Abstract: An air mouse system is described. The air mouse is configured to periodically transmit RF signals in order to trigger a plurality of ultrasonic transmitters arranged on a television. The ultrasonic transmitters transmit ultrasonic signals when being triggered by the RF signals from the RF trigger. An ultrasonic receiver receives the ultrasonic signals. A processor calculates a location of the air mouse with respect to the ultrasonic transmitters based on time differences of the ultrasonic signals transmitted by the ultrasonic transmitters arriving at the ultrasonic receiver. A series of locations of the air mouse forms a motion trail of the air mouse and the air mouse transmits the motion trail to the television wirelessly. The motion trail is projected as a cursor trail on the television screen by the television, to control the cursor on the television screen by virtue of the motion of the air mouse.

Abstract: Disclosed are methods of purifying mixtures comprising benzoidiazepine antibody-drug conjugates.

Abstract: Methods for the treatment of CD30-expressing cancers are provided. The methods comprise administering to a subject in need thereof a weekly dose of from about 0.8 mg/kg to about 1.8 mg/kg of an antibody-drug conjugate compound having formula (I); or a pharmaceutically acceptable salt thereof; wherein: mAb is an anti-CD30 antibody unit, S is a sulfur atom of the antibody, A- is a Stretcher unit, and p is from about 3 to about 5.

Abstract: An injection molding tool for molded-in-color injection molding is disclosed. The tool includes a first mold half that includes a mold cavity, a second molding half that includes a molding core, an ejector pin fluidly associated with the first mold half, and a gas removal vacuum system fluidly associated with the ejector pin. The first mold half and the second mold half meet at a parting line that is free of vents. In operation, the two halves are brought together, defining a mold cavity therebetween. The gas removal vacuum system is activated to remove any air that is trapped between the two halves. Once the trapped air has been removed, an article-forming, polymerizable resin is injected into the mold cavity. The gas removal vacuum system is again operated to remove gas generated by the polymerizable resin during the injection process.

Abstract: A one-piece trim bezel formed from multiple components. In the event of two co-molded components, the first co-molded part is composed of a polymerized material having an unpainted surface that may be a high gloss smooth surface or a textured low gloss surface and the second co-molded part, formed with the first part, is composed of a plateable plastic material. The plateable plastic material may be plateable with chrome. A multiple-shot injection molding process is used to form the one-piece trim bezel which joins the first co-molded part and the second co-molded part in one operation. The formed part is then subjected to a plating process during which time the chrome only deposits on the surface of the plateable plastic material of the second co-molded part while the surface of the first co-molded part remains unplated.

Abstract: An injection molding apparatus and method are provided. The method includes a molded cavity coupled to a resin injection apparatus which injects molten resin under pressure with a gas such that the resin foams within the mold cavity. An electrical heater is in contact with a first cavity surface, and a cooling medium cools the mold. The resin may include metallic flakes.

Abstract: An energy absorbing panel assembly for the interior of a motor vehicle is disclosed. The energy absorbing panel assembly, typically the knee bolster panel adjacent the steering wheel, includes an energy absorbing structure integrally molded to the panel. The energy absorbing structure includes three outer side walls and a top wall. The outer side walls extend from the same side of the top wall to the panel. Extending from the top wall to the panel is at least one top wall supporting rib. The rib is positioned between the outer side walls. At least one of the outer walls is at an obtuse angle relative to the plane of the top wall. All three of the outer walls may be at an obtuse angle relative to the plane of the top wall. Lateral supports may be provided between the outer side walls and the panel.

Abstract: A one-piece trim bezel formed from multiple components. In the event of two co-molded components, the first co-molded part is composed of a polymerized material having an unpainted surface that may be a high gloss smooth surface or a textured low gloss surface and the second co-molded part, formed with the first part, is composed of a plateable plastic material. The second co-molded part is co-molded with the said first co-molded part to form a single piece trim bezel. The color of the polymerized material of the first co-molded part may be selected from a variety of colors. The plateable plastic material may be plateable with chrome. A multiple-shot injection molding process is used to form the one-piece trim bezel which joins the first co-molded part and the second co-molded part in one operation.

Abstract: An injection molding apparatus and method are provided. The method includes a molded cavity coupled to a resin injection apparatus which injects molten resin under pressure with a gas such that the resin foams within the mold cavity. An electrical heater is in contact with a first cavity surface, and a cooling medium cools the mold. The resin may include metallic flakes.

Abstract: Methods for the treatment of CD30-expressing cancers are provided. The methods comprise administering to a subject in need thereof a weekly dose of from about 0.8 mg/kg to about 1.8 mg/kg of an antibody-drug conjugate compound having formula (I); or a pharmaceutically acceptable salt thereof; wherein: mAb is an anti-CD30 antibody unit, S is a sulfur atom of the antibody, A—is a Stretcher unit, and p is from about 3 to about 5.

Abstract: An energy absorbing panel assembly for the interior of a motor vehicle is disclosed. The energy absorbing panel assembly, typically the knee bolster panel adjacent the steering wheel, includes an energy absorbing structure integrally molded to the panel. The energy absorbing structure includes three outer side walls and a top wall. The outer side walls extend from the same side of the top wall to the panel. Extending from the top wall to the panel is at least one top wall supporting rib. The rib is positioned between the outer side walls. Ordinarily at least two such ribs will be provided. At least one of the outer walls is at an obtuse angle relative to the plane of the top wall. All three of the outer walls may be at an obtuse angle relative to the plane of the top wall.

Abstract: An instrument panel assembly for a passenger vehicle is provided with a protective film. The protective film has only one unfolded layer. The film layer is sized to cover an opening in an instrument panel. The opening is sized for an airbag to deploy through. The film layer is provided with a slit for separating into portions. The portions extend through the instrument panel as the airbag deploys. The protective film prevents the airbag from being damaged. The film layer also prevents the airbag from damaging the instrument panel. The instrument panel may be provided with a door for selectively covering the opening. The instrument panel assembly may include a hinge for pivotally connecting the door to the instrument panel.

Abstract: A protein containing one or more activatable groups, e.g., an antibody, is subjected to partial or complete reduction of one or more such bonds to form reactive groups; the resulting protein is reacted with a drug which is reactive with some of the reactive groups, such as certain radiometals, chelating agents, and toxins, so as to form a conjugate useful in, e.g., in vitro diagnosis, in vivo imaging, and therapy.

Abstract: An instrument panel assembly for a passenger vehicle is provided with a protective film. The protective film has only one unfolded layer. The film layer is sized to cover an opening in an instrument panel. The opening is sized for an airbag to deploy through. The film layer is provided with a slit for separating into portions. The portions extend through the instrument panel as the airbag deploys. The protective film prevents the airbag from being damaged. The film layer also prevents the airbag from damaging the instrument panel. The instrument panel may be provided with a door for selectively covering the opening. The instrument panel assembly may include a hinge for pivotally connecting the door to the instrument panel.

Abstract: A protein containing one or more activatable groups, e.g., an antibody, is subjected to partial or complete reduction of one or more such bonds to form reactive groups; the resulting protein is reacted with a drug which is reactive with some of the reactive groups, such as certain radiometals, chelating agents, and toxins, so as to form a conjugate useful in, e.g., in vitro diagnosis, in vivo imaging, and therapy.

Abstract: A system and method for managing codes during distributed software development. Code segments, or sections, are separated into logic units. Each logic unit contains one or more services. The logic units and services are registered at a registration management module, and added to the existing software code. When predefined automatic calling condition is satisfied, the corresponding service in every registered logic unit will be called automatically. Additionally, a unified interface is provided for calling services in the registered logic units. The calling of the logic unit may be affected by using the registration information of and/or a service definition defining the service of the logic unit maintained in the registration management module.

Abstract: A protein containing one or more activatable groups, e.g., an antibody, is subjected to partial or complete reduction of one or more such bonds to form reactive groups; the resulting protein is reacted with a drug which is reactive with some of the reactive groups, such as certain radiometals, chelating agents, and toxins, so as to form a conjugate useful in, e.g., in vitro diagnosis, in vivo imaging, and therapy.

Abstract: A system and method for managing codes during distributed software development. Code segments, or sections, are separated into logic units. Each logic unit contains one or more services. The logic units and services are registered at a registration management module, and added to the existing software code. When predefined automatic calling condition is satisfied, the corresponding service in every registered logic unit will be called automatically. Additionally, a unified interface is provided for calling services in the registered logic units. The calling of the logic unit may be affected by using the registration information of and/or a service definition defining the service of the logic unit maintained in the registration management module.

Abstract: A computer program product for calculating a tax amount where multiple types of taxes may apply to a transaction is tangibly embodied in an information carrier and includes first data structures comprising tax formulas. Each of the tax formulas is associated with one of several tax types. The computer program product includes second data structures comprising tax combinations of the several tax types, each tax combination having associated therewith at least one of the several tax types, one of the tax combinations to be selected for use with a specific transaction. The computer program product includes executable instructions that when executed determine, from information associated with the specific transaction, which one of the tax combinations to use in calculating a tax amount for the specific transaction, the tax amount to be calculated using the formula associated with any of the tax types included in the selected tax combination.

Abstract: A system and method for avoiding a single point of failure in the broadcast of streaming data. The system uses multiple redundant servers steaming the exactly same data to a failover device. The failover device buffers the steams into a primary and secondary data stream and automatically switches from the primary to the secondary data stream if it detects a corruption in the primary data stream. Since the buffered data packets of the two steams are identical and are synchronized, there is not outage for multicast receivers when the primary data source fails since there is a switch to exactly the same data in the next packet of the secondary data stream.