Patents by Inventor Michael Suster
Michael Suster has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240110884Abstract: As one example, an apparatus includes a dielectric microsensor having a microfluidic chamber that includes a capacitive sensing structure. The microfluidic chamber is adapted to receive a volume of a blood sample, and a bioactive agent is adapted to interact with the blood sample, as a sample under test (SUT), within the microfluidic chamber. A transmitter can provide an input radio frequency (RF) signal to the dielectric microsensor, and a receiver can receive an output RF signal from the dielectric microsensor. A computing device is configured to compute dielectric permittivity values for the SUT based on the output RF signal over a time interval in which the dielectric permittivity values are representative of the bioactive agent interacting with the blood sample over the time interval. The computing device is further configured to provide a readout representative of hemostatic dysfunction for the blood sample based on the dielectric permittivity values.Type: ApplicationFiled: August 21, 2023Publication date: April 4, 2024Inventors: Pedram Mohseni, Lalitha Nayak, Michael Suster, Sina Pourang
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Patent number: 11774388Abstract: As one example, an apparatus includes a dielectric microsensor having a microfluidic chamber that includes a capacitive sensing structure. The microfluidic chamber is adapted to receive a volume of a blood sample, and a bioactive agent is adapted to interact with the blood sample, as a sample under test (SUT), within the microfluidic chamber. A transmitter can provide an input radio frequency (RF) signal to the dielectric microsensor, and a receiver can receive an output RF signal from the dielectric microsensor. A computing device is configured to compute dielectric permittivity values for the SUT based on the output RF signal over a time interval in which the dielectric permittivity values are representative of the bioactive agent interacting with the blood sample over the time interval. The computing device is further configured to provide a readout representative of hemostatic dysfunction for the blood sample based on the dielectric permittivity values.Type: GrantFiled: June 29, 2022Date of Patent: October 3, 2023Assignees: CASE WESTERN RESERVE UNIVERSITY, UNIVERSITY HOSPITALS CLEVELAND MEDICAL CENTERInventors: Pedram Mohseni, Lalitha Nayak, Michael Suster, Sina Pourang
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Publication number: 20220326170Abstract: As one example, an apparatus includes a dielectric microsensor having a microfluidic chamber that includes a capacitive sensing structure. The microfluidic chamber is adapted to receive a volume of a blood sample, and a bioactive agent is adapted to interact with the blood sample, as a sample under test (SUT), within the microfluidic chamber. A transmitter can provide an input radio frequency (RF) signal to the dielectric microsensor, and a receiver can receive an output RF signal from the dielectric microsensor. A computing device is configured to compute dielectric permittivity values for the SUT based on the output RF signal over a time interval in which the dielectric permittivity values are representative of the bioactive agent interacting with the blood sample over the time interval. The computing device is further configured to provide a readout representative of hemostatic dysfunction for the blood sample based on the dielectric permittivity values.Type: ApplicationFiled: June 29, 2022Publication date: October 13, 2022Inventors: Pedram Mohseni, Lalitha Nayak, Michael Suster, Sina Pourang
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Patent number: 11408844Abstract: As one example, an apparatus includes a dielectric microsensor comprising a microfluidic chamber that includes a capacitive sensing structure, the microfluidic chamber including a fluid input port to receive a volume of a blood sample. A bioactive agent is disposed within the chamber to interact with the volume of the blood sample received in the microfluidic chamber. A transmitter provides an input radio frequency (RF) signal to an RF input of the dielectric microsensor. A receiver receives an output RF signal from an RF output of the dielectric microsensor. A computing device that computes dielectric permittivity values of the sample that vary over a time interval based on the output RF signal, the computing device to provide an assessment of hemostatic dysfunction and associated coagulopathy based on the dielectric permittivity values.Type: GrantFiled: April 1, 2020Date of Patent: August 9, 2022Assignees: CASE WESTERN RESERVE UNIVERSITY, THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERAN AFFAIRS, UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATIONInventors: Michael Suster, Pedram Mohseni, Anirban Sen Gupta, Matthew David Neal, Ujjal Didar Singh Sekhon, Sanjay Pitamber Ahuja, Sina Pourang, Debnath Maji
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Patent number: 11175252Abstract: As one example, a fluid monitoring apparatus includes a dielectric microsensor that includes a capacitive sensing structure integrated into a microfluidic channel. The microfluidic channel includes a fluid input to receive a sample volume of a sample under test (SUT). A transmitter provides an input radio frequency (RF) signal to an RF input of the microsensor. A receiver receives an output RF signal from the microsensor. A computing device computes dielectric permittivity values of the SUT that vary over a time interval based on the output RF signal. The computing device may determine an indication of platelet count based on the computed dielectric permittivity values over at least a portion of the time interval.Type: GrantFiled: January 22, 2019Date of Patent: November 16, 2021Assignee: CASE WESTERN RESERVE UNIVERSITYInventors: Michael Suster, Pedram Mohseni, Debnath Maji, Umut Gurkan
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Patent number: 11058316Abstract: As one example, a fluid monitoring apparatus includes a dielectric microsensor that includes a capacitive sensing structure integrated into a microfluidic channel. The microfluidic channel includes a fluid input to receive a sample volume of a sample under test (SUT). A transmitter provides an input radio frequency (RF) signal to an RF input of the microsensor. A receiver receives an output RF signal from the microsensor. A computing device computes dielectric permittivity values of the SUT that vary over a time interval based on the output RF signal. The computing device may determine at least one permittivity parameter based on the computed dielectric permittivity values over at least a portion of the time interval.Type: GrantFiled: May 8, 2020Date of Patent: July 13, 2021Assignee: CASE WESTERN RESERVE UNIVERSITYInventors: Michael Suster, Pedram Mohseni, Debnath Maji, Evi Stavrou, Umut Gurkan
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Publication number: 20200405173Abstract: As one example, a fluid monitoring apparatus includes a dielectric microsensor that includes a capacitive sensing structure integrated into a microfluidic channel. The microfluidic channel includes a fluid input to receive a sample volume of a sample under test (SUT). A transmitter provides an input radio frequency (RF) signal to an RF input of the microsensor. A receiver receives an output RF signal from the microsensor. A computing device computes dielectric permittivity values of the SUT that vary over a time interval based on the output RF signal. The computing device may determine at least one permittivity parameter based on the computed dielectric permittivity values over at least a portion of the time interval.Type: ApplicationFiled: May 8, 2020Publication date: December 31, 2020Inventors: Michael Suster, Pedram Mohseni, Debnath Maji, Evi Stavrou, Umut Gurkan
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Publication number: 20200319128Abstract: As one example, an apparatus includes a dielectric microsensor comprising a microfluidic chamber that includes a capacitive sensing structure, the microfluidic chamber including a fluid input port to receive a volume of a blood sample. A bioactive agent is disposed within the chamber to interact with the volume of the blood sample received in the microfluidic chamber. A transmitter provides an input radio frequency (RF) signal to an RF input of the dielectric microsensor. A receiver receives an output RF signal from an RF output of the dielectric microsensor. A computing device that computes dielectric permittivity values of the sample that vary over a time interval based on the output RF signal, the computing device to provide an assessment of hemostatic dysfunction and associated coagulopathy based on the dielectric permittivity values.Type: ApplicationFiled: April 1, 2020Publication date: October 8, 2020Inventors: Michael Suster, Pedram Mohseni, Anirban Sen Gupta, Matthew David Neal, Ujjal Didar Singh Sekhon, Sanjay Pitamber Ahuja, Sina Pourang, Debnath Maji
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Patent number: 10674931Abstract: As one example, a fluid monitoring apparatus includes a dielectric microsensor that includes a capacitive sensing structure integrated into a microfluidic channel. The microfluidic channel includes a fluid input to receive a sample volume of a sample under test (SUT). A transmitter provides an input radio frequency (RF) signal to an RF input of the microsensor. A receiver receives an output RF signal from the microsensor. A computing device computes dielectric permittivity values of the SUT that vary over a time interval based on the output RF signal. The computing device may determine at least one permittivity parameter based on the computed dielectric permittivity values over at least a portion of the time interval.Type: GrantFiled: January 17, 2017Date of Patent: June 9, 2020Assignees: CASE WESTERN RESERVE UNIVERSITY, THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERAN AFFAIRSInventors: Michael Suster, Pedram Mohseni, Debnath Maji, Evi Stavrou, Umut Gurkan
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Publication number: 20190154603Abstract: As one example, a fluid monitoring apparatus includes a dielectric microsensor that includes a capacitive sensing structure integrated into a microfluidic channel. The microfluidic channel includes a fluid input to receive a sample volume of a sample under test (SUT). A transmitter provides an input radio frequency (RF) signal to an RF input of the microsensor. A receiver receives an output RF signal from the microsensor. A computing device computes dielectric permittivity values of the SUT that vary over a time interval based on the output RF signal. The computing device may determine an indication of platelet count based on the computed dielectric permittivity values over at least a portion of the time interval.Type: ApplicationFiled: January 22, 2019Publication date: May 23, 2019Inventors: Michael Suster, Pedram Mohseni, Debnath Maji, Umut Gurkan
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Publication number: 20190029555Abstract: As one example, a fluid monitoring apparatus includes a dielectric microsensor that includes a capacitive sensing structure integrated into a microfluidic channel. The microfluidic channel includes a fluid input to receive a sample volume of a sample under test (SUT). A transmitter provides an input radio frequency (RF) signal to an RF input of the microsensor. A receiver receives an output RF signal from the microsensor. A computing device computes dielectric permittivity values of the SUT that vary over a time interval based on the output RF signal. The computing device may determine at least one permittivity parameter based on the computed dielectric permittivity values over at least a portion of the time interval.Type: ApplicationFiled: January 17, 2017Publication date: January 31, 2019Inventors: Michael Suster, Michael Mohseni, Debnath Maji, Evi Stavrou, Umut Gurkan
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Patent number: 9995701Abstract: A sensor system can be configured to perform dielectric spectroscopy (DS). For example, the system can include a sensor configured to measure dielectric permittivity of a fluid in response to an RF input signal. Associated interface electronics can include a transmitter to drive the sensor with the RF input signal and a receiver to receive and process an RF output signal from the sensor in response to the RF input signal.Type: GrantFiled: June 2, 2015Date of Patent: June 12, 2018Assignee: Case Western Reserve UniversityInventors: Pedram Mohseni, Michael A. Suster, Mehran Bakshiani, Umut Gurkan
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Publication number: 20150346131Abstract: A sensor system can be configured to perform dielectric spectroscopy (DS). For example, the system can include a sensor configured to measure dielectric permittivity of a fluid in response to an RF input signal. Associated interface electronics can include a transmitter to drive the sensor with the RF input signal and a receiver to receive and process an RF output signal from the sensor in response to the RF input signal.Type: ApplicationFiled: June 2, 2015Publication date: December 3, 2015Inventors: Pedram Mohseni, Michael A. Suster, Mehran Bakshiani, Umut Gurkan