Abstract: A library of replicating entities, each entity comprises a recombinant vector comprising a randomized nucleic acid sequence, having the reading frame structure [NXX]n [CorAA] [NXX]m [NZZ]o, or [NZZ]o [NXX]m [CorAA] [NXX]n. Each NXX is independently a codon encoding for any amino acid except cysteine, CorAA is a codon encoding for cysteine or at least one other amino acid, each NZZ is independently a codon encoding for any amino acid, and n is an integer from 0 to 40, m is an integer from 1 to 20, o is an integer from 1 to 40, and at least 20 percent of CorAA encode for cysteine. The invention further relates to a set of recombinant vectors and to a set of randomized oligonucleotides, each oligonucleotide having said structure, as well as to a method for generating a library of replicating entities and to a method for identifying an amino acid polymer.

Abstract: The invention relates to a compilation comprising at least five different peptides, each peptide comprising at least one sequence element corresponding to an epitope selected from the group consisting of SEQ ID NO.: 1-354, wherein at least five different epitopes are represented. The invention further relates to an in vitro method for determining a patient's immune status to soybean allergens, to a method for detecting at least one soybean allergen in a substance and to a method for determining the allergenicity of a soybean variety. Additionally, the invention relates to a kit comprising at least one composition containing a compound comprising at least five different sequence elements each corresponding to an epitope selected from the group consisting of SEQ ID NO.: 1-354, wherein at least five different epitopes are represented.

Abstract: The invention relates to a method for activating a surface by increasing the hydrophilicity and/or for binding target structures, particularly selected from the group consisting of proteins, cellular proteins, proteins, cells, carbohydrates, peptides and amino acids. It also relates to the use of an oxidoreductase for activating a surface for the mentioned bonds and to corresponding activated surfaces.

Abstract: A library of replicating entities, each entity comprises a recombinant vector comprising a randomized nucleic acid sequence, having the reading frame structure [NXX]n [CorAA] [NXX]m [NZZ]o, or [NZZ]o [NXX]m [CorAA] [NXX]n. Each NXX is independently a codon encoding for any amino acid except cysteine, CorAA is a codon encoding for cysteine or at least one other amino acid, each NZZ is independently a codon encoding for any amino acid, and n is an integer from 0 to 40, m is an integer from 1 to 20, o is an integer from 1 to 40, and at least 20 percent of CorAA encode for cysteine. The invention further relates to a set of recombinant vectors and to a set of randomized oligonucleotides, each oligonucleotide having said structure, as well as to a method for generating a library of replicating entities and to a method for identifying an amino acid polymer.

Abstract: Method for marking a target structure, comprising the following steps: a) providing a compound V that includes at least one dihydroxy- or trihydroxyphenyl group, b) providing a means for converting the dihydroxy- or trihydroxyphenyl group to a quinone group, c) providing a target structure, d) oxidizing the dihydroxy- or trihydroxyphenyl group of the compound V to the quinone group, and e) contacting the compound V with the target structure, so that a covalent bond can be formed, wherein in step e) the compound V is used in a concentration such that the maximum concentration of dihydroxy-, trihydroxyphenyl groups and quinone groups that are introduced by the compound V is ?500 ?M, preferably ?300 ?M, and more preferably ?100 ?M.

Abstract: The invention relates to a method for activating a surface by increasing the hydrophilicity and/or for binding target structures, particularly selected from the group consisting of proteins, cellular proteins, proteins, cells, carbohydrates, peptides and amino acids. It also relates to the use of an oxidoreductase for activating a surface for the mentioned bonds and to corresponding activated surfaces.

Abstract: Method for marking a target structure, comprising the following steps: a) providing a compound V that includes at least one dihydroxy- or trihydroxyphenyl group, b) providing a means for converting the dihydroxy- or trihydroxyphenyl group to a quinone group, c) providing a target structure, d) oxidising the dihydroxy- or trihydroxyphenyl group of the compound V to the quinone group, and e) contacting the compound V with the target structure, so that a covalent bond can be formed, wherein in step e) the compound V is used in a concentration such that the maximum concentration of dihydroxy-, trihydroxyphenyl groups and quinone groups that are introduced by the compound V is ?500 ?M, preferably ?300 ?M, and more preferably ?100 ?M.

Abstract: The invention relates to methods of treatment comprising administering a compound of the general formula (1): to a patient or a healthy individual.

Abstract: The invention relates to methods of treatment comprising administering a compound of the general formula (1): to a patient or a healthy individual.

Abstract: A print request is received at a reusable software component of a server and forwarded to a server application. The server application provides in response to the print request print data to the server's reusable software component, which, in turn, sends a second print request and forwards the print data from an interface of the server's reusable software component to the client. The client receives the second print request and print data at an interface of a reusable software component of the client; and forwards the print data to a spool system of the client in response to the second print request.

Abstract: A compound of general formula (1) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 and R12 are H or methyl, R13, R14, R15 and R16 are H or alkyl, wherein L1 and L2 are linkers selected from single bond, methyl, ethyl, wherein R19, R20 and R21 are H or —CH2X, NT is selected from H, hydroxyl, alkyl, aminoacid, aminoacid analogue, polypeptide and functional group, CT is selected from hydrogen, hydroxyl, alkyl, aminoacid, aminoacid analogue, polypeptide and functional group shows high selectivity and high affinity for MC1-receptors in combination with effective stimulation or inhibiton of cAMP formation in MC1-receptor expressing cells but low affinity for other subtypes of MC-receptors and may be used to treat a wide range of inflammatory conditions. Also disclosed is a DNA molecule and a corresponding vector encoding the compound, a fusion protein comprising a copy of it, a vector comprising DNA encoding the fusion protein, and a pharmaceutical composition comprising the compound.

Abstract: The invention provides a method for modulating the surface characteristics of a device, which is at least temporarily in contact with, a body fluid and/or a body tissue, which is characterized in that the device is coated at least with a ligand that binds at least one of the body's own molecules, wherein the modulation effect is caused substantially by the body's own molecule. The invention thus relies on an auto-protection principle wherein the patient's own substances are used in order to modulate the surface characteristics. Furthermore devices are disclosed which are capable of presenting a modulated surface.

Abstract: The present invention relates to improvements for managing remote function calls and other mechanisms for managing the remote invocation and control of programs. A separation of the request-driven communication work from one broad unstructured bulk of work into at least two separate portions of management is proposed: a dispatching portion and one or more connection portions. Connections are not closed but are reused whenever advantageous, which yields better performance. A standardized interface is set up which is able to be used by a plurality of different requester applications. Thus, a way is found to pass a RFC connection from one application to another, and the same RFC connection can be used by totally independent applications.

Abstract: The present invention relates to improvements for managing remote function calls and other mechanisms for managing the remote invocation and control of programs. A separation of the request-driven communication work from one broad unstructured bulk of work into at least two separate portions of management is proposed: a dispatching portion and one or more connection portions. Connections are not closed but are reused whenever advantageous, which yields better performance. A standardized interface is set up which is able to be used by a plurality of different requester applications. Thus, a way is found to pass a RFC connection from one application to another, and the same RFC connection can be used by totally independent applications.

Abstract: A display tool is used to simplify the display of a plurality of graphical objects on a display screen. The tool allows a user to select from an inventory of fragments which are required to build a figure. These figures can have child and grandchild elements associated with them. Each figure also has a symbol associated with it. On the display device, an overview window is produced on which graphic objects are shown in symbol form. An arbitrary subset of symbols in the overview window is selected by the user and produces a detail window showing graphical objects or symbols corresponding to the subset of symbols in more detail. These graphical objects are displayed using either their fragment form or their symbol form based on a threshold value as to eliminate overcrowding of screen space. Child and grandchild figure can be directly observed in the detail window by zooming into the selected figure.