Patents by Inventor Michael Stroehlein

Michael Stroehlein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Initial relative lymphocyte count as predictive biomarker
    Patent number: 9772327
    Abstract: The invention relates to a method for predicting an improved therapeutic benefit for an individual with a tumor load before initiating an immune therapy which is capable of activating immune cells against said tumor as well as to pharmaceutical compositions for use in this method.
    Type: Grant
    Filed: May 16, 2012
    Date of Patent: September 26, 2017
    Inventors: Horst Lindhofer, Markus Heiss, Michael Stroehlein
  • Removal of tumor cells from intraoperative autologous blood salvage
    Patent number: 9605242
    Abstract: The invention relates to a method performed ex vivo for removal of tumor cells from intraoperatively collected blood salvage, to antibodies and scaffold proteins which mimic antibodies for use in said ex vivo method, to the use of said ex vivo method for removal of tumor cells from intraoperatively collected blood salvage followed by reintroducing the so obtained purified blood salvage or of concentrates of erythrocytes purified by said method to a patient from whom said intra-operatively collected blood was obtained, as well as to blood salvage or a concentrate of erythrocytes, both obtainable by said method for reinfusion to said patient.
    Type: Grant
    Filed: October 4, 2012
    Date of Patent: March 28, 2017
    Assignee: Horst Lindhofer
    Inventors: Horst Lindhofer, Michael Stroehlein, Markus Heiss
  • INITIAL RELATIVE LYMPHOCYTE COUNT AS PREDICTIVE BIOMARKER
    Publication number: 20150037278
    Abstract: The invention relates to a method for predicting an improved therapeutic benefit for an individual with a tumor load before initiating an immune therapy which is capable of activating immune cells against said tumor as well as to pharmaceutical compositions for use in this method.
    Type: Application
    Filed: May 16, 2012
    Publication date: February 5, 2015
    Applicants: Michael Stroehlein, Markus Heiss
    Inventors: Horst Lindhofer, Markus Heis, Michael Stroehlein
  • REMOVAL OF TUMOR CELLS FROM INTRAOPERATIVE AUTOLOGOUS BLOOD SALVAGE
    Publication number: 20140369985
    Abstract: The invention relates to a method performed ex vivo for removal of tumor cells from intraoperatively collected blood salvage, to antibodies and scaffold proteins which mimic antibodies for use in said ex vivo method, to the use of said ex vivo method for removal of tumor cells from intraoperatively collected blood salvage followed by reintroducing the so obtained purified blood salvage or of concentrates of erythrocytes purified by said method to a patient from whom said intra-operatively collected blood was obtained, as well as to blood salvage or a concentrate of erythrocytes, both obtainable by said method for reinfusion to said patient.
    Type: Application
    Filed: October 4, 2012
    Publication date: December 18, 2014
    Applicant: TRION PHARMA GMBH
    Inventors: Horst Lindhofer, Michael Stroehlein, Markus Heiss