Abstract: Aspects of this invention, inter alia, relate to novel systems for targeting, editing or manipulating DNA in a cell, using novel synthetic RNA-guided nucleases (sRGNs). The sRGNs are derived from wildtype or parental small type II CRISPR Cas9 endonucleases.

Abstract: A fluid flow system for a rotatable shaft assembly includes a first fluid flow device installed in a rotatable shaft, and a second fluid flow device installed in the rotatable shaft, spaced axially apart from the first fluid flow device. The first fluid flow device includes a wall portion having a radial dimension that retains oil in the rotatable shaft. The second fluid flow device includes a wall portion having a radial dimension that facilitates discharge of oil from the radial shaft. The first and second fluid flow devices each include a plurality of baffles on the respective wall portions thereof. The plurality of baffles drive the flow of fluid in an axial direction, from the first fluid flow device toward the second fluid flow device, as the first and second fluid flow devices rotate together with the rotatable shaft.

Abstract: A powertrain utilizing an active core motor with coaxially aligned planetary-differential-planetary gear assemblies is provided.

Abstract: A torque limiting clutch assembly is provided that is mounted between the motor housing and the ring gear of a planetary gear assembly. During normal operation, the clutch assembly prevents rotation of the ring gear relative to the motor housing. In the event of a severe loading condition, the clutch assembly slips, thereby preventing excessive torque from being applied to the drive train and potentially damaging one or more drive train components.

Abstract: A torque limiting clutch assembly is provided that is mounted between the motor housing and the ring gear of a planetary gear assembly. During normal operation, the clutch assembly prevents rotation of the ring gear relative to the motor housing. In the event of a severe loading condition, the clutch assembly slips, thereby preventing excessive torque from being applied to the drive train and potentially damaging one or more drive train components.

Abstract: A powertrain utilizing an active core motor with coaxially aligned planetary-differential-planetary gear assemblies is provided.

Abstract: A dual speed gearbox is provided that utilizes hydraulically actuated one way clutches and a planetary gear assembly to shift between a direct drive configuration and an overdrive configuration.

Abstract: The present invention relates to a method for the production calcium sulfoaluminate (belite, ferrite, ternesite) clinker using fluxes/mineralizers comprising the following steps —providing a raw meal comprising at least sources of CaO, AI2O3, SO3 —sintering the raw meal in a kiln at 1100 to 1350° C. to provide a clinker, —cooling the clinker, wherein at least one compound containing copper and a glass powder or a glass powder are added prior to sintering. The invention further relates to the clinker obtained, as well as to calcium sulfoaluminate based cements and binders produced from the clinker.