Abstract: Technology provided herein relates in part to methods, processes, machines and apparatuses for non-invasive assessment of genetic alterations. In particular, a method is provided for that includes obtaining a set of sequence reads. The sequence reads each include a single molecule barcode (SMB) sequence that is a non-random oligonucleotide sequence. The method further includes assigning the sequence reads to read groups according to a read group signature. The read group signature comprises an SMB sequence and a start and end position of a nucleic acid fragment from the circulating cell free sample nucleic acid. The sequence reads comprising start and end positions and an SMB sequence similar to the read group signature are assigned to a read group. The method further includes generating a consensus for each read group, and determining the presence or absence of a genetic alteration based on the consensus for each read group.

Abstract: A block cave has a draw column height of at least 450 m, a caved volume, a single extraction level and noundercut level, a plurality of drawbells extending upwardly from the extraction level to the caved volume, and a plurality of pillars separating the drawbells and supporting the rock mass above the extraction level. Each drawbell has a drawbell height of at least 25 m. Each drawbell has the following profile when viewed from a direction perpendicular to a drawbell drive in the extraction level: a throat section having opposed parallel side walls extending upwardly from the extraction level, a tapered section above the throat section, and an undercut section above the tapered section.

Abstract: A block cave has a draw column height of at least 450 meters, a caved volume, a single extraction level and no undercut level, a plurality of drawbells extending upwardly from the extraction level to the caved volume, and a plurality of pillars separating the drawbells and supporting the rock mass above the extraction level. Each drawbell has a drawbell height of at least 25 meters. Each drawbell has the following profile when viewed from a direction perpendicular to a drawbell drive in the extraction level: a throat section having opposed parallel side walls extending upwardly from the extraction level, a tapered section above the throat section, and an undercut section above the tapered section.

Abstract: A block cave has a draw column height of at least 450 meters, a caved volume, a single extraction level and no undercut level, a plurality of drawbells extending upwardly from the extraction level to the caved volume, and a plurality of pillars separating the drawbells and supporting the rock mass above the extraction level. Each drawbell has a drawbell height of at least 25 meters. Each drawbell has the following profile when viewed from a direction perpendicular to a drawbell drive in the extraction level: a throat section having opposed parallel side walls extending upwardly from the extraction level, a tapered section above the throat section, and an undercut section above the tapered section.

Abstract: Technology provided herein relates in part to methods, processes, machines and apparatuses for non-invasive assessment of genetic alterations. In particular, a method is provided for that includes obtaining a set of sequence reads. The sequence reads each include a single molecule barcode (SMB) sequence that is a non-random oligonucleotide sequence. The method further includes assigning the sequence reads to read groups according to a read group signature. The read group signature comprises an SMB sequence and a start and end position of a nucleic acid fragment from the circulating cell free sample nucleic acid. The sequence reads comprising start and end positions and an SMB sequence similar to the read group signature are assigned to a read group. The method further includes generating a consensus for each read group, and determining the presence or absence of a genetic alteration based on the consensus for each read group.

Abstract: A seating device for use in a liquid, the seating device including a body having a closed first end, an open second end and a wall running between the closed first end and the open second end, the closed first end and the wall defining a cavity that is accessible through the open second end, the closed first end defining a seating surface having one or more holes formed therethrough, the one or more holes enabling flow of a fluid therethrough as the seating device is submerged in the liquid.

Abstract: The grills of the present disclosure provide several devices and methods for ensuring that cooking platens are level and provide the correct amount of pressure when cooking a food product. In contrast to currently available cooking devices, those of the present disclosure can be automatically leveled on set up, and adjust during or after operation, thus being able to withstand unpredicted events or normal use that may knock the grills out of level.

Abstract: A clamshell grill having a user interface and a processor that executes one or more programs to select an initial cooking recipe for a food product, by determining an actual product thickness of the food product, determining if the actual product thickness of the food product is greater than or less than the cooking recipe's product thickness, and if the actual product thickness of the food product is greater than or less than the cooking recipe's product thickness, then executing a modified cooking recipe to accommodate a change in the actual product thickness during a cooking cycle, wherein the modified cooking recipe adjusts at least one parameter of the initial cooking recipe.

Abstract: A seating device for use in a liquid, the seating device including a body having a closed first end, an open second end and a wall running between the closed first end and the open second end, the closed first end and the wall defining a cavity that is accessible through the open second end, the closed first end defining a seating surface having one or more holes formed therethrough, the one or more holes enabling flow of a fluid therethrough as the seating device is submerged in the liquid.

Abstract: The present application discloses a cable connector for use in attaching an input cable to an actuator in a vehicle braking system.

Abstract: The present invention relates to a device and method for pre-stressing the cable system of a vehicle brake actuating system.

Abstract: A parking brake actuator for a vehicle includes a toothed stationary sector fixed to a mounting structure, a brake lever pivotably mounted to the sector, a pawl mounted to the brake lever for movement between engaged and disengaged positions relative to the teeth, an elongated, substantially rigid release member mounted to the brake lever for movement relative to the brake lever between normal and depressed positions, and a motion-absorbing member connecting the release member to the pawl. When the brake lever is operatively connected to the vehicle brake cable and in a braking position thereof with the pawl in the engaged position thereof, moving the release member to the depressed position thereof without also moving the brake lever in the brake applying direction compresses the motion-absorbing member without moving the pawl from the engaged position thereof.

Abstract: A fairing for the reduction of vortex-induced vibration and the minimization of drag about a substantially cylindrical element immersed in a fluid medium. The fairing also eliminates the galloping phenomenon typically associated with a teardrop-shaped fairing. The fairing having a U-shaped cylindrical shell with opposing edges defining a longitudinal gap and parallel fins extending outwardly from the opposing edges of the shell, the parallel fins being positioned so as to reduce vortex-induced vibration, minimize drag and to eliminate the galloping phenomenon on the cylindrical element.

Abstract: A brake actuating assembly for a vehicle having a brake system is provided. The assembly includes a mounting bracket for mounting the brake actuating assembly to the vehicle, and a pedal arm mounted to the mounting bracket for pivotal movement about a pivot axis. The pedal arm is connectable to the brake system such that movement of the pedal arm in a brake applying direction activates the brake system and movement of the pedal arm in a brake releasing direction de-activates the brake system. An arcuate rack of teeth is connected to the pedal arm, and a pawl that includes a tooth engages the rack. The assembly also includes a spring that has a first end that operatively connected to the pawl, and the second end that is operatively connected to the mounting bracket in an opening that includes a surface extending between a first stop and a second stop.

Abstract: The present application discloses a brake actuator for applying tension to a brake cable. The actuator includes: a mounting bracket; a brake actuator lever mounted for pivotal movement relative to the mounting bracket in brake applying and brake releasing directions; and a cam-and-drum member mounted for rotation relative to relative to the brake actuator lever. The cam-and-drum member is formed as one integral part including a protruding drum portion and a cam portion integral with the drum portion. The present application also discloses a brake actuator with a one-piece cam member.

Abstract: A fairing for the reduction of vortex-induced vibration and the minimization of drag about a substantially cylindrical element immersed in a fluid medium. The fairing also eliminates the galloping phenomenon typically associated with a teardrop-shaped fairing. The fairing having a U-shaped cylindrical shell with opposing edges defining a longitudinal gap and parallel fins extending outwardly from the opposing edges of the shell, the parallel fins being positioned so as to reduce vortex-induced vibration, minimize drag and to eliminate the galloping phenomenon on the cylindrical element. Preferably, the length to diameter ratio of the fins is 1.5 to 2.50.

Abstract: The present invention discloses a vortex induced vibration inhibitor (“VIVI”) comprising a hollow cylindrical housing having an elongated opening defined by locking edges. The housing is operable between an open and a closed position. Connecting assemblies include barbed connector pins received in grooved housings. Connector slots are provided in the connector and receptor housings. Retainer pins provide for release of connecting assemblies. Spacers are provided to limit movement of the housing in relation to the surrounded structure. An alignment stub is provided.

Abstract: A fairing for the reduction of vortex-induced vibration and the minimization of drag about a substantially cylindrical element immersed in a fluid medium. The fairing also eliminates the galloping phenomenon typically associated with a teardrop-shaped fairing. The fairing having a U-shaped cylindrical shell with opposing edges defining a longitudinal gap and parallel fins extending outwardly from the opposing edges of the shell, the parallel fins being positioned so as to reduce vortex-induced vibration, minimize drag and to eliminate the galloping phenomenon on the cylindrical element. Preferably, the length to diameter ratio of the fins is 1.5 to 2.50.

Abstract: A fairing for the reduction of vortex-induced vibration and the minimization of drag about a substantially cylindrical element immersed in a fluid medium. The fairing also eliminates the galloping phenomenon typically associated with a teardrop-shaped fairing. The fairing having a U-shaped cylindrical shell with opposing edges defining a longitudinal gap and parallel fins extending outwardly from the opposing edges of the shell, the parallel fins being positioned so as to reduce vortex-induced vibration, minimize drag and to eliminate the galloping phenomenon on the cylindrical element.