Abstract: An auger system may include a powerhead, a bit, and an anchoring device. A collar on the bit may be attachable to a rotatable output shaft of the powerhead with a coupler that is positionable around the collar. The collar may include a passageway that does not intersect the rotation axis of the output shaft. The coupler may have a pin that is positionable to extend into the passageway to engage part of the output shaft to resist removal of the bit from the output shaft. The anchoring device may have a tube that is positionable to rest in slots between two lobes extending from a frame of the powerhead. A pintle assembly may pass through the tube and the lobes to rotatably mount the anchoring device on the frame. A toggle and a spring in the pintle assembly may keep the pintle assembly in position.

Abstract: Provided herein are methods for identifying a subject as a responder or non-responder to immune checkpoint blockade by detecting a B cell signature. Further provided herein are methods for treating cancer by administering immune checkpoint blockade therapy to a subject identified to have a B cell signature.