Abstract: The invention relates to a method of making solid cleansing compositions which comprise a non-soap anionic surfactant, a carrier, an emulsifier and water. The method entails preparing an emulsion of the components at an elevated temperature using excess water and subjecting the emulsion to cooling and solidification, wherein the water content is reduced. The invention further relates to the emulsions and to the novel solid cleansing compositions formed therefrom.

Abstract: The invention relates to solid personal cleansing compositions which comprise a non-soap anionic surfactant, a carrier, an emulsifier, a humectant and water. The method entails preparing an emulsion of the components at an elevated temperature and cooling the emulsion to produce a block which can be re-melted and additised with colour, fragrance by downstream processors. The invention further relates to the emulsions and to methods for preparing the cleansing compositions.

Abstract: A method includes receiving a first input indicating at least a selected controller type and generating, based on the first input, a model that represents a controller corresponding to the selected controller type. The method also includes receiving a second input indicating at least one functional aspect of the selected controller type, updating, based on the second input, the model to represent the at least one functional aspect of the selected controller type, and compiling, using the model, a binary file that represents, at least, the at least one functional aspect of the selected controller type. The method also includes uploading the binary file to a controller corresponding to the selected controller type.

Abstract: Tumor-Treating Fields elicit a conditional vulnerability to PARP inhibitors (e.g., Olaparib) in certain cancer cells such as non-small cell lung cancer (NSCLC) cell lines. This conditional vulnerability is exploited in a method of killing cancer cells that comprises delivering a PARP inhibitor to the cancer cells and applying an alternating 80-300 kHz electric field to the cancer cells. At least a portion of the applying step is performed simultaneously with at least a portion of the delivering step. In some embodiments, an additional step of treating the cancer cells with a radiation therapy is added to the method. In some embodiments, the frequency of the alternating electric field is between 100 and 200 kHz.

Abstract: The invention relates to a method of making solid cleansing compositions which comprise a non-soap anionic surfactant, a carrier, an emulsifier and water. The method entails preparing an emulsion of the components at an elevated temperature using excess water and subjecting the emulsion to cooling and solidification, wherein the water content is reduced. The invention further relates to the emulsions and to the novel solid cleansing compositions formed therefrom.

Abstract: Tumor-Treating Fields elicit a conditional vulnerability to PARP inhibitors (e.g., Olaparib) in certain cancer cells such as non-small cell lung cancer (NSCLC) cell lines. This conditional vulnerability is exploited in a method of killing cancer cells that comprises delivering a PARP inhibitor to the cancer cells and applying an alternating 80-300 kHz electric field to the cancer cells. At least a portion of the applying step is performed simultaneously with at least a portion of the delivering step. In some embodiments, an additional step of treating the cancer cells with a radiation therapy is added to the method. In some embodiments, the frequency of the alternating electric field is between 100 and 200 kHz.

Abstract: A method includes receiving a first input indicating at least a selected controller type and generating, based on the first input, a model that represents a controller corresponding to the selected controller type. The method also includes receiving a second input indicating at least one functional aspect of the selected controller type, updating, based on the second input, the model to represent the at least one functional aspect of the selected controller type, and compiling, using the model, a binary file that represents, at least, the at least one functional aspect of the selected controller type. The method also includes uploading the binary file to a controller corresponding to the selected controller type.

Abstract: Tumor-Treating Fields elicit a conditional vulnerability to PARP inhibitors (e.g., Olaparib) in certain cancer cells such as non-small cell lung cancer (NSCLC) cell lines. This conditional vulnerability is exploited in a method of killing cancer cells that comprises delivering a PARP inhibitor to the cancer cells and applying an alternating 80-300 kHz electric field to the cancer cells. At least a portion of the applying step is performed simultaneously with at least a portion of the delivering step. In some embodiments, an additional step of treating the cancer cells with a radiation therapy is added to the method. In some embodiments, the frequency of the alternating electric field is between 100 and 200 kHz.

Abstract: Vehicle restraints for use at loading docks are disclosed herein. In some embodiments, a vehicle restraint can include a frame mountable relative to a loading dock face, a restraining structure configured to engage, for example, a Rear Impact Guard (RIG) of a shipping vehicle, and a linkage operably coupling the restraining structure to the frame. The linkage can include a collapsible strut operably coupled between the frame and the restraining structure. In operation, the linkage can be raised to engage the restraining structure with the RIG and prevent the vehicle from moving away from the dock face. Additionally, the restraining structure can be disengaged from the RIG by collapsing the strut, even if the RIG is imparting a significant load on the restraining structure that might otherwise bind the restraining structure in the engaged position.

Abstract: Vehicle restraints for use at loading docks are disclosed herein. In some embodiments, a vehicle restraint can include a frame mountable relative to a loading dock face, a restraining structure configured to engage, for example, a Rear Impact Guard (RIG) of a shipping vehicle, and a linkage operably coupling the restraining structure to the frame. The linkage can include a collapsible strut operably coupled between the frame and the restraining structure. In operation, the linkage can be raised to engage the restraining structure with the RIG and prevent the vehicle from moving away from the dock face. Additionally, the restraining structure can be disengaged from the RIG by collapsing the strut, even if the RIG is imparting a significant load on the restraining structure that might otherwise bind the restraining structure in the engaged position.

Abstract: A transimpedance amplifier includes a current regulator having a first current mirror of a first conduction type and a first current mirror of a second conduction type. The first current mirror stage of a first conduction type receives a reference current. The first current mirror stage of a second conduction type is connected to the first current mirror stage of the first conduction type, and receives an output current from the first current mirror stage of the first conduction type, and to generate a current to be used as a current source by a transimpedance amplifier. Each of the current mirror stages includes a first transistor and a second transistor of the same conduction type having their gate terminals connected wherein the first transistor receives an input current and the second transistor provides an output current that is a factor of the received input current.

Abstract: A transimpedance amplifier includes a current regulator having a first current mirror of a first conduction type and a first current mirror of a second conduction type. The first current mirror stage of a first conduction type receives a reference current. The first current mirror stage of a second conduction type is connected to the first current mirror stage of the first conduction type, and receives an output current from the first current mirror stage of the first conduction type, and to generate a current to be used as a current source by a transimpedance amplifier. Each of the current mirror stages includes a first transistor and a second transistor of the same conduction type having their gate terminals connected wherein the first transistor receives an input current and the second transistor provides an output current that is a factor of the received input current.

Abstract: The present invention relates to an artificially carbonated beverage containing a foam control agent and/or carbon dioxide control agent, the control agent comprising a polyglycerol fatty acid ester. A sealed container containing such a beverage, a concentrate for such a beverage, a method of making such a beverage and a method of reducing foaming and/or improving retention of carbon dioxide in such a beverage, are also described.

Abstract: Technology generally directed to operation of loading dock equipment such as vehicle restraints, dock levelers, overhead doors/openers, barrier gates, lights, and linked or unlinked control systems is disclosed herein. The disclosed technology may be employed to power electrical loading dock systems from batteries and/or alternative power sources, including “green” power sources. For example, the technology may be employed at new, temporary, and/or mobile facilities having any number of loading docks where reliable commercial power may not be readily available. Further, the technology may also be employed at warehouses in remote and/or developing areas where electrical infrastructure is not available and/or reasonably priced. The technology may be embodied as methods, apparatuses, manufactures (e.g., computer- and/or processor-readable storage and/or other mediums), and/or the like.

Abstract: A phase locked loop comprising: an oscillator for generating an output signal of a frequency that is dependent on an input to the oscillator; sampling means for generating a sequence of digital values representing the output of the oscillator at moments synchronized with a reference frequency; a difference unit for generating a feedback signal representing the difference between successive values in the sequence; and an integrator for integrating the difference between the feedback signal and a signal of a desired output frequency; the signal input to the oscillator being dependent on the output of the integrator.

Abstract: A pack comprising a block of personal cleansing composition cast in a receptacle, wherein: the personal cleansing composition is solid at an ambient temperature and liquid at an elevated temperature; the personal cleansing composition is in direct contact with the receptacle; the receptacle is resistant to the liquid form of the personal cleansing composition; and the receptacle is configurable into a collapsed form to free the block.

Abstract: Dock levelers, such as mechanical dock levelers, are described herein. In one embodiment, a mechanical dock leveler includes a ramp having a lip pivotally attached to a forward edge. A ramp lifting system is configured to assist upward rotation of the ramp as it is manually raised. In this embodiment, a lip lifting system is operably coupled to the ramp lifting system so that the ramp is initially “downward biased” prior to being raised, and then becomes at least partially supported in a raised position by the lip lifting mechanism, once the lip lifting mechanism is engaged.

Abstract: The splicing variant D of the TAK1 gene is activated by short double-stranded RNAs in a sequence specific manner. Activation of TAK1-D leads to the downstream activation of the p38 MAPK and of SAPK/JNK but not the NF?B pathway. The current invention therefore provides a method of inducing apoptosis and/or cell cycle arrest in a cancer cell comprising contacting said cell with an agonist of Tak1-D function. The invention further provides a method of modulating inflammation and the treatment of cancer by the administration of an agonist of Tak1-D function or expression. In yet another aspect, the invention provides a method of inducing p38 MAPK and SAPK/JNK signaling in a cell comprising contacting said cell with an agonist of Tak1-D function or expression.

Abstract: Dock leveler seals and associated methods and systems are described herein. A dock leveler having a rear hinge seal configured in accordance with one embodiment of the disclosure includes a rear support frame and a movable deck. The rear support frame includes a plurality of first support members extending therefrom, and the aft edge portion of the deck includes a plurality of second support members pivotally coupled to the first support members along an axis. The seal of this embodiment includes a first edge portion extending outwardly from a medial portion in a first direction, and a second edge portion extending outwardly from the medial portion in a second direction. The medial portion urges the first edge portion against the support frame and the second edge portion against the aft edge portion of the deck as the deck pivots about the axis in operation.

Abstract: Technology generally directed to operation of loading dock equipment such as vehicle restraints, dock levelers, overhead doors/openers, barrier gates, lights, and linked or unlinked control systems is disclosed herein. The disclosed technology may be employed to power electrical loading dock systems from batteries and/or alternative power sources, including “green” power sources. For example, the technology may be employed at new, temporary, and/or mobile facilities having any number of loading docks where reliable commercial power may not be readily available. Further, the technology may also be employed at warehouses in remote and/or developing areas where electrical infrastructure is not available and/or reasonably priced. The technology may be embodied as methods, apparatuses, manufactures (e.g., computer- and/or processor-readable storage and/or other mediums), and/or the like.