Patents by Inventor Michael Suster

Michael Suster has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240110884
    Abstract: As one example, an apparatus includes a dielectric microsensor having a microfluidic chamber that includes a capacitive sensing structure. The microfluidic chamber is adapted to receive a volume of a blood sample, and a bioactive agent is adapted to interact with the blood sample, as a sample under test (SUT), within the microfluidic chamber. A transmitter can provide an input radio frequency (RF) signal to the dielectric microsensor, and a receiver can receive an output RF signal from the dielectric microsensor. A computing device is configured to compute dielectric permittivity values for the SUT based on the output RF signal over a time interval in which the dielectric permittivity values are representative of the bioactive agent interacting with the blood sample over the time interval. The computing device is further configured to provide a readout representative of hemostatic dysfunction for the blood sample based on the dielectric permittivity values.
    Type: Application
    Filed: August 21, 2023
    Publication date: April 4, 2024
    Inventors: Pedram Mohseni, Lalitha Nayak, Michael Suster, Sina Pourang
  • Patent number: 11774388
    Abstract: As one example, an apparatus includes a dielectric microsensor having a microfluidic chamber that includes a capacitive sensing structure. The microfluidic chamber is adapted to receive a volume of a blood sample, and a bioactive agent is adapted to interact with the blood sample, as a sample under test (SUT), within the microfluidic chamber. A transmitter can provide an input radio frequency (RF) signal to the dielectric microsensor, and a receiver can receive an output RF signal from the dielectric microsensor. A computing device is configured to compute dielectric permittivity values for the SUT based on the output RF signal over a time interval in which the dielectric permittivity values are representative of the bioactive agent interacting with the blood sample over the time interval. The computing device is further configured to provide a readout representative of hemostatic dysfunction for the blood sample based on the dielectric permittivity values.
    Type: Grant
    Filed: June 29, 2022
    Date of Patent: October 3, 2023
    Assignees: CASE WESTERN RESERVE UNIVERSITY, UNIVERSITY HOSPITALS CLEVELAND MEDICAL CENTER
    Inventors: Pedram Mohseni, Lalitha Nayak, Michael Suster, Sina Pourang
  • Publication number: 20220326170
    Abstract: As one example, an apparatus includes a dielectric microsensor having a microfluidic chamber that includes a capacitive sensing structure. The microfluidic chamber is adapted to receive a volume of a blood sample, and a bioactive agent is adapted to interact with the blood sample, as a sample under test (SUT), within the microfluidic chamber. A transmitter can provide an input radio frequency (RF) signal to the dielectric microsensor, and a receiver can receive an output RF signal from the dielectric microsensor. A computing device is configured to compute dielectric permittivity values for the SUT based on the output RF signal over a time interval in which the dielectric permittivity values are representative of the bioactive agent interacting with the blood sample over the time interval. The computing device is further configured to provide a readout representative of hemostatic dysfunction for the blood sample based on the dielectric permittivity values.
    Type: Application
    Filed: June 29, 2022
    Publication date: October 13, 2022
    Inventors: Pedram Mohseni, Lalitha Nayak, Michael Suster, Sina Pourang
  • Patent number: 11408844
    Abstract: As one example, an apparatus includes a dielectric microsensor comprising a microfluidic chamber that includes a capacitive sensing structure, the microfluidic chamber including a fluid input port to receive a volume of a blood sample. A bioactive agent is disposed within the chamber to interact with the volume of the blood sample received in the microfluidic chamber. A transmitter provides an input radio frequency (RF) signal to an RF input of the dielectric microsensor. A receiver receives an output RF signal from an RF output of the dielectric microsensor. A computing device that computes dielectric permittivity values of the sample that vary over a time interval based on the output RF signal, the computing device to provide an assessment of hemostatic dysfunction and associated coagulopathy based on the dielectric permittivity values.
    Type: Grant
    Filed: April 1, 2020
    Date of Patent: August 9, 2022
    Assignees: CASE WESTERN RESERVE UNIVERSITY, THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERAN AFFAIRS, UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: Michael Suster, Pedram Mohseni, Anirban Sen Gupta, Matthew David Neal, Ujjal Didar Singh Sekhon, Sanjay Pitamber Ahuja, Sina Pourang, Debnath Maji
  • Patent number: 11175252
    Abstract: As one example, a fluid monitoring apparatus includes a dielectric microsensor that includes a capacitive sensing structure integrated into a microfluidic channel. The microfluidic channel includes a fluid input to receive a sample volume of a sample under test (SUT). A transmitter provides an input radio frequency (RF) signal to an RF input of the microsensor. A receiver receives an output RF signal from the microsensor. A computing device computes dielectric permittivity values of the SUT that vary over a time interval based on the output RF signal. The computing device may determine an indication of platelet count based on the computed dielectric permittivity values over at least a portion of the time interval.
    Type: Grant
    Filed: January 22, 2019
    Date of Patent: November 16, 2021
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Michael Suster, Pedram Mohseni, Debnath Maji, Umut Gurkan
  • Patent number: 11058316
    Abstract: As one example, a fluid monitoring apparatus includes a dielectric microsensor that includes a capacitive sensing structure integrated into a microfluidic channel. The microfluidic channel includes a fluid input to receive a sample volume of a sample under test (SUT). A transmitter provides an input radio frequency (RF) signal to an RF input of the microsensor. A receiver receives an output RF signal from the microsensor. A computing device computes dielectric permittivity values of the SUT that vary over a time interval based on the output RF signal. The computing device may determine at least one permittivity parameter based on the computed dielectric permittivity values over at least a portion of the time interval.
    Type: Grant
    Filed: May 8, 2020
    Date of Patent: July 13, 2021
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Michael Suster, Pedram Mohseni, Debnath Maji, Evi Stavrou, Umut Gurkan
  • Publication number: 20200405173
    Abstract: As one example, a fluid monitoring apparatus includes a dielectric microsensor that includes a capacitive sensing structure integrated into a microfluidic channel. The microfluidic channel includes a fluid input to receive a sample volume of a sample under test (SUT). A transmitter provides an input radio frequency (RF) signal to an RF input of the microsensor. A receiver receives an output RF signal from the microsensor. A computing device computes dielectric permittivity values of the SUT that vary over a time interval based on the output RF signal. The computing device may determine at least one permittivity parameter based on the computed dielectric permittivity values over at least a portion of the time interval.
    Type: Application
    Filed: May 8, 2020
    Publication date: December 31, 2020
    Inventors: Michael Suster, Pedram Mohseni, Debnath Maji, Evi Stavrou, Umut Gurkan
  • Publication number: 20200319128
    Abstract: As one example, an apparatus includes a dielectric microsensor comprising a microfluidic chamber that includes a capacitive sensing structure, the microfluidic chamber including a fluid input port to receive a volume of a blood sample. A bioactive agent is disposed within the chamber to interact with the volume of the blood sample received in the microfluidic chamber. A transmitter provides an input radio frequency (RF) signal to an RF input of the dielectric microsensor. A receiver receives an output RF signal from an RF output of the dielectric microsensor. A computing device that computes dielectric permittivity values of the sample that vary over a time interval based on the output RF signal, the computing device to provide an assessment of hemostatic dysfunction and associated coagulopathy based on the dielectric permittivity values.
    Type: Application
    Filed: April 1, 2020
    Publication date: October 8, 2020
    Inventors: Michael Suster, Pedram Mohseni, Anirban Sen Gupta, Matthew David Neal, Ujjal Didar Singh Sekhon, Sanjay Pitamber Ahuja, Sina Pourang, Debnath Maji
  • Patent number: 10674931
    Abstract: As one example, a fluid monitoring apparatus includes a dielectric microsensor that includes a capacitive sensing structure integrated into a microfluidic channel. The microfluidic channel includes a fluid input to receive a sample volume of a sample under test (SUT). A transmitter provides an input radio frequency (RF) signal to an RF input of the microsensor. A receiver receives an output RF signal from the microsensor. A computing device computes dielectric permittivity values of the SUT that vary over a time interval based on the output RF signal. The computing device may determine at least one permittivity parameter based on the computed dielectric permittivity values over at least a portion of the time interval.
    Type: Grant
    Filed: January 17, 2017
    Date of Patent: June 9, 2020
    Assignees: CASE WESTERN RESERVE UNIVERSITY, THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERAN AFFAIRS
    Inventors: Michael Suster, Pedram Mohseni, Debnath Maji, Evi Stavrou, Umut Gurkan
  • Publication number: 20190154603
    Abstract: As one example, a fluid monitoring apparatus includes a dielectric microsensor that includes a capacitive sensing structure integrated into a microfluidic channel. The microfluidic channel includes a fluid input to receive a sample volume of a sample under test (SUT). A transmitter provides an input radio frequency (RF) signal to an RF input of the microsensor. A receiver receives an output RF signal from the microsensor. A computing device computes dielectric permittivity values of the SUT that vary over a time interval based on the output RF signal. The computing device may determine an indication of platelet count based on the computed dielectric permittivity values over at least a portion of the time interval.
    Type: Application
    Filed: January 22, 2019
    Publication date: May 23, 2019
    Inventors: Michael Suster, Pedram Mohseni, Debnath Maji, Umut Gurkan
  • Publication number: 20190029555
    Abstract: As one example, a fluid monitoring apparatus includes a dielectric microsensor that includes a capacitive sensing structure integrated into a microfluidic channel. The microfluidic channel includes a fluid input to receive a sample volume of a sample under test (SUT). A transmitter provides an input radio frequency (RF) signal to an RF input of the microsensor. A receiver receives an output RF signal from the microsensor. A computing device computes dielectric permittivity values of the SUT that vary over a time interval based on the output RF signal. The computing device may determine at least one permittivity parameter based on the computed dielectric permittivity values over at least a portion of the time interval.
    Type: Application
    Filed: January 17, 2017
    Publication date: January 31, 2019
    Inventors: Michael Suster, Michael Mohseni, Debnath Maji, Evi Stavrou, Umut Gurkan
  • Patent number: 9995701
    Abstract: A sensor system can be configured to perform dielectric spectroscopy (DS). For example, the system can include a sensor configured to measure dielectric permittivity of a fluid in response to an RF input signal. Associated interface electronics can include a transmitter to drive the sensor with the RF input signal and a receiver to receive and process an RF output signal from the sensor in response to the RF input signal.
    Type: Grant
    Filed: June 2, 2015
    Date of Patent: June 12, 2018
    Assignee: Case Western Reserve University
    Inventors: Pedram Mohseni, Michael A. Suster, Mehran Bakshiani, Umut Gurkan
  • Publication number: 20150346131
    Abstract: A sensor system can be configured to perform dielectric spectroscopy (DS). For example, the system can include a sensor configured to measure dielectric permittivity of a fluid in response to an RF input signal. Associated interface electronics can include a transmitter to drive the sensor with the RF input signal and a receiver to receive and process an RF output signal from the sensor in response to the RF input signal.
    Type: Application
    Filed: June 2, 2015
    Publication date: December 3, 2015
    Inventors: Pedram Mohseni, Michael A. Suster, Mehran Bakshiani, Umut Gurkan