Abstract: The present disclosure relates generally to compounds that bind to and act as degraders of an IKAROS Family Zinc Finger (IKZF) protein, such as IKZF2 (Helios) and/or IKZF4 (Eos). The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding and degradation of an IKZF protein, such as IKZF2 and/or IKZF4, including cancer.

Abstract: A computer-implemented method is provided, for retrieving data and metadata according to a data harvesting criteria into an indexed repository, comprising providing a user interface allowing a user to define data harvesting criteria for adjusting a subset of data and metadata on an indexed repository. Responsive to a user utilizing the user interface by defining the data harvesting criteria, the subset of data and metadata on the indexed repository is adjusted according to the data harvesting criteria.

Abstract: A computer-implemented method is provided, for retrieving data and metadata according to a data harvesting criteria into an indexed repository, comprising providing a user interface allowing a user to define data harvesting criteria for adjusting a subset of data and metadata on an indexed repository. Responsive to a user utilizing the user interface by defining the data harvesting criteria, the subset of data and metadata on the indexed repository is adjusted according to the data harvesting criteria.

Abstract: A computer-implemented method is provided, for retrieving data and metadata according to a data harvesting criteria into an indexed repository, comprising providing a user interface allowing a user to define data harvesting criteria for adjusting a subset of data and metadata on an indexed repository. Responsive to a user utilizing the user interface by defining the data harvesting criteria, the subset of data and metadata on the indexed repository is adjusted according to the data harvesting criteria.

Abstract: A computer-implemented method is provided, for retrieving data and metadata according to a data harvesting criteria into an indexed repository, comprising providing a user interface allowing a user to define data harvesting criteria for adjusting a subset of data and metadata on an indexed repository. Responsive to a user utilizing the user interface by defining the data harvesting criteria, the subset of data and metadata on the indexed repository is adjusted according to the data harvesting criteria.

Abstract: A computer-implemented method is provided, for retrieving data and metadata according to a data harvesting criteria into an indexed repository, comprising providing a user interface allowing a user to define data harvesting criteria for adjusting a subset of data and metadata on an indexed repository. Responsive to a user utilizing the user interface by defining the data harvesting criteria, the subset of data and metadata on the indexed repository is adjusted according to the data harvesting criteria.

Abstract: A self-tapping sleeve for providing a ceiling junction for a suspended lighting fixture has a cylindrical body, a center passageway for containing the junction, a thread structure on the perimeter surface of the cylindrical body, and two perimeter cutting elements at the top end of the cylindrical body for producing a circular cutting action in front of the sleeve when the sleeve is rotated in and advance rotation. A trim ring is additionally provided at the bottom end of the body to trim out the ceiling junction when the sleeve is installed. A key-shaped portion of the center passageway receives the key-shaped end of a drive tool used to install the sleeve.

Abstract: A ballast holder which can be fabricated from a single piece of bent sheet metal material, includes a gusseted riser structure, a base portion extending rearwardly from the foot of the riser structure, and a top flange portion extending in a forwardly direction from the top end of the riser structure for securing one of the mounting flanges of a ballast. The height of the rigid riser structure is chosen to be at least as great as the maximum height of a standard ballast to be held thereby. The ballast holder is used to install a ballast in an inverted position within a lighting fixture housing and can accommodate different sized ballasts. The ballast holder also reduces the amount of structure between the ballast and the overlying reflector element of the lighting fixture and thereby reduces the tendency of the ballast holding structure to bow or distort the lighting fixture's reflector where space is limited.