Abstract: The present disclosure relates to a novel class of bifunctional molecules that are useful in a targeted or selective degradation of a protein.

Abstract: Fairnetting and distribution of electronic trades is described, where, a computing device includes a reception module, a trade organization module, and a trade netting module. The trade organization module organizes one or more trades, received by the reception module, by currency pairs. The trade netting module generates, at a first point in time, a netting plan designed to offset a trade against at least one other trade, and estimates, for the netting plan, a first value that is proportional to an expected savings based on real-time market data and associated with executing the trades according to the netting plan versus executing the trades without the netting plan, where the first value is not exceeded by a cost of trading proportional to a change in market value of the trades between the first point in time and a time that a first trade included in the trades is executed.

Abstract: Methods and apparatuses are provided for facilitating fairnetting and the distribution of currency trades. In one example, the method may include: (i) estimating non-provided trade information for each trade type of aggregated sets of trades of a plurality of trades using a market mid-rate; (ii) determining a netted amount and a market amount to transact based on received trade information and the estimated non-provided trade information; (iii) executing one or more trades for the market amount at a market rate; and (iv) distributing the market amount and the netted amount proportionally amongst the plurality of trades.