Abstract: Exercise apparatus for exercising the upper body simultaneously with lower body exercise, comprising a lower body exercise machine and at least one upper body exercise module positioned for use in conjunction with the lower body exercise machine. The upper body exercise module comprises an elongated connector having first and second ends; a user engagement connected to the elongated connector first end for engaging or being engaged by a body appendage of a user; and a resistance mechanism for resisting a force applied to the first end of the elongated connector. Each upper body exercise module is adapted to provide resistance to a full, natural arm swing of at least one arm of the user. Various types of lower body exercise machines, resistance devices, user engagements, relationships between the upper body exercise module and the lower body exercise machine, and exercise methods using the apparatus are disclosed.

Abstract: A diagnostic method is disclosed which utilizes short C-terminal fragments of Borrelia burgdorferi sensu lato derived protein OspC. The 4 amino-terminal acids Pro-Lys-Pro (SEQ ID NO: 22) are shown to be essential in immune reactivity between sera from patients suffering from early borreliosis and various OspC derivatives and it is shown that in order to be effective as a diagnostic agent, 5 consecutive amino acid residues long homologue of a fragment identical to the 10 C-terminal amino acids of OspC (SEQ DI NO: 1). Also disclosed are vaccines utilizing the short peptides as well as methods for their preparation.

Abstract: Novel vaccines for use in the prevention and treatment of H. somnus infections are disclosed. The vaccines contain epitopes from LppA, LppB, LppC or combinations thereof. Also disclosed are the nucleotide sequences encoding these lipoproteins, vectors including these sequences, and host cells transformed with these vectors.