Patents by Inventor Michael Tobyn
Michael Tobyn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20120321717Abstract: The present invention relates to enhancing the dosing efficiency of pharmaceutical dry powder formulations administered by pulmonary inhalation. In particular, the present invention relates to the provision of dry powder inhalers and dry powder compositions which reproducibly achieve a much higher delivered dose of the pharmaceutically active agent than currently achieved.Type: ApplicationFiled: May 4, 2012Publication date: December 20, 2012Applicant: VECTURA LTD.Inventors: John Nicholas Staniforth, David Morton, Michael Tobyn, Stephen Eason, Quentin Harmer, David Granderton
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Patent number: 7927034Abstract: An applicator for applying a spreadable composition to the skin or other exterior region of a human or animal body, comprising receiving means for receiving and carrying a unit or measured dose of the composition and a grip for enabling a user to grip and manipulate the applicator, wherein the grip and receiving means are arranged such that a user gripping the applicator by the grip is protected from inadvertent contact with a composition, a unit or measured dose of which is carried by the receiving means.Type: GrantFiled: May 6, 2003Date of Patent: April 19, 2011Assignee: Pharmakodex LimitedInventors: John Staniforth, Michael Tobyn, Sharon Ann Mills, Christopher John Althorpe
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Publication number: 20100297030Abstract: A composition, device, and method for treating sexual dysfunction via inhalation is provided which comprises inhaling a dose of apomorphine or pharmaceutically acceptable salt(s) or ester(s) thereof.Type: ApplicationFiled: December 9, 2009Publication date: November 25, 2010Applicant: Vectura Drug DeliveryInventors: John Nicholas Staniforth, David Alexander Vodden Morton, Michael Tobyn, Stephen Eason, Quentin Harmer, David Ganderton
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Publication number: 20100018523Abstract: A composition, device, and method for treating sexual dysfunction via inhalation is provided which comprises inhaling a dose of a powder composition, the powder composition comprising apomorphine or pharmaceutically acceptable salts thereof. Preferably, the powder composition further includes a carrier material, the carrier material has an average particle size of from about 40 to about 70 microns, and at least 90 percent of said apomorphine has a particle size of 5 microns or less.Type: ApplicationFiled: July 6, 2009Publication date: January 28, 2010Inventors: John Nicolas Staniforth, David Alexander Vodden Morton, Michael Tobyn, Stephen Eason, Quentin Harmer, David Ganderton
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Publication number: 20090011031Abstract: Disclosed is a system for delivery of a drug comprising a multiple unit dosing device comprising a chousing and an actuator, said device containing multiple doses of multiparticulates comprising drug particles, said device upon actuation delivering a unit dose of said multiparticulates, said drug particles having a mean diameter of greater than 10 ?m to about 1 mm such that an effective dose of said drug cannot be delivered into the lower lung of a human patient. Also disclosed are novel methods, devices and dosage forms for delivering a drug.Type: ApplicationFiled: June 17, 2008Publication date: January 8, 2009Applicant: PharmaKodex Ltd.Inventors: John Staniforth, Michael Tobyn
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Patent number: 7089934Abstract: Disclosed is a system for delivery of a drug comprising a multiple unit dosing device comprising a housing and an actuator, said device containing multiple doses of multiparticulates comprising drug particles, said device upon actuation delivering a unit dose of said multiparticulates, said drug particles having a mean diameter of greater than 10 ?m to about 1 mm such that an effective dose of said drug cannot be delivered into the lower lung of a human patient. Also disclosed are novel methods, devices and dosage forms for delivering a drug.Type: GrantFiled: February 26, 2001Date of Patent: August 15, 2006Assignee: Vectura LimitedInventors: John Staniforth, Michael Tobyn
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Publication number: 20060178394Abstract: The present invention relates to inhalable formulations of apomorphine or its pharmaceutically acceptable salts or esters for use in treating sexual dysfunction. The present invention also relates to methods for preparing the apomorphine formulations as well as to methods for treatment of sexual dysfunction using said formulations and inhalers including said formulations. The present invention further relates to the use of apomorphine in the manufacture of a medicament for treating sexual dysfunction.Type: ApplicationFiled: April 14, 2004Publication date: August 10, 2006Inventors: John Staniforth, David Morton, Michael Tobyn, Stephen Eason, Quentin Harmer, David Ganderton
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Publication number: 20060147389Abstract: The present invention relates to enhancing the dosing efficiency of pharmaceutical dry powder formulations administered by pulmonary inhalation. In particular, the present invention relates to the provision of dry powder inhalers and dry powder compositions which reproducibly achieve a much higher delivered dose of the pharmaceutically active agent than currently achieved.Type: ApplicationFiled: April 14, 2004Publication date: July 6, 2006Applicant: Vectura Ltd.Inventors: John Staniforth, David Morton, Michael Tobyn, Stephen Eason, Quentin Harmer, David Ganderton
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Publication number: 20060127480Abstract: A pharmaceutical excipient comprising a solid, reticulated matrix, wherein the matrix comprises an aggregation of inorganic particles in association with an organic polymeric material, defines a plurality of pores with a mean width in the range of about 0.01-500 m, and has a specific surface area of at least about 1 m2/g is described, as are products comprising such excipients, methods of making them and use thereof.Type: ApplicationFiled: October 10, 2003Publication date: June 15, 2006Inventors: Michael Tobyn, John Staniforth, Cheryl Clinch, Matthew Hearn, Dominic Walsh, Simon Hall
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Publication number: 20050261163Abstract: A pharmaceutical product comprising at least one therapeutic agent, whereby a unit dose of said therapeutic agent as provided by said pharmaceutical product can be administered to a patient during the passage of said therapeutic agent through the gastrointestinal tract of the patient, wherein said therapeutic agent is characterised as having an aqueous solubility of not greater than about 1 in 30 to 1 in 100, weight/volume, when measured at a temperature in the range of 15 to 25° C.Type: ApplicationFiled: April 9, 2002Publication date: November 24, 2005Inventors: Michael Tobyn, John Staniforth, Cheryl Clinch, Matthew Hearn
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Publication number: 20050205083Abstract: A multiple dose delivery device for delivering a medicament into an oral cavity of a patient is provided. The device includes a sachet pack including a plurality of unit doses of a medicament enclosed between a first strip and a second strip. The device further includes a sachet advance mechanism and a mouthpiece. Upon actuation by a user, the sachet advance mechanism, which is engaged with the sachet pack, separates the first strip from the second strip to release one of the plurality of the unit doses from the sachet pack. The mouthpiece includes an opening, and each released unit dose passes through the opening.Type: ApplicationFiled: April 27, 2005Publication date: September 22, 2005Applicant: Vectura LimitedInventors: John Staniforth, Michael Tobyn, Nicholas Bowman, Matthew Wright, Gary Howard, David Brook Simpson
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Patent number: 6941948Abstract: A multiple dose delivery device for delivering a medicament into an oral cavity of a patient is provided. The device includes a sachet pack including a plurality of unit doses of a medicament enclosed between a first strip and a second strip. The device further includes a sachet advance mechanism and a mouthpiece. Upon actuation by a user, the sachet advance mechanism, which is engaged with the sachet pack, separates the first strip from the second strip to release one of the plurality of the unit doses from the sachet pack. The mouthpiece includes an opening, and each released unit dose passes through the opening.Type: GrantFiled: March 7, 2003Date of Patent: September 13, 2005Assignee: Vectura Drug DeliveryInventors: John Nicholas Staniforth, Michael Tobyn, Nicolas John Bowman, Matthew Wright, Gary Stephen Howard, David Bradley Brook Simpson
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Publication number: 20050158394Abstract: Disclosed is a system for delivery of a drug comprising a multiple unit dosing device comprising a housing and an actuator, said device containing multiple doses of multiparticulates comprising drug particles, said device upon actuation delivering a unit dose of said multiparticulates, said drug particles having a mean diameter of greater than 10 ?m to about 1 mm such that an effective dose of said drug cannot be delivered into the lower lung of a human patient. Also disclosed are novel methods, devices and dosage forms for delivering a drug.Type: ApplicationFiled: January 6, 2005Publication date: July 21, 2005Applicant: Vectura LimitedInventors: John Staniforth, Michael Tobyn
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Publication number: 20050054991Abstract: Disclosed is a dosing device for topically administering a pharmaceutical formulation to a skin of a mammal, the device comprising a housing capable of holding at least one unit dose of a pharmaceutical formulation comprising a drug and a carrier; an applicator adapted for topically administering a unit dose of the pharmaceutical formulation directly onto the skin; and an actuator, wherein upon actuation, the device is capable of metering a unit dose of the pharmaceutical formulation external to the device, from the housing to the applicator; and methods thereof.Type: ApplicationFiled: August 28, 2002Publication date: March 10, 2005Inventors: Michael Tobyn, John Staniforth, Sharon Mills, Graeme Paterson, Christopher Althorpe
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Publication number: 20050013862Abstract: In certain embodiments the invention is directed to a drug formulation for gastrointestinal deposition comprising a non-compressed free flowing plurality of particles comprising a core comprising a drug and a pharmaceutically acceptable excipient, said core overcoated with a functional coating, said drug particles having a mean diameter of greater than 10 ?m to about 1 mm.Type: ApplicationFiled: September 5, 2002Publication date: January 20, 2005Applicant: Vectura LimitedInventors: Michael Tobyn, John Staniforth, David Bradley Simpson
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Publication number: 20040204439Abstract: A composition, device, and method for treating sexual dysfunction via inhalation is provided which comprises inhaling a dose of a powder composition, the powder composition comprising apomorphine or pharmaceutically acceptable salts thereof. Preferably, the powder composition further includes a carrier material, the carrier material has an average particle size of from about 40 to about 70 microns, and at least 90 percent of said apomorphine has a particle size of 5 microns or less.Type: ApplicationFiled: April 14, 2003Publication date: October 14, 2004Inventors: John Nicholas Staniforth, David Alexander Vodden Morton, Michael Tobyn, Stephen Eason, Quentin Harmer, David Ganderton
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Publication number: 20040204440Abstract: A composition, device, and method for treating sexual dysfunction via inhalation is provided which comprises inhaling a dose of apomorphine or pharmaceutically acceptable salt(s) or ester(s) thereofType: ApplicationFiled: July 17, 2003Publication date: October 14, 2004Inventors: John Nicholas Staniforth, David Alexander Vodden Morton, Michael Tobyn, Stephen Eason, Quentin Harmer, David Ganderton
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Publication number: 20040071494Abstract: An applicator for applying a spreadable composition to the skin or other exterior region of a human or animal body, comprising receiving means for receiving and carrying a unit or measured dose of the composition and a grip for enabling a user to grip and manipulate the applicator, wherein the grip and receiving means are arranged such that a user gripping the applicator by the grip is protected from inadvertent contact with a composition, a unit or measured dose of which is carried by the receiving means.Type: ApplicationFiled: May 6, 2003Publication date: April 15, 2004Inventors: John Staniforth, Michael Tobyn, Sharon Ann Mills, Christopher John Althorpe
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Publication number: 20030172924Abstract: A multiple dose delivery device for delivering a medicament into an oral cavity of a patient is provided. The device includes a sachet pack including a plurality of unit doses of a medicament enclosed between a first strip and a second strip. The device further includes a sachet advance mechanism and a mouthpiece. Upon actuation by a user, the sachet advance mechanism, which is engaged with the sachet pack, separates the first strip from the second strip to release one of the plurality of the unit doses from the sachet pack. The mouthpiece includes an opening, and each released unit dose passes through the opening.Type: ApplicationFiled: March 7, 2003Publication date: September 18, 2003Inventors: John Nicholas Staniforth, Michael Tobyn, Nicolas John Bowman, Matthew Wright, Gary Stephen Howard, David Bradley Brook Simpson
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Publication number: 20010020147Abstract: Disclosed is a system for delivery of a drug comprising a multiple unit dosing device comprising a housing and an actuator, said device containing multiple doses of multiparticulates comprising drug particles, said device upon actuation delivering a unit dose of said multiparticulates, said drug particles having a mean diameter of greater than 10 &mgr;m to about 1 mm such that an effective dose of said drug cannot be delivered into the lower lung of a human patient. Also disclosed are novel methods, devices and dosage forms for delivering a drug.Type: ApplicationFiled: February 26, 2001Publication date: September 6, 2001Inventors: John Staniforth, Michael Tobyn