Patents by Inventor Michael Tay

Michael Tay has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12129506
    Abstract: This invention relates to metabolically engineered microorganism strains, such as bacterial strains, in which there is an increased utilization of malonyl-CoA for production of a fatty acid or fatty acid derived product, wherein the modified microorganism produces fatty acyl-CoA intermediates via a malonyl-CoA dependent but malonyl-ACP independent mechanism.
    Type: Grant
    Filed: June 29, 2022
    Date of Patent: October 29, 2024
    Assignee: CARGILL, INCORPORATED
    Inventors: Michael D. Lynch, Michael Tai Man Louie, Shelley Copley, Eileen Colie Spindler, Brittany Robinson, Matthew Lipscomb, Tanya Lipscomb-Warnecke, Hans H. Liao, David Hogsett, Ron Evans
  • Patent number: 12123045
    Abstract: Genes encoding mutant 3-ketoacyl-CoA synthases are introduced into host cells. Certain of the mutants enhance the production of shorter-chain fatty acids and derivatives by the cell than do the wild-type (unmutated) enzymes. In other cases, the chain length is not significantly affected, but productivity is enhanced. In specific cases, both a shift toward lower chain length and higher productivity is seen. Cells producing the mutant 3-ketoacyl-CoA synthases are especially suitable for producing C6-C10 fatty acids and derivatives.
    Type: Grant
    Filed: May 2, 2022
    Date of Patent: October 22, 2024
    Assignee: CARGILL, INCORPORATED
    Inventors: Hans H. Liao, Catherine Bradshaw Poor, Travis Robert Wolter, Michael Tai Man Louie, Erin Kathleen Marasco, Ana Negrete-Raymond
  • Publication number: 20230203430
    Abstract: The present disclosure provides an engineered microorganism capable of producing malonic acid, malonate, esters of malonic acid, or mixtures thereof. The engineered microorganism includes a malonate-semialdehyde dehydrogenase that is heterologous to a native form of the engineered microorganism and comprises at least 90% sequence identity to any one of SEQ ID Nos: 7, 9, 11, 13, 15, 17, 19, 21, 23, 27, 29, and 31, wherein the engineered microorganism is capable of producing about 9 g/L to about 250 g/L of malonic acid, malonate, esters of malonic acid, or mixtures thereof.
    Type: Application
    Filed: December 21, 2020
    Publication date: June 29, 2023
    Applicant: CARGILL, INCORPORATED
    Inventors: Keith Michael BRADY, Cathy Staloch HASS, Peter Alan JAUERT, Nandita KOHLI, Briana Kristen KOZLOWICZ, Hans H. LIAO, Michael Tai Man LOUIE, Michiel MATTHIJS, Naga Sirisha PARIMI, Catherine Bradshaw POOR, Brian Jeffrey RUSH, Travis Tobert WOLTER
  • Publication number: 20230033275
    Abstract: This invention relates to metabolically engineered microorganism strains, such as bacterial strains, in which there is an increased utilization of malonyl-CoA for production of a fatty acid or fatty acid derived product, wherein the modified microorganism produces fatty acyl-CoA intermediates via a malonyl-CoA dependent but malonyl-ACP independent mechanism.
    Type: Application
    Filed: June 29, 2022
    Publication date: February 2, 2023
    Applicant: CARGILL, INCORPORATED
    Inventors: Michael D. LYNCH, Michael Tai Man LOUIE, Shelley COPLEY, Eileen Colie SPINDLER, Brittany ROBINSON, Matthew LIPSCOMB, Tanya LIPSCOMB-WARNECKE, Hans H. LIAO, David HOGSETT, Ron EVANS
  • Publication number: 20220403425
    Abstract: Genes encoding mutant 3-ketoacyl-CoA synthases are introduced into host cells. Certain of the mutants enhance the production of shorter-chain fatty acids and derivatives by the cell than do the wild-type (unmutated) enzymes. In other cases, the chain length is not significantly affected, but productivity is enhanced. In specific cases, both a shift toward lower chain length and higher productivity is seen. Cells producing the mutant 3-ketoacyl-CoA synthases are especially suitable for producing C6-C10 fatty acids and derivatives.
    Type: Application
    Filed: May 2, 2022
    Publication date: December 22, 2022
    Applicant: CARGILL, INCORPORATED
    Inventors: Hans H. LIAO, Catherine Bradshaw POOR, Travis Robert WOLTER, Michael Tai Man LOUIE, Erin Kathleen MARASCO, Ana NEGRETE-RAYMOND
  • Patent number: 11345938
    Abstract: Genes encoding mutant 3-ketoacyl-CoA synthases are introduced into host cells. Certain of the mutants enhance the production of shorter-chain fatty acids and derivatives by the cell than do the wild-type (unmutated) enzymes. In other cases, the chain length is not significantly affected, but productivity is enhanced. In specific cases, both a shift toward lower chain length and higher productivity is seen. Cells producing the mutant 3-ketoacyl-CoA synthases are especially suitable for producing C6-C10 fatty acids and derivatives.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: May 31, 2022
    Assignee: CARGILL, INCORPORATED
    Inventors: Hans H. Liao, Catherine Bradshaw Poor, Travis Robert Wolter, Michael Tai Man Louie, Erin Kathleen Marasco, Ana Negrete-Raymond
  • Patent number: 10815473
    Abstract: The present invention provides various combinations of genetic modifications to a transformed host cell that provide increase conversion of carbon to a chemical product. The present invention also provides methods of fermentation and methods of making various chemical products.
    Type: Grant
    Filed: December 11, 2018
    Date of Patent: October 27, 2020
    Assignee: CARGILL, INCORPORATED
    Inventors: Hans Liao, Christopher Patrick Mercogliano, Travis Robert Wolter, Michael Tai Man Louie, Wendy Kathleen Ribble, Tanya Lipscomb, Eileen Colie Spindler, Michael D. Lynch
  • Publication number: 20200308613
    Abstract: A recombinant cell for producing a fatty acid ester. The recombinant cell is genetically engineered to produce a reduction in free fatty acids compared to a cell that has not been similarly genetically engineered. Methods for producing fatty acid esters while decreasing free fatty acid production are also described.
    Type: Application
    Filed: April 1, 2020
    Publication date: October 1, 2020
    Applicant: CARGILL, INCORPORATED
    Inventors: Michael Tai Man LOUIE, Ana NEGRETE-RAYMOND, Travis Robert WOLTER
  • Publication number: 20190360010
    Abstract: Genes encoding mutant 3-ketoacyl-CoA synthases are introduced into host cells. Certain of the mutants enhance the production of shorter-chain fatty acids and derivatives by the cell than do the wild-type (unmutated) enzymes. In other cases, the chain length is not significantly affected, but productivity is enhanced. In specific cases, both a shift toward lower chain length and higher productivity is seen. Cells producing the mutant 3-ketoacyl-CoA synthases are especially suitable for producing C6-C10 fatty acids and derivatives.
    Type: Application
    Filed: February 1, 2018
    Publication date: November 28, 2019
    Applicant: GARGILL, INCORPORATED
    Inventors: Hans H. LIAO, Catherine Bradshaw POOR, Travis Robert WOLTER, Michael Tai Man LOUIE, Erin Kathleen MARASCO, Ana NEGRETE-RAYMOND
  • Publication number: 20190127725
    Abstract: The present invention provides various combinations of genetic modifications to a transformed host cell that provide increase conversion of carbon to a chemical product. The present invention also provides methods of fermentation and methods of making various chemical products.
    Type: Application
    Filed: December 11, 2018
    Publication date: May 2, 2019
    Inventors: Hans Liao, Christopher Patrick Mercogliano, Travis Robert Wolter, Michael Tai Man Louie, Wendy Kathleen Ribble, Tanya Lipscomb, Eileen Colie Spindler, Michael D. Lynch
  • Patent number: 10155937
    Abstract: The present invention provides various combinations of genetic modifications to a transformed host cell that provide increase conversion of carbon to a chemical product. The present invention also provides methods of fermentation and methods of making various chemical products.
    Type: Grant
    Filed: September 19, 2016
    Date of Patent: December 18, 2018
    Assignee: CARGILL, INCORPORATED
    Inventors: Hans Liao, Christopher Patrick Mercogliano, Travis Robert Wolter, Michael Tai Man Louie, Wendy Kathleen Ribble, Tanya E. W. Lipscomb, Eileen Colie Spindler, Michael D. Lynch
  • Patent number: 10047383
    Abstract: The present invention provides various combinations of genetic modifications to a transformed host cell that provide increase conversion of carbon to a chemical product. The present invention also provides methods of fermentation and methods of making various chemical products.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: August 14, 2018
    Assignee: CARGILL, INCORPORATED
    Inventors: Hans Liao, Christopher Patrick Mercogliano, Travis Robert Wolter, Michael Tai Man Louie, Wendy Kathleen Ribble, Tanya Lipscomb, Eileen Colie Spindler, Michael Lynch
  • Patent number: 9821713
    Abstract: The invention uses the backlight of a display monitor such as LCD monitor or OLED monitor as the lighting to replace dome light lamp in a vehicle. The in-vehicle lighting device has an input circuit for inputting commands to generate the dome light, a control circuit for receiving the commands and outputting an equivalent panel signal, and a display monitor for receiving the equivalent panel signal and emitting the dome light based on the equivalent panel signal.
    Type: Grant
    Filed: October 7, 2013
    Date of Patent: November 21, 2017
    Assignee: JET OPTOELECTRONICS CO., LTD.
    Inventors: Chien-Hung Tai, Michael Tai-Hao Wen
  • Patent number: 9652900
    Abstract: A vehicle monitoring system, comprises: at least a sensor; a head unit; at least a smart unit; wherein the sensor is capable of detecting vehicle status, generating a corresponding signal and then sending the generated signal to the head unit; the head unit is capable of receiving and analyzing the generated signal, and generating an analysis result, and they informing whether the vehicle status is abnormal by outputting a warning in the vehicle or sending the analysis result to the smart unit; the smart unit is authorized by the head unit and capable of displaying the analysis result.
    Type: Grant
    Filed: March 27, 2014
    Date of Patent: May 16, 2017
    Assignee: Jet Optoelectronics Co., Ltd.
    Inventor: Michael Tai-Hao Wen
  • Publication number: 20170101638
    Abstract: The present invention provides various combinations of genetic modifications to a. transformed host cell that provide increase conversion of carbon to a chemical product. The present invention also provides methods of fermentation and methods of making various chemical products.
    Type: Application
    Filed: September 19, 2016
    Publication date: April 13, 2017
    Inventors: Hans Liao, Christopher Patrick Mercogliano, Travis Robert Wolter, Michael Tai Man Louie, Wendy Kathleen Ribble, Tanya E. W. Lipscomb, Eileen Colie Spindler, Michael D. Lynch
  • Publication number: 20170048577
    Abstract: The disclosure is related to a remote control method related to an HDMI-CEC specification, and a system thereof. In the remote control method, a remote control program is initiated in a mobile device. The remote control program is activated to search for devices near the mobile device especially the devices that are supporting the specification of HDMI-CEC. The search result shows the options provided for user to select one device to be controlled. Under the HDMI-CEC-enabled system, one starting device and one or more peripheral devices are included in one scenario; and every device connected to a wireless signal transceiver being the controlled device is another scenario. The remote control program initiates a control interface corresponding to the selected device. Any control instruction generated is transmitted to the device to be controlled through the wireless signal transceiver.
    Type: Application
    Filed: November 25, 2015
    Publication date: February 16, 2017
    Inventors: JUH-FUH CHIOU, MICHAEL TAI-HAO WEN
  • Patent number: 9447438
    Abstract: The present invention provides various combinations of genetic modifications to a transformed host cell that provide increase conversion of carbon to a chemical product. The present invention also provides methods of fermentation and methods of making various chemical products.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: September 20, 2016
    Assignee: Cargill, Incorporated
    Inventors: Hans Liao, Christopher Patrick Mercogliano, Travis Robert Wolter, Michael Tai Man Louie, Wendy Kathleen Ribble, Tanya Lipscomb, Eileen Colie Spindler, Michael D Lynch
  • Patent number: D760183
    Type: Grant
    Filed: April 24, 2015
    Date of Patent: June 28, 2016
    Assignee: JET OPTOELECTRONICS CO., LTD.
    Inventors: Hsin-Ying Lu, Michael Tai-Hao Wen
  • Patent number: D765050
    Type: Grant
    Filed: April 24, 2015
    Date of Patent: August 30, 2016
    Assignee: JET OPTOELECTRONICS CO., LTD.
    Inventor: Michael Tai-Hao Wen
  • Patent number: D789325
    Type: Grant
    Filed: April 26, 2016
    Date of Patent: June 13, 2017
    Assignee: JET OPTOELECTRONICS CO., LTD.
    Inventors: Terry Hsiao-Yang Huang, Michael Tai-Hao Wen