Patents by Inventor Michael T. Milbocker
Michael T. Milbocker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11678976Abstract: A device and method for forming an adaptive optic in the capsule of a human eye is disclosed, comprising a capsular interface enclosing an optically acceptable medium. The device establishes a physiologic range of optical power in response to a range of ciliary contractile states. The preferred bi-phasic medium of the device is comprised of a solid three dimensional polymeric network suspended in a liquid aqueous phase and bonded to a capsular interface. The polymeric network provides shape to the capsular interface, optical power, and a physiologic response to the suspensory ligament. The three dimensional network of the bi-phasic medium mimics the stacked fiber configuration and elasticity of a natural lens. An alternative embodiment utilizing a single phase medium is also disclosed with associated structural features provided in the capsular interface.Type: GrantFiled: May 6, 2019Date of Patent: June 20, 2023Assignee: Adaptilens, LLCInventors: Liane Clamen, Paul Glazer, Michael T. Milbocker
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Patent number: 11123364Abstract: A medical composition and devices made from the composition for the delivery of extracts obtained from Boswellia genus, similar compounds synthetically derived, and in particular derivatives of triterpenes is disclosed. The medical device may be implantable, or alternatively a device which contacts the interior of a mammalian body. The medical device may be comprised, of or present an absorbable component containing Boswellia derivatives, or an eluting component. When administered into a particular body site, the Boswellia component may be released substantially and immediately, released slowly, or not released, into the body and residing actively on the medical device surface.Type: GrantFiled: June 21, 2012Date of Patent: September 21, 2021Assignee: BVW Holding AGInventors: Michael T. Milbocker, Lukas von Bluecher
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Publication number: 20190321163Abstract: A device and method for forming an adaptive optic in the capsule of a human eye is disclosed, comprising a capsular interface enclosing an optically acceptable medium. The device establishes a physiologic range of optical power in response to a range of ciliary contractile states. The preferred bi-phasic medium of the device is comprised of a solid three dimensional polymeric network suspended in a liquid aqueous phase and bonded to a capsular interface. The polymeric network provides shape to the capsular interface, optical power, and a physiologic response to the suspensory ligament. The three dimensional network of the bi-phasic medium mimics the stacked fiber configuration and elasticity of a natural lens. An alternative embodiment utilizing a single phase medium is also disclosed with associated structural features provided in the capsular interface.Type: ApplicationFiled: May 6, 2019Publication date: October 24, 2019Inventors: Liane Clamen, Paul Glazer, Michael T. Milbocker
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Patent number: 10278810Abstract: A device and method for forming an adaptive optic in the capsule of a human eye is disclosed, comprising a capsular interface enclosing an optically acceptable medium. The device establishes a physiologic range of optical power in response to a range of ciliary contractile states. The preferred bi-phasic medium of the device is comprised of a solid three dimensional polymeric network suspended in a liquid aqueous phase and bonded to a capsular interface. The polymeric network provides shape to the capsular interface, optical power, and a physiologic response to the suspensory ligament. The three dimensional network of the bi-phasic medium mimics the stacked fiber configuration and elasticity of a natural lens. An alternative embodiment utilizing a single phase medium is also disclosed with associated structural features provided in the capsular interface.Type: GrantFiled: April 28, 2011Date of Patent: May 7, 2019Assignee: OJO, LLCInventors: Liane Clamen, Paul Glazer, Michael T. Milbocker
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Publication number: 20160243272Abstract: The present invention provides a liquid polymer composition which can be implanted into a living mammal and which forms a solid hydrogel by in situ polymerization upon contact with body fluid and tissue. The composition also can be used as a coating on a medical device, or for the formation of a medical device. Formation of a solid implant or coating involves crosslinking of the adhesive with itself and with surrounding tissue. The liquid implant, by itself or in conjunction with various prostheses, can be used for many purposed, including fixation of the urethra for providing treatment for incontinence, and repair of herniations in the abdominal cavity, including rectocele, cystocele, enterocele, and inguinal hernia. The adhesive may be used to establish adhesion prevention during such repairs, in part by coating or being the material of a repair mesh.Type: ApplicationFiled: May 3, 2016Publication date: August 25, 2016Applicant: Promethean Surgical Devices, LLCInventors: Michael T. MILBOCKER, Dix P. POPPAS
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Patent number: 9339583Abstract: A biocompatible tissue-bonding adhesive composition having a polyol of functionality N. The polyol being terminated has at least one polyisocyanate in solution with at least (N?1)% of the solution having free polyisocyanate. N may be in the range 1.5-8. The polyol may be a branched polypropylene/polyethylene oxide copolymer.Type: GrantFiled: July 3, 2013Date of Patent: May 17, 2016Assignee: Promethean Surgical Devices, LLCInventor: Michael T. Milbocker
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Patent number: 9079034Abstract: Electrical stimulation to cardiac tissue stabilizes atrial and ventricular arrhythmia when timed to stabilize a limit cycle structure in a Poincare map. Disclosed are methods and apparatus, operational internally or externally, for removing the reentrant effects of heterogeneity present in a diseased heart and returning the heart to an improved metabolic status allowing removal of support. The methods and apparatus disclosed are also useful in the chronic surveillance and maintenance of regularized contractility in an aged or diseased heart.Type: GrantFiled: May 2, 2013Date of Patent: July 14, 2015Inventor: Michael T. Milbocker
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Patent number: 9050388Abstract: A biocompatible tissue-bonding adhesive composition having a polyol of functionality N. The polyol being terminated has at least one polyisocyanate in solution with at least (N?1)% of the solution having free polyisocyanate. N may be in the range 1.5-8. The polyol may be a branched polypropylene/polyethylene oxide copolymer.Type: GrantFiled: July 3, 2013Date of Patent: June 9, 2015Assignee: Promethean Surgical Devices, LLCInventor: Michael T. Milbocker
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Patent number: 8869802Abstract: Disclosed herein are methods for treating a defect in a spinal disc nuclear space, comprising: (a) creating an opening by open, percutaneous or laparoscopic techniques to access the defect in the nuclear space; (b) removing a desired amount of tissue from the nuclear space; (c) positioning a delivery catheter through the opening; (d) fluidically isolating the nuclear space by blocking the opening with a blocking component of the catheter; (e) delivering an in-situ curable liquid material through a lumen of the catheter to the nuclear space; and (f) maintaining the isolating until the liquid material has cured. Also disclosed are treatment systems and materials for prostheses.Type: GrantFiled: April 14, 2011Date of Patent: October 28, 2014Assignee: Promethean Surgical Devices, LLCInventors: Jeffrey A. Wilson, Michael T. Milbocker, Robert M. Arcangeli
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Publication number: 20140301971Abstract: A medical composition and devices made from the composition for the delivery of extracts obtained from Boswellia genus, similar compounds synthetically derived, and in particular derivatives of triterpenes is disclosed. The medical device may be implantable, or alternatively a device which contacts the interior of a mammalian body. The medical device may be comprised, of or present an absorbable component containing Boswellia derivatives, or an eluting component. When administered into a particular body site, the Boswellia component may be released substantially and immediately, released slowly, or not released, into the body and residing actively on the medical device surface.Type: ApplicationFiled: June 21, 2012Publication date: October 9, 2014Inventors: Michael T. Milbocker, Lukas von Bluecher
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Publication number: 20140288582Abstract: An implantable medical device for providing structural support to tissue is described wherein the implant adheres to tissue without the benefit of suture, surgical adhesive and the like. The adherent or localization means is a hemostat or protein polymerizing materials such as oxidized cellulose, alpha cellulose, polyanhydroglucuronic acid and the like. The structure of the hemostat may be fibular (hallow and solid), woven, particulate, and the structure of hemostats in general. These protein polymerization compounds are beneficially attach to at least one side of a planar implant such as a surgical repair mesh, surgical barrier, and any implantable device intended to isolate or strength a layer of mammalian tissue.Type: ApplicationFiled: June 21, 2012Publication date: September 25, 2014Applicant: BVW HOLDING AGInventors: Michael T. Milbocker, Lukas von Bluecher
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Patent number: 8604099Abstract: The present invention relates to a hydrated, biocompatible tissue-augmentation compound and methodology for its implantation into mammalian tissue. The tissue-augmentation compound is comprised of: living tissue, optionally body derived fluids, and at least one NCO-terminated hydrophilic urethane prepolymer derived from an organic polyisocyanate, and oxyethylene-containing diols or polyols in which essentially all of hydroxyl groups are capped with polyisocyanate.Type: GrantFiled: March 16, 2012Date of Patent: December 10, 2013Assignee: Promethean Surgical DevicesInventor: Michael T. Milbocker
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Publication number: 20130296959Abstract: Electrical stimulation to cardiac tissue stabilizes atrial and ventricular arrhythmia when timed to stabilize a limit cycle structure in a Poincare map. Disclosed are methods and apparatus, operational internally or externally, for removing the reentrant effects of heterogeneity present in a diseased heart and returning the heart to an improved metabolic status allowing removal of support. The methods and apparatus disclosed are also useful in the chronic surveillance and maintenance of regularized contractility in an aged or diseased heart.Type: ApplicationFiled: May 2, 2013Publication date: November 7, 2013Applicant: Technology Innovation, LLCInventor: Michael T. Milbocker
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Publication number: 20130296460Abstract: A biocompatible tissue-bonding adhesive composition having a polyol of functionality N. The polyol being terminated has at least one polyisocyanate in solution with at least (N?1)% of the solution having free polyisocyanate. N may be in the range 1.5-8. The polyol may be a branched polypropylene/polyethylene oxide copolymer.Type: ApplicationFiled: July 3, 2013Publication date: November 7, 2013Applicant: Promethean Surgical Devices, LLCInventor: Michael T. Milbocker
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Publication number: 20130295037Abstract: A biocompatible tissue-bonding adhesive composition having a polyol of functionality N. The polyol being terminated has at least one polyisocyanate in solution with at least (N?1) % of the solution having free polyisocyanate. N may be in the range 1.5-8. The polyol may be a branched polypropylene/polyethylene oxide copolymer.Type: ApplicationFiled: July 3, 2013Publication date: November 7, 2013Applicant: PrometheanSurgical Devices, LLCInventor: Michael T. Milbocker
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Publication number: 20130035415Abstract: The present invention relates to a hydrated, biocompatible tissue-augmentation compound and methodology for its implantation into mammalian tissue. The tissue-augmentation compound is comprised of: living tissue, optionally body derived fluids, and at least one NCO-terminated hydrophilic urethane prepolymer derived from an organic polyisocyanate, and oxyethylene-containing diols or polyols in which essentially all of hydroxyl groups are capped with polyisocyanate.Type: ApplicationFiled: March 16, 2012Publication date: February 7, 2013Applicant: PROMETHEAN SURGICAL DEVICESInventor: Michael T. Milbocker
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Publication number: 20120179176Abstract: The present invention relates to a composite prosthesis including a coated mesh having at least one opening through a first surface and a second surface of the coated mesh; the coated mesh comprising a mesh and a biocompatible coating substantially surrounding each filament of the mesh, wherein the biocompatible coating is formed by coating the mesh with a polyol prepolymer and curing the prepolymer, the prepolymer comprising a polyalkylene oxide polyol end capped with isocyanate, the polyalkylene oxide polyol having from about 70% to about 95% ethylene oxide groups and the remainder propylene oxide; and a barrier material comprising a biocompatible membrane constructed and arranged to cover at least one surface of the coated mesh, wherein the barrier material comprises a biologic material.Type: ApplicationFiled: December 27, 2011Publication date: July 12, 2012Applicant: PROMETHEAN SURGICAL DEVICES, LLCInventors: Jeffrey A. Wilson, Michael T. Milbocker
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Publication number: 20120039959Abstract: Described are mono- and bi-layer alginate post-surgical anti-adhesion barriers with tailored absorption profiles and non-migrating characteristics. Muco-adhesive properties of alginates in their solid state are used to localize the device, and lubricious properties of alginates in their liquid state are used to mitigate adhesion formation during wound healing. In addition, the design of the implant can be selected such that the crosslinking agent is released from the device under specific conditions and the absorbance profile modified. A medicinal agent may optionally be incorporated.Type: ApplicationFiled: August 16, 2011Publication date: February 16, 2012Inventors: Joerg TESSMAR, Eva Esser, Thomas Reintjes, Lukas Bluecher, Michael T. Milbocker
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Patent number: 8114157Abstract: A new reversibly gelling polyurethane (RGP) polymer composition is described, as well as novel processes for its preparation, and its medical uses for filling spaces in tissue, or bulking tissue, or for restoring organ function. The novel RGP polymer forms a gel on standing, liquefies during shear and reversibly reforms a macroscopic gel on standing after being sheared. Methods of use include delivering the improved gel to a site on the body to fill voids or to augment local tissue bulk.Type: GrantFiled: January 24, 2007Date of Patent: February 14, 2012Assignee: Promethean Surgical Devices, LLCInventors: Michael T. Milbocker, Jeffrey A. Wilson
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Publication number: 20120010726Abstract: Described are devices and methods for reinforcing a layer of living tissue, which when affixed to a tissue layer prior to surgical incision, reinforces the tissue to be incised, provides a fibro-conductive matrix to promote healing in a preferred plane, and provides for a subsequent closure and fluidic seal. A partially or entirely absorbable growth matrix is disclosed, comprising two adhesion-resistant layers enclosing a cellular conductive medium for promoting fibrosis in a preferred plane. The cellular conductive portion is partially or entirely sequestered from surrounding tissue. The device is constructed in a physiologic range of tensile strengths and elasticity suitable for closure of the pericardium, peritoneum, or other typically thin membranes enclosing organs in the body, whose function is to prevent adhesions between tissue surfaces normally in motion.Type: ApplicationFiled: June 9, 2011Publication date: January 12, 2012Inventors: Lukas BLUECHER, Michael T. Milbocker, Christopher J. Calhoun