Abstract: A handheld device includes an electronic instrument and a capacitive power supply for storing and delivering power to the electronic instrument. The capacitive power supply includes at least one capacitor, and an electronic circuit operable to boost a voltage from the capacitor to a higher voltage for use by the electronic instrument. The capacitive power supply can be rapidly recharged. Some configurations include an accelerometer which permits the handheld device to detect movement and perform various operations responsive to detected movement. A dual charging station is also disclosed.

Abstract: A handheld device includes an electronic instrument and a capacitive power supply for storing and delivering power to the electronic instrument. The capacitive power supply includes at least one capacitor, and an electronic circuit operable to boost a voltage from the capacitor to a higher voltage for use by the electronic instrument. The capacitive power supply can be rapidly recharged. Some configurations include an accelerometer which permits the handheld device to detect movement and perform various operations responsive to detected movement. A dual charging station is also disclosed.

Abstract: A handheld device includes an electronic instrument and a capacitive power supply for storing and delivering power to the electronic instrument. The capacitive power supply includes at least one capacitor, and an electronic circuit operable to boost a voltage from the capacitor to a higher voltage for use by the electronic instrument. The capacitive power supply can be rapidly recharged. Some configurations include an accelerometer which permits the handheld device to detect movement and perform various operations responsive to detected movement. A dual charging station is also disclosed.

Abstract: An examination system having separate enabled interchangeable operating modes includes at least one medical device having a housing retaining an optical system. The examination system further includes an adapter that is configured for aligning a plurality of disparate smart devices with the optical system of the medical device when the adapter is attached to the medical device, thereby enabling multiple operating modes without modification to the device. In at least one version, common engagement features are provided on a plurality of medical devices to permit the adapter and an attached smart device to be used therewith interchangeably.

Abstract: Liposome-based mucus-penetrating particles (MPP) capable of loading hydrophilic agents including therapeutic, prophylactic and diagnostic agents such as the diaCEST MRI contrast agent barbituric acid (BA) were evaluated to determine how to optimize delivery. Polyethylene glycol (PEG)-coated liposomes containing ?7 mol % PEG diffused only approximately 10-fold slower in human cervicovaginal mucus (CVM) compared to their theoretical speeds in water. 7 mol %-PEG liposomes provided improved vaginal distribution compared to 0 and 3 mol %-PEG liposomes.

Abstract: A vaginal speculum apparatus includes a portable illumination assembly that is releasably attached to one of the upper blade and lower blade of a disposable vaginal speculum. The portable illumination assembly is defined by a housing that retains at least one LED and a portable power supply. The portable illumination assembly can be energized by an externally accessible member after the illuminator has been attached to the speculum.

Abstract: A speculum includes a first blade member and a second blade member, each of the first and second blade members having a distal end and an opposing proximal end. A portable illuminator having a light source and at least one battery includes a switch that is accessible through a slit or similar feature in the speculum. According to at least one version, the switch includes an extending tab portion that can extend through the slit or the end of a handle portion of the speculum to enable illumination. In another version, the portable illuminator can be attached to an articulation mechanism that is configured for moving the first and second blade members in relation to one another.

Abstract: A speculum includes a first blade member and a second blade member, each of the first and second blade members having a distal end and an opposing proximal end. A portable illuminator having a light source and at least one battery includes a switch that is accessible through a slit or similar feature in the speculum. According to at least one version, the switch includes an extending tab portion that can extend through the slit or the end of a handle portion of the speculum to enable illumination. In another version, the portable illuminator can be attached to an articulation mechanism that is configured for moving the first and second blade members in relation to one another.

Abstract: A wall console device for controlling a door operator includes a door operator control circuit that transmits signals to at least one door operator, where the at least one door operator operable to move a motorized door. A control pad includes plural touch responsive command selectors and a door operator control means for user control over the opening and closing of the motorized door. The plural command selectors provide input signals to the door operator control circuit and include a command selector to indicate an operating function among a plurality of selectable operating functions, a command selector to select the indicated operating function, and a command selector to cancel the selected operating function. Plural visual indicators assist a user of the wall console device to program the wall console device to control the at least one door operator.

Abstract: A vaginal speculum apparatus includes a portable illumination assembly that is releasably attached to one of the upper blade and lower blade of a disposable vaginal speculum. The portable illumination assembly is defined by a housing that retains at least one LED and a portable power supply. The portable illumination assembly can be energized by an externally accessible member after the illuminator has been attached to the speculum.

Abstract: The present invention provides a novel approach for CEST MR imaging, called Multi-echo Length and Offset VARied Saturation (Me-LOVARS) CEST. This method allows efficient collection of additional CEST data without penalty in scan time, which could be useful for enhancing the contrast, increasing the specificity or improving quantification of exchange. As CEST-MRI has shown promise at both the pre-clinical and clinical levels, including for detecting and grading brain tumors and evaluating ischemia, using either endogenous CEST contrast or through administration of CEST contrast agents. This fast and robust imaging method is suitable for accelerating image collection and widening the scope of applications for CEST-MRI.

Abstract: A handheld diagnostic instrument includes a handle and an instrument head associated with the handle. An innerformer is disposed in an inner cavity of the instrument head in which the instrument head further includes a tab holder. A cushion member is disposed within the housing between the innerformer and the interior of the instrument head. Further, a lens is attached to the instrument head, the lens including a lens tab. A seal is formed between the lens and the innerformer when the lens tab is engaged with the tab holder wherein the cushion member acts to bias the innerformer to maintain the defined seal.

Abstract: A vaginal speculum apparatus includes a portable illumination assembly that is releasably attached to one of the upper blade and lower blade of a disposable vaginal speculum. The portable illumination assembly is defined by a housing that retains at least one LED and a portable power supply. The portable illumination assembly can be energized by an externally accessible member after the illuminator has been attached to the speculum.

Abstract: Systems and apparatuses directed to cartons with user selectable dispensing configurations. An example carton for dispensing a plurality of products stored therein includes a first removable feature configured to be selectively removed from a top surface to enable removal of a portion of a first end; a second removable feature configured to be selectively removed from the top surface to enable removal of a portion of a second end; and a third removable feature configured to be selectively removed from the top surface to enable removal of a portion of the top surface. The carton defines a closed configuration and a dispensing configuration that is defined by at least one of the portion of the first end being removed, the portion of the second end being removed, or the portion of the top surface being removed. Methods for manufacturing a carton with user selectable dispensing configurations are also contemplated.

Abstract: The present invention provides novel hydrogels through peptides, which are designed to self-assemble and produce magnetic resonance (MR) contrast through chemical exchange saturation transfer (CEST). The location and integrity of these gels could consequently be tracked using MR imaging. The self-assembly of the peptides into hydrogels can be brought about by a change in pH, ionic strength, temperature, and concentration of ions.

Abstract: An illumination device for a speculum may include a first housing part and a second housing part that define a cavity therein. The illumination device may further include a pull tab configured to move from a first position to a second position. When the pull tab moves from the first position to the second position, the pull tab may be disposed so as to allow an electric circuit to be complete so as to provide illumination from an illumination source. When the pull tab is disposed in the first position, the pull tab may be positioned to interrupt the electric circuit such that the illumination device is in an unilluminated state.

Abstract: A method for magnetic resonance (MR) imaging or spectroscopy on a MR scanner to detect tissue physiological parameters in one or more tissue areas in a human or non-human subject includes administering to the subject a contrast enhancing physiologically tolerable amount of a sugar that is non-labeled, subjecting the subject to an MR procedure capable of generating MR signals encoding at least one tissue area in the subject in which the sugar either passes or is taken up, detecting a temporal variation in the MR signals in the at least one tissue area after the administering the sugar, determining at least one tissue-related parameter from the temporal variation, and ascertaining whether the at least one tissue-related parameter is abnormal.