented on a neuromorphic processor are described. In one aspect, a method includes receiving, a trained acoustic model implemented as a spiking neural network (SNN) on a neuromorphic processor of a client device, a set of feature coefficients that represent acoustic energy of input audio received from a microphone communicably coupled to the client device. The acoustic model is trained to predict speech sounds based on input feature coefficients. The acoustic model generates output data indicating predicted speech sounds corresponding to the set of feature coefficients that represent the input audio received from the microphone. The neuromorphic processor updates one or more parameters of the acoustic model using one or more learning rules and the predicted speech sounds of the output data.

Abstract: The techniques described herein relate to methods and apparatus for firearm safety mechanisms, visual safety indicators, and related techniques. A firearm includes a handle comprising one or more buttons disposed at least partially within a surface of the handle, such that the one or more buttons can be in contact with an operator's hand when the operator grasps the handle; a safety mechanism in mechanical communication with the trigger. The safety mechanism comprises: a first position that blocks actuation of the trigger; and a second position that does not block actuation of the trigger; and at least one processor configured to: upon determining an input code matches a stored code, transmits a signal to the safety mechanism to change the safety mechanism from the first position to the second position so that the firearm can be fired by the operator.

Abstract: A charge coupler with integrated electrical and mechanical disconnect switching can include a first member. A charging coupler can include a first member and a second member. The second member can be coupled at a first end with the first member. A charging coupler can include a first switch disposed at the first member and operable to cause, in response to a movement of the second member to a first angle with the first member that engages the first switch, a charging device to electrically decouple the charging device from a vehicle. A charging coupler can include a second switch disposed at the first member and operable to cause, in response to a movement of the second member to a second angle with the first member that engages the second switch, the charging device to mechanically decouple the charging device from the vehicle.

Abstract: The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells wherein the CAR T cells comprise a CAR and the CAR comprises an E2 anti-fluorescein antibody fragment, and administering to the patient a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.

Abstract: This invention relates to a method of identifying mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, a kit for performing the method, and furthermore to isolated nucleotide sequences being complementary to one or more mutations of the CFTR gene. According to a first aspect of the invention there is provided a method of identifying mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, including the steps of providing one or more nucleic acid sequences, fully complementary to one or more segments of the CFTR gene, wherein the one or more nucleic acid sequences correspond to the mutation to be identified; providing a biological sample of an individual to be tested for CF; isolating nucleic acids from the biological sample; and testing the biological sample for the presence of one or more of the nucleic acid sequences using a suitable detection method.

Abstract: A method includes forming an assembly of layers including an InP cap layer on an InGaAs absorption region layer, wherein the InGaAs layer is on an n-InP layer, and wherein an underlying substrate layer underlies the n-InP layer. The method includes removing a portion of the InP cap and n-InP layer by dry etching.

Abstract: A vaginal dilation device is provided that may include any of a number of features. One feature of the vaginal dilation device is that it is configured to dilate vaginal tissue during labor to prevent tissue damage. Another feature of the vaginal dilation device is that it can be manually controlled to dilate vaginal tissue, or can be automatically controlled to dilate vaginal tissue. In some embodiments, the vaginal dilation device is configured to measure a force applied by the device to tissue. In other embodiments, the vaginal dilation device is configured to apply a constant force to tissue. In other embodiments, the vaginal dilation device is configured to expand at a constant rate. Methods associated with use of the vaginal dilation device are also provided.

Abstract: Techniques and systems for computer aided design of physical structures using an object splitting design process that optimize manufacturing efficiency are described. A described technique includes splitting, by a computer program, a three dimensional model of an initial object into an up skin region and a down skin region based on an analysis of draft angles along at least one surface of the three dimensional model of the initial object. The technique further includes producing, by the computer program, first and second three dimensional models of respective first and second objects in accordance with the up skin region and the down skin region to create separate first and second physical structures using one or more computer-controlled manufacturing systems such that the first and second physical structures are combinable to form a combined physical structure.