Patents by Inventor Michael Torgov

Michael Torgov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibody drug conjugates (ADC) that bind to 161P2F10B proteins
    Patent number: 9308278
    Abstract: Antibody drug conjugates (ADC's) that bind to 161P2F10B protein are described herein. 161P2F10B exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention provide a therapeutic composition for the treatment of cancer.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: April 12, 2016
    Assignee: Agensys, Inc.
    Inventors: Michael Torgov, Robert Kendall Morrison, Aya Jakobovits, Jean Gudas, Zili An
  • DLL3 MODULATORS AND METHODS OF USE
    Publication number: 20160075779
    Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
    Type: Application
    Filed: September 18, 2015
    Publication date: March 17, 2016
    Applicant: STEMCENTRX, INC.
    Inventors: Robert A. STULL, Laura SAUNDERS, Scott J. DYLLA, Orit FOORD, David LIU, Michael TORGOV, Hui SHAO
  • NOVEL ANTIBODY CONJUGATES AND USES THEREOF
    Publication number: 20160015828
    Abstract: Provided are novel antibody drug conjugates (ADCs), and methods of using such ADCs to treat proliferative disorders.
    Type: Application
    Filed: February 21, 2014
    Publication date: January 21, 2016
    Applicants: Spirogen Sàrl, Stemcentrx, Inc.
    Inventors: Michael TORGOV, Philip Wilson HOWARD
  • ANTI-DLL3 ANTIBODY DRUG CONJUGATES
    Publication number: 20150328332
    Abstract: Pharmaceutical compositions to treat proliferative disorders are provided.
    Type: Application
    Filed: July 23, 2015
    Publication date: November 19, 2015
    Applicant: STEMCENTRX, INC.
    Inventors: ROBERT A. STULL, LAURA SAUNDERS, SCOTT J. DYLLA, ORIT FOORD, DAVID LIU, MICHAEL TORGOV, HUI SHAO
  • Anti-DLL3 antibody drug conjugates
    Patent number: 9173959
    Abstract: Pharmaceutical compositions to treat proliferative disorders are provided.
    Type: Grant
    Filed: July 23, 2015
    Date of Patent: November 3, 2015
    Assignee: Stemcentrx, Inc.
    Inventors: Robert A. Stull, Laura Saunders, Scott J. Dylla, Orit Foord, David Liu, Michael Torgov, Hui Shao
  • ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 191P4D12 PROTEINS
    Publication number: 20150306245
    Abstract: Antibody drug conjugates (ADC's) that bind to 191P4D12 protein and variants thereof are described herein. 191P4D12 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention provide a therapeutic composition for the treatment of cancer.
    Type: Application
    Filed: July 13, 2015
    Publication date: October 29, 2015
    Applicants: AGENSYS, INC., SEATTLE GENETICS, INC.
    Inventors: Daulet SATPAYEV, Robert Kendall MORRISON, Karen Jane Meyrick MORRISON, Jean GUDAS, Aya JAKOBOVITS, Michael TORGOV, Zili AN
  • Anti-DLL3 antibody drug conjugates and methods of use
    Patent number: 9155803
    Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat tumors having neuroendocrine features are provided.
    Type: Grant
    Filed: June 8, 2015
    Date of Patent: October 13, 2015
    Assignee: Stemcentrx, Inc.
    Inventors: Robert A. Stull, Laura Saunders, Scott J. Dylla, Orit Foord, David Liu, Michael Torgov, Hui Shao
  • ANTI-DLL3 ANTIBODY DRUG CONJUGATES AND METHODS OF USE
    Publication number: 20150265724
    Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat tumors having neuroendocrine features are provided.
    Type: Application
    Filed: June 8, 2015
    Publication date: September 24, 2015
    Applicant: STEMCENTRX, INC.
    Inventors: Robert A. Stull, Laura SAUNDERS, Scott J. DYLLA, Orit FOORD, David LIU, Michael TORGOV, Hui SHAO
  • Anti-DLL3 antibody drug conjugates and methods of use
    Patent number: 9133271
    Abstract: Provide are novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat recurrent tumors and to reduce or inhibit tumor recurrence in a subject.
    Type: Grant
    Filed: June 17, 2015
    Date of Patent: September 15, 2015
    Assignee: Stemcentrx, Inc.
    Inventors: Robert A. Stull, Laura Saunders, Scott J. Dylla, Orit Foord, David Liu, Michael Torgov, Hui Shao
  • Anti-DLL3 antibody drug conjugates for treating cancer
    Patent number: 9107961
    Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
    Type: Grant
    Filed: August 22, 2014
    Date of Patent: August 18, 2015
    Assignee: Stemcentrx, Inc.
    Inventors: Robert A. Stull, Laura Saunders, Scott J. Dylla, Orit Foord, David Liu, Michael Torgov, Hui Shao
  • Anti-DLL3 antibodies
    Patent number: 9089615
    Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
    Type: Grant
    Filed: August 22, 2014
    Date of Patent: July 28, 2015
    Assignee: Stemcentrx, Inc.
    Inventors: Robert A. Stull, Laura Saunders, Scott J. Dylla, Orit Foord, David Liu, Michael Torgov, Hui Shao
  • Methods of detection, diagnosis, and monitoring using anti-DLL3 antibodies
    Patent number: 9090683
    Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
    Type: Grant
    Filed: August 22, 2014
    Date of Patent: July 28, 2015
    Assignee: Stemcentrx, Inc.
    Inventors: Robert A. Stull, Laura Saunders, Scott J. Dylla, Orit Foord, David Liu, Michael Torgov, Hui Shao
  • Anti-DLL3 antibody drug conjugates and methods of use
    Patent number: 9089616
    Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
    Type: Grant
    Filed: August 22, 2014
    Date of Patent: July 28, 2015
    Assignee: Stemcentrx, Inc.
    Inventors: Robert A Stull, Laura Saunders, Scott J. Dylla, Orit Foord, David Liu, Michael Torgov, Hui Shao
  • Anti-DLL3 antibody drug conjugates
    Patent number: 9089617
    Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
    Type: Grant
    Filed: August 22, 2014
    Date of Patent: July 28, 2015
    Assignee: Stemcentrx, Inc.
    Inventors: Robert A. Stull, Laura Saunders, Scott J. Dylla, Orit Foord, David Liu, Michael Torgov, Hui Shao
  • Antibody drug conjugates (ADC) that bind to 191P4D12 proteins
    Patent number: 9078931
    Abstract: Antibody drug conjugates (ADC's) that bind to 191P4D12 protein and variants thereof are described herein. 191P4D12 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention provide a therapeutic composition for the treatment of cancer.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: July 14, 2015
    Assignees: AGENSYS, INC., SEATTLE GENETICS, INC.
    Inventors: Daulet Satpayev, Robert Kendall Morrison, Karen Jane Meyrick Morrison, Jean Gudas, Aya Jakobovits, Michael Torgov, Zili An
  • Anti-DLL3 antibody drug conjugates and methods of use
    Patent number: 9011854
    Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
    Type: Grant
    Filed: August 22, 2014
    Date of Patent: April 21, 2015
    Assignee: Stemcentrx, Inc.
    Inventors: Robert A Stull, Laura Saunders, Scott J. Dylla, Orit Foord, David Liu, Michael Torgov, Hui Shao
  • Nucleic acid encoding DLL3 antibodies
    Patent number: 8986972
    Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
    Type: Grant
    Filed: August 22, 2014
    Date of Patent: March 24, 2015
    Assignee: Stem CentRx, Inc.
    Inventors: Robert A. Stull, Laura Saunders, Scott J. Dylla, Orit Foord, David Liu, Michael Torgov, Hui Shao
  • Antibodies Directed to GPNMB and Uses Thereof
    Publication number: 20150044212
    Abstract: The present invention provides fully human monoclonal antibodies that specifically bind to GPNMB, and uses thereof. Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDRs) are provided. The present invention also provides immunoconjugates comprising anti-GPNMB antibodies and methods of using such immunoconjugates. The present invention further provides bi-specific antibodies comprising an anti-GPNMB antibody component and an anti-CD3 component, and methods of using such bispecific antibodies.
    Type: Application
    Filed: August 7, 2014
    Publication date: February 12, 2015
    Inventors: Feng Xiao, Xiao-Chi Jia, Meina Liang, Orit Foord, Scott Klakamp, Kam Fai Tse, Vincent A. Pollack, Luca Rastelli, John Herrmann, Henri Lichenstein, Michael E. Jeffers, William J. LaRochelle, Gulshan Ara, Peter Mezes, Andrei Chapoval, Cyrus Karkaria, Michael Torgov, Juan Davagnino
  • ANTI SEZ6 ANTIBODIES AND METHODS OF USE
    Publication number: 20150018531
    Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
    Type: Application
    Filed: February 22, 2013
    Publication date: January 15, 2015
    Applicant: STEM CENTRX, INC.
    Inventors: Laura Saunders, Scott J. Dylla, Orit Foord, Robert A. Stull, Michael Torgov, Hui Shao, David Liu
  • DLL3 MODULATORS AND METHODS OF USE
    Publication number: 20140370037
    Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
    Type: Application
    Filed: August 22, 2014
    Publication date: December 18, 2014
    Applicant: STEM CENTRX, INC.
    Inventors: ROBERT A. STULL, LAURA SAUNDERS, SCOTT J. DYLLA, ORIT FOORD, DAVID LIU, MICHAEL TORGOV, HUI SHAO