Abstract: A system for modularly assembling a scope device includes an optical module which has an optical housing and a longitudinal member extending distally therefrom. A distal end of the member includes a camera for visualizing a target area, electric wires and a light source extending from the camera to the optical housing. The system also includes a deflector module coupleable with the optical module. The deflector module includes a deflector housing and a deflector shaft extending distally therefrom. The shaft includes a first channel sized, shaped and configured to receive the member therein and a deflectable portion extending along a distal portion of the shaft. The deflector housing includes an actuator for deflecting the deflectable portion, the optical and deflector housings including corresponding connecting elements to engage one another when the member is inserted through the first channel and the deflector and optical housings are coupled.

Abstract: A push gateway brokers messages between backend services and client devices connected to the gateway. The gateway includes a plurality of messaging frontend servers, a messaging database, and a plurality of topic servers. The messaging frontend servers manage the socket connections connecting the client devices to the push gateway. The messaging frontend servers may further monitor the socket connections, collecting analytical data on the client devices and the connections. The messaging database is a key-value database that subscribes messaging frontend servers to topics. The topic servers receive publish requests from the backend servers to identify subscribed messaging frontend servers in the messaging database to push messages out to. The frontend messaging servers subsequently push out the message to the client devices subscribed to the topic.

Abstract: An Image Activated Cell Sorting (IACS) classification workflow includes: employing a neural network-based feature encoder (or extractor) to extract features of cell images; automatically clustering cells based on extracted cell features; identifying a cluster to pick which cluster(s) to sort based on the cell images; fine-tuning a classification network based on the cluster(s) selected; and once refined, the classification network is used to sort cells for real-time live sorting.

Abstract: Methods and apparatus for creating a dual metal interconnect on a substrate. In some embodiments, a first liner of a first nitride material is deposited into at least one 1X feature and at least one wider than 1X feature, the first liner has a thickness of less than or equal to approximately 12 angstroms; a second liner of a first metal material is deposited into the at least one 1X feature and at least one wider than 1X feature; the first metal material is reflowed such that the at least one 1X feature is filled with the first metal material and the at least one wider than 1X feature remains unfilled with the first metal material; a second metal material is deposited on the first metal material, and the second metal material is reflowed such that the at least one wider than 1X feature is filled with the second metal material.

Abstract: This disclosure features chemical entities (e.g., a compound or a pharmaceutically acceptable salt and/or hydrate and/or prodrug of the compound) that modulate (e.g., agonize) the apelin receptor (also referred to herein as the APJ receptor; gene symbol APLNR). This disclosure also features compositions containing the same as well as other methods of using and making the same. The chemical entities are useful, e.g., for treating a subject (e.g., a human) having a disease, disorder, or condition in which a decrease in APJ receptor activity (e.g., repressed or impaired APJ receptor signaling; e.g., repressed or impaired apelin-APJ receptor signaling) or downregulation of endogenous apelin contributes to the pathology and/or symptoms and/or progression of the disease, disorder, or condition.

Abstract: In some examples, a wafer bow measurement system comprises a measurement unit including: a wafer support assembly to impart rotational movement to a measured wafer supported in the measurement unit; an optical sensor; a calibration standard to calibrate the optical sensor; a linear stage actuator to impart linear direction of movement to the optical sensor; a wafer centering sensor to determine a centering of the measured wafer supported in the measurement unit; and a wafer alignment sensor to determine an alignment of the measured wafer supported in the measurement unit.

Abstract: A system may have a support structure that separates an exterior region from an interior region. The system may include a lighting system with interior and/or exterior lights with adjustable diffusers. An interior light may be used as a task light, a cabin light, a sensor indicator light, or a trim light. Adjustments to the adjustable diffusers can be used to adjust the angular spread of emitted light for operation in different lighting modes.

Abstract: A multimedia streaming device can include a first circuit board configured to provide user controls and a second circuit board electrically coupled with the first circuit board and configured to provide content processing. The multimedia streaming device can also include a heat sink positioned between the first circuit board and the second circuit board and defining a speaker enclosure that includes a first portion in contact with the first circuit board, a second portion in contact with the second circuit board, and a third portion. The multimedia streaming device can additionally include a speaker installed in the third portion of the speaker enclosure.

Abstract: Single-stranded oligonucleotide probes, systems, kits and methods for chromosome enumeration, gene copy enumeration, or tissue diagnostics. The probes are particularly suited for detecting gene amplification, deletion, or rearrangement in tissue samples in a single, dual, or multiplexed assay. The probes exhibit improved performance compared to industry leading dual-stranded probes; particularly in terms of the rate of hybridization.

Abstract: A scope device includes a shaft, a deflectable portion, and a handle portion. The shaft is inserted through a body lumen to a target area within a body. The shaft defines first and second lumens extending along a proximal portion thereof. The first and second lumens are merged to form a common lumen along a distal portion thereof via a fitting having a structure which, when connected to the first and second lumens, converge the first and second lumens toward the common lumen. The deflectable portion is connected to the distal end of the shaft and includes a channel aligned with and in communication with the common lumen. The handle portion includes a connector having a first hub including a first channel open to and in communication with the first lumen and a second hub including a second channel open to and in communication with the second lumen.

Abstract: An endoscopic deployment device includes a body mountable on an endoscopic device, a communication interface, and a motor. The body has a movable carrier couplable to an elongated end effector device. The effector device has an end effector shaft covered by an outer sheath and an end effector extending from a distal end of the shaft. The sheath is sized and shaped for insertion through a working channel of an endoscopic shaft of the endoscopic device. The body has a carrier channel sized for the carrier to slide therein. The end effecter is actuatable between open and closed positions by sliding the carrier in the carrier channel which in turn slides the sheath over the end effector shaft to uncover/cover the end effector. Rotation of a drive shaft of the motor is sliding the carrier in the carrier channel and actuating the end effector in response to a signal.

Abstract: A method and system for migrating Extensible Markup Language (XML) schemas between releases of a computing application. The method provides first and second versions of an XML document by the computing application, each version having a different schema. The first version is migrated to the second version using a migration step. The method uses a Dependency injection Framework to abstract the characteristics of the at least one migration step. The method also transforms the first schema to the second schema, based on the abstracted characteristics of the at least one migration step, in such a way that the first version of the XML document is migrated into the second version of the XML document. The method migrates the first version into the second version in such a way that the second version can access application data from the first version.

Abstract: Disclosed herein are systems and methods for implementing change value indication and historical value comparison at a user interface including means for storing records in a database, wherein updates to the records are recorded into a historical trending data object to maintain historical values for the records when the records are updated in the database; receiving input from a user device specifying data to be displayed at the user device; receiving historical filter input from the user device; querying the records stored in the database for the data to be displayed; querying the historical trending data object for the historical values of the data to be displayed; comparing the data to be displayed with the historical values of the data to be displayed to determine one or more changed values corresponding to the data to be displayed; and displaying a change value indication GUI to the user device displaying at least the data to be displayed and a changed value indication based on the one or more changed v

Abstract: A method and system for migrating Extensible Markup Language (XML) schemas between releases of a computing application. The method provides first and second versions of an XML document by the computing application, each version having a different schema. The first version is migrated to the second version using a migration step. The method uses a Dependency injection Framework to abstract the characteristics of the at least one migration step. The method also transforms the first schema to the second schema, based on the abstracted characteristics of the at least one migration step, in such a way that the first version of the XML document is migrated into the second version of the XML document. The method migrates the first version into the second version in such a way that the second version can access application data from the first version.

Abstract: A method and system for migrating Extensible Markup Language (XML) schemas between releases of a computing application. The method provides first and second versions of an XML document by the computing application, each version having a different schema. The first version is migrated to the second version using a migration step. The method uses a Dependency Injection Framework to abstract the characteristics of the at least one migration step. The method also transforms the first schema to the second schema, based on the abstracted characteristics of the at least one migration step, in such a way that the first version of the XML document is migrated into the second version of the XML document. The method migrates the first version into the second version in such a way that the second version can access application data from the first version.

Abstract: Techniques and systems for generating ink effects for an ink stroke are described. In particular, ink gradients for digital ink strokes are provided. The described techniques allow for inking input to be transformed into a structure in which conventional and unconventional graphics techniques can be applied. A digital ink system can receive an ink stroke having ink stroke information. The outline of the ink stroke can be identified, and the ink stroke information can be transformed into surface information within the outline of the ink stroke. A graphic effect can be applied to the ink stroke using the surface information.

Abstract: Automated systems, methods for constructing card multipacks, and a card multipack constructing using the same are provided. An automated system for constructing card multipacks includes: a movable conveyor including a plurality of tooling plates, each configured to receive a height adjusting member; a first carrier placing station configured to place a first carrier portion of a carrier on a tooling plate of the plurality of tooling plates; a first card placing station configured to place a first stored value card on the first carrier portion; a first data capture station configured to read a first card bar code of the first stored value card in-line in the automated system; and a software system adapted to verify the first card bar code with a data file.

Abstract: Techniques and systems for applying an ink effect to the drawing of an ink stroke can include absolute age for a digital ink stroke. A digital ink system can identify a reference time from which to represent a current time. The system can generate an absolute age of each ink point of the ink stroke based on the reference time. Then the ink effect can be applied to the ink stroke with a rhythm derived from when the ink stroke was originally drawn by using the absolute age of each ink point. In some cases, the rhythm can be the same rhythm as when the ink stroke was originally drawn. In other cases, the rhythm can be modified based on the rhythm the ink stroke was originally drawn. For example, the original rhythm may be accelerating, decelerating, skewed, compressed, affine, or non-affine.

Abstract: Systems and methods are provided for user interface date selectors for historical reports. A user interface outputs a date selector including a calculated dates option, wherein the calculated dates option is based on a date frequency applied to a date range. The user interface receives a selection via the date selector. Dates associated with the selection are identified. The user interface outputs the dates as a preview of a historical report, wherein the dates are output in a chronological order.

Abstract: Automated systems, methods for constructing card multipacks, and a card multipack constructing using the same are provided. An automated system for constructing card multipacks includes: a movable conveyor including a plurality of tooling plates, each configured to receive a height adjusting member; a first carrier placing station configured to place a first carrier portion of a carrier on a tooling plate of the plurality of tooling plates; a first card placing station configured to place a first stored value card on the first carrier portion; a first data capture station configured to read a first card bar code of the first stored value card in-line in the automated system; and a software system adapted to verify the first card bar code with a data file.