Abstract: One example method includes receiving a digital image of a needle core prostate biopsy, displaying, using a display device, a magnified portion of the digital image, obtaining, from a deep learning model, Gleason scores corresponding to patches of the magnified portion of the digital image, and displaying, using the display device, a superimposed overlay on the magnified portion of the digital image based on the Gleason scores and corresponding confidence values of the Gleason scores, the superimposed overlay comprising one or more outlines corresponding one or more Gleason scores associated with the magnified portion of the digital image and comprising image patches having colors based on a Gleason score of the Gleason scores corresponding to an underlying portion of the magnified portion of the digital image and a confidence value of the corresponding Gleason score.

Abstract: A method includes receiving a request indication indicating a GUI interaction by a user on a user device, and in response, providing to the device a response configured to cause the device to display, within a GUI, a structured prompt including a plurality of user input fields, each user input field representing a corresponding training sample and including a first corresponding text input field for capturing input text to be provided to an ML model, and a second corresponding text input field for capturing ground-truth output text. The method also includes receiving, from the device, the training samples, and, in response, adjusting the ML model using the training samples. The method further includes receiving, from the device, test input text, generating, using the adjusted ML model, test output text based on the test input text, and providing, to the user device, the test output text for display within the GUI.

Abstract: One example method includes receiving a digital image of a needle core prostate biopsy, displaying, using a display device, a magnified portion of the digital image, obtaining, from a deep learning model, Gleason scores corresponding to patches of the magnified portion of the digital image, and displaying, using the display device, a superimposed overlay on the magnified portion of the digital image based on the Gleason scores and corresponding confidence values of the Gleason scores, the superimposed overlay comprising one or more outlines corresponding one or more Gleason scores associated with the magnified portion of the digital image and comprising image patches having colors based on a Gleason score of the Gleason scores corresponding to an underlying portion of the magnified portion of the digital image and a confidence value of the corresponding Gleason score.

Abstract: Systems and methods are disclosed for managing the operation of a plant, such as a chemical plant or a petrochemical plant or a refinery, and more particularly for enhancing system performance of a catalyzed reaction system by, among other features, detecting catalyst deactivation and cycle length. Plants may include those that provide hydrocarbon cracking or other process units. A plant may include a reactor, a heater, a catalyst bed, a separator, and other equipment. The equipment may use catalyst to treat feed products to remove compounds and produce different products. Catalysts used in the various reactors in these processes become deactivated over time. Systems and methods are disclosed for extending catalyst life and thereby improving efficiency of the plant.

Abstract: Systems and methods are disclosed for managing the operation of a plant, such as a chemical plant or a petrochemical plant or a refinery, and more particularly for enhancing system performance of a catalyzed reaction system by, among other features, detecting catalyst deactivation and cycle length. Plants may include those that provide hydrocarbon cracking or other process units. A plant may include a reactor, a heater, a catalyst bed, a separator, and other equipment. The equipment may use catalyst to treat feed products to remove compounds and produce different products. Catalysts used in the various reactors in these processes become deactivated over time. Systems and methods are disclosed for extending catalyst life and thereby improving efficiency of the plant.

Abstract: Described herein are devices and techniques for no-hole-prep installation of miniaturized suture anchors into bone.

Abstract: A fuse system for use with a disposable component of a device may include a disposable component having at least a first lockout circuit and a second lockout circuit. The first lockout circuit may include a first fuse link, and the second lockout circuit may include a second fuse link. The fuse system may include a computing device in communication with the first lockout circuit and the second lockout circuit, and a computer-readable storage medium in communication with the computing device. The computer-readable storage medium may include one or more programming instructions for deactivating the first fuse link at a first time, and deactivating the second fuse link at a second time.

Abstract: A fuse system for a hyperthermia apparatus may include a disposable reservoir cartridge configured to be used with a hyperthermia apparatus. The disposable reservoir cartridge may include at least a first lockout circuit and a second lockout circuit. The first lockout circuit may include a first fuse link, and the second lockout circuit may include a second fuse link. The fuse system may include a computing device in communication with the first lockout circuit and the second lockout circuit, and a computer-readable storage medium in communication with the computing device. The computer-readable storage medium may include one or more programming instructions for deactivating the first fuse link at a first time, and deactivating the second fuse link at a second time.

Abstract: A fabric softening composition comprising from 1 to 80% by weight of ester-linked quaternary ammonium fabric softening material comprising a quaternised mixture of mono- di- and tri-ester of alkanolamine in which the tri-ester content of said mixture is from 25 to 50% by weight of said mixture, wherein: (i) when the tri-ester content is from 25 to 30% by weight of said mixture the free amine content of the composition is less than 0.5% by weight on the weight of said mixture, (ii) when the tri-ester content is more than 30% by weight of said mixture the free amine content of the composition is less than 6% by weight based on the weight of said mixture, the composition containing less than 1% by weight of free fatty acid based on said mixture.

Abstract: The present disclosure relates to a surgical device including an anchor body defining a cavity and an opening to the cavity, and a flexible member extending through the opening and having a sliding knot disposed within the cavity. The anchor body includes at least two longitudinally extending slots on an outer surface of the anchor body. The disclosure also relates to a surgical device including a handle, an outer shaft including a flanged end portion and a longitudinally extending slot, and an inner shaft received within the outer shaft. The inner shaft includes a first end and a second end, wherein the first end is coupled to the handle. The outer shaft is movable between a first position and a second position with respect to the handle. Methods of repairing a soft tissue are also disclosed.

Abstract: Techniques for archiving audio information communicated between members of a group using an audio communication system such as a point-to-multipoint audio communication system. The archived audio information can then be retrieved by members of the group or by any other user at any time subsequent to the live transmission of the audio information. Audio information communications between communication devices used by members of a group are monitored and recorded. The recorded audio information is then analyzed to identify one or more conversation portions in the audio information. Audio information corresponding to the conversation portions is then archived. The archived information is then available for retrieval.

Abstract: This disclosure relates to fault tolerant instantiations of a cardiac therapy delivery device such as an implantable cardiac stimulator (e.g., an implantable pulse generator, IPG, and/or an implantable cardioverter-defibrillator, ICD) coupled to an implantable physiologic sensor (IPS). According to the disclosure delivery of cardiac pacing and/or cardioversion-defibrillator therapy delivery can cause errors in output signals from an IPS. Resolution of such errors involves selectively energizing (or disconnecting the output signal from) the IPS during pacing and/or defibrillation therapy delivery. Programmable signal “blanking” in lieu of or in addition to the foregoing also improves the integrity of the output signal (i.e., continuously energize the IPS and ignore parts of the output signal). An ICD having a transient weakness in an insulated conductor used for the IPS signal can likewise have the IPS de-energized and/or blank the IPS output signal during high voltage therapy delivery.

Abstract: The invention involves monitoring on a continuous or non-continuous basis the electrical drain of a chronically implanted physiologic sensor. One of a pair of conductors is monitored for excessive current drain. For example, if an inner sensor-signal bearing conductor (of a co-axial pair) contacts conductive body fluid or tissue (e.g., due to insulation breach), a measurement of current quickly reveals the fault. Accordingly, if an increase in or a supra-threshold electrical current drain is detected the sensor power supply is disengaged. In one form, dedicated physiologic sensor to electrical circuitry disposed within the AIMD. In another form, the AIMD is adapted to sense a physiologic parameter and deliver therapy (e.g., via one or more electrodes). A manual or automatic reset can be implemented in the event that the failure mode resolves itself. The reset can include criteria such as three consecutive sub-threshold current measurements before normal operation resumes.

Abstract: Certain embodiments of the present invention provide an improved suturing system and method of use. Certain embodiments include a suturing device with a base and a hook end capable of being maneuvered to a certain position with respect to the base. The hook end may be maneuvered to a position, such as a straight position or a desired angle. The hook end may be locked at the position. The hook end may also be detachable from the base, for example. The hook end may be selected from a plurality of hook attachments having different characteristics, for example. In an embodiment, the suturing device also includes a control for maneuvering the hook end with respect to the base. In an embodiment, the suturing device further includes a locking mechanism for locking the hook end to the base.

Abstract: Techniques for archiving audio information communicated between members of a group using an audio communication system such as a point-to-multipoint audio communication system. The archived audio information can then be retrieved by members of the group or by any other user at any time subsequent to the live transmission of the audio information. Audio information communications between communication devices used by members of a group are monitored and recorded. The recorded audio information is then analyzed to identify one or more conversation portions in the audio information. Audio information corresponding to the conversation portions is then archived. The archived information is then available for retrieval.