Abstract: The disclosure relates to barcoded polymer nanoparticles for in vivo screening and for in vivo therapeutic delivery, and methods therefor. More particularly, the invention relates to polymer nanoparticles, such as reversible addition-fragmentation chain transfer (RAFT) polymer compositions, associated with polynucleotide barcodes, for therapeutic delivery, and for high throughput in vivo screening of drug delivery nanoparticles.

Abstract: The invention relates to barcoded nucleic acid nanostructure delivery compositions for in vivo screening for subsequent use in vivo therapeutic delivery, and methods therefor. More particularly, the invention relates to nucleic acid nanostructure delivery compositions, such as DNA origami structures, associated with barcodes for high throughput in vivo screening of the nucleic acid nanostructure delivery compositions for subsequent use in drug delivery, and methods therefor.

Abstract: A surgical stapler, or fastening instrument, may generally comprise a layer, such as a tissue thickness compensator, for example, releasably attached to a fastener cartridge and/or anvil by a flowable attachment portion. The flowable attachment portion may be indefinitely flowable. The flowable attachment portion may be flowable from the time that layer is installed to the fastener cartridge to the time in which the layer is implanted to patient tissue. The flowable attachment portion may comprise a pressure sensitive adhesive. The flowable attachment portion may comprise an adhesive laminate comprising a base layer comprising the tissue thickness compensator and an adhesive layer on at least a portion of a surface of the base layer comprising the pressure sensitive adhesive. Articles of manufacture comprising flowable attachment portion and methods of making and using the flowable attachment portion are also described.

Abstract: A system and method for a user-centric decentralized digital communication platform aggregating multiple user groups within a defined organization, community or affiliated networks enables secure data transfer of complex multi-party data across multiple information systems, organizations, communities, and external affiliates. A comprehensive digital ecosystem, in which varied user groups within specific industries can identify, interact and manage everyday tasks and requests, provides an intuitive networking communication platform that can utilize distributed ledger technology to reward participation and exchange. The computer-implementable communication platform system is operable in combination with multiple information systems, and includes or provides a central remote abstraction layer, service or system for enabling inter-information system operations, and a single interface for client-to-information system interactions.

Abstract: A system and method for a user-centric decentralized digital communication platform aggregating multiple user groups within a defined organization, community or affiliated networks enables secure data transfer of complex multi-party data across multiple information systems, organizations, communities, and external affiliates. A comprehensive digital ecosystem, in which varied user groups within specific industries can identify, interact and manage everyday tasks and requests, provides an intuitive networking communication platform that can utilize distributed ledger technology to reward participation and exchange. The computer-implementable communication platform system is operable in combination with multiple information systems, and includes or provides a central remote abstraction layer, service or system for enabling inter-information system operations, and a single interface for client-to-information system interactions.

Abstract: A method and system provides efficient data searches. The method and system include receiving search request data that requests a search to be made and identifying multiple search terms or clauses in the search request data. The method and system includes determining an expected cost in resources for searching each search term. The method and system then searches for each search term in order from least resource intensive to most resource intensive, with each search after the first search being performed only among the results of the previously searched term.

Abstract: A method and system provides efficient data searches. The method and system include receiving search request data that requests a search to be made and identifying multiple search terms or clauses in the search request data. The method and system includes determining an expected cost in resources for searching each search term. The method and system then searches for each search term in order from least resource intensive to most resource intensive, with each search after the first search being performed only among the results of the previously searched term(s).

Abstract: One embodiment of the present invention provides a system for automatically modifying computer parameters as an incentive for complying with data policies. During operation, the system receives, at a computing system, a data policy definition, wherein the data policy definition comprises: one or more metrics associated with data usage, and one or more desired vectors associated with the one or more metrics. Next, the system receives, at the computing system, usage statistics for data, wherein the usage statistics comprise the one or more metrics for one or more clients. The system then analyzes the usage statistics to determine, at the computing system, a first score indicating how a first client in the one or more clients is performing compared to the one or more desired vectors for the one or more metrics. Finally, the system automatically modifies a parameter of the computing system associated with the first client based on the first score.

Abstract: One embodiment of the present invention provides a system for distributing an access control service to local nodes. During operation, the system receives, at a node in a network, a policy file comprising access policies for resources in the network, wherein the access policies are associated with attributes of profiles, and wherein the profiles are associated with clients. Next, the system compiles, at the node, the policy file into an optimized data structure. Finally, the system stores, at the node, the optimized data structure in memory to facilitate subsequent local lookups of permissions associated with the attributes and the resources.

Abstract: An information handling system includes a central processing unit, a temperature sensor to provide temperature information, a humidity sensor to provide humidity information, and an embedded controller. The embedded controller determines a current dew point temperature based on the temperature information and the humidity information. The embedded controller activates a condensation mitigation procedure if a difference between a current temperature and the current dew point temperature is less than a threshold value stored at a register at the embedded controller. The mitigation procedure is a software program executed by the information handling system.

Abstract: An on-board spool-able re-useable containment boom for a waterborne vessel that lies substantially flat and capable of being spooled when deflated and floats in the proper orientation when inflated, that has spool-able re-inflatable float sections which are sequentially inflated during deployment and sequentially deflated during recovery, that can be repeatedly deployed and recovered for the purposes of training and testing, and that can be deployed immediately upon occurrence of an oil spill from a waterborne vessel because of its on-board location and its rapid deployment, and a control system for proper inflation and deflation of spool-able re-useable containment boom during deployment and recovery.

Abstract: An on-board re-inflatable containment boom for a waterborne vessel that lies substantially flat and capable of being spooled when deflated and floats in the proper orientation when inflated, that has re-inflatable float sections which are sequentially inflated during deployment and sequentially deflated during recovery, that can be repeatedly deployed and recovered for the purposes of training and testing, and that can be deployed immediately upon occurrence of an oil spill from a waterborne vessel because of its on-board location and its rapid deployment, and a control system for proper inflation and deflation of re-inflatable containment boom during deployment and recovery.

Abstract: An information handling system is disclosed. The information handling system may include a chassis and a storage resource assembly. The storage resource assembly may include a bezel coupled to the chassis by a first connector, the bezel configured to couple to a storage resource by a second connector and a shock isolation cap configured to couple to the storage resource, the shock isolation cap comprising a proximal end proximate to the bezel and a distal end opposite the proximal end.

Abstract: An on-board re-inflatable containment boom for a waterborne vessel that lies substantially flat and capable of being spooled when deflated and floats in the proper orientation when inflated, that has re-inflatable float sections which are sequentially inflated during deployment and sequentially deflated during recovery, that can be repeatedly deployed and recovered for the purposes of training and testing, and that can be deployed immediately upon occurrence of an oil spill from a waterborne vessel because of its on-board location and its rapid deployment, and a control system for proper inflation and deflation of re-inflatable containment boom during deployment and recovery.

Abstract: One embodiment of the present invention provides a system for automatically modifying computer parameters as an incentive for complying with data policies. During operation, the system receives, at a computing system, a data policy definition, wherein the data policy definition comprises: one or more metrics associated with data usage, and one or more desired vectors associated with the one or more metrics. Next, the system receives, at the computing system, usage statistics for data, wherein the usage statistics comprise the one or more metrics for one or more clients. The system then analyzes the usage statistics to determine, at the computing system, a first score indicating how a first client in the one or more clients is performing compared to the one or more desired vectors for the one or more metrics. Finally, the system automatically modifies a parameter of the computing system associated with the first client based on the first score.

Abstract: An information handling system includes a central processing unit, a temperature sensor to provide temperature information, a humidity sensor to provide humidity information, and an embedded controller. The embedded controller determines a current dew point temperature based on the temperature information and the humidity information. The embedded controller activates a condensation mitigation procedure if a difference between a current temperature and the current dew point temperature is less than a threshold value stored at a register at the embedded controller. The mitigation procedure is a software program executed by the information handling system.

Abstract: An on-board re-inflatable containment boom system for a waterborne vessel providing an on-board re-inflatable containment boom that lies substantially flat and capable of being spooled when deflated and floats in the proper orientation when inflated, that has re-inflatable float sections which are sequentially inflated during deployment and sequentially deflated during recovery, that can be repeatedly deployed and recovered for the purposes of training and testing, and that can be deployed immediately upon occurrence of an oil spill from a waterborne vessel because of its on-board location and its rapid deployment, providing controlled inflation and deflation during deployment and recovery, and a method for containment of an oil spill from a waterborne vessel using an on-board re-inflatable containment boom system.