Abstract: This disclosure describes techniques for maintaining and using a warehouse of data about potential or actual cyberattack threats for an industry. In one example, this disclosure describes a method that includes outputting, by a computing system operated by a first entity and to a data warehouse, information about activity within a first network operated by the first entity; receiving, by the computing system and from the data warehouse, information about attributes of a peer attack directed to a second network operated by a second entity, wherein the first entity and the second entity may be marketplace competitors; applying, by the computing system, a model to identify a network asset included within the first network that is vulnerable to an attack having the attributes of the peer attack; and outputting, by the computing system and to the network asset, a control signal to modify the operation of the network asset.

Abstract: The present invention concerns markers of multiple sclerosis, their use, and treatment with IL-17 antagonists, including IL-17 antibodies, of subjects with increased levels of such markers.

Abstract: The present invention concerns markers of multiple sclerosis, their use, and treatment with IL-17 antagonists, including IL-17 antibodies, of subjects with increased levels of such markers.

Abstract: Systems and methods for protecting a loudspeaker from excessive excursion include an audio source, an adaptive excursion protection filter, an audio clipper, an inverse excursion protection filter, an amplifier and a loudspeaker. The system performs operations including receiving an audio signal, applying an excursion protection filter, the excursion protection filter adapting in real-time to one or more speaker conditions, clipping the audio signal, applying an inverse excursion protection filter, and amplifying, using an amplification circuit, the audio signal for output to the speaker.

Abstract: The present invention concerns markers of multiple sclerosis, their use, and treatment with IL-17 antagonists, including IL-17 antibodies, of subjects with increased levels of such markers.

Abstract: Systems and methods for protecting a loudspeaker from excessive excursion include an audio source, an adaptive excursion protection filter, an audio clipper, an inverse excursion protection filter, an amplifier and a loudspeaker. The system performs operations including receiving an audio signal, applying an excursion protection filter, the excursion protection filter adapting in real-time to one or more speaker conditions, clipping the audio signal, applying an inverse excursion protection filter, and amplifying, using an amplification circuit, the audio signal for output to the speaker.

Abstract: The present invention concerns markers of multiple sclerosis, their use, and treatment with IL-17 antagonists, including IL-17 antibodies, of subjects with increased levels of such markers.

Abstract: Systems and methods for protecting a loudspeaker from excessive excursion include an audio source, an adaptive excursion protection filter, an audio clipper, an inverse excursion protection filter, an amplifier and a loudspeaker. The system performs operations including receiving an audio signal, applying an excursion protection filter, the excursion protection filter adapting in real-time to one or more speaker conditions, clipping the audio signal, applying an inverse excursion protection filter, and amplifying, using an amplification circuit, the audio signal for output to the speaker.

Abstract: Systems and methods for protecting a loudspeaker from excessive excursion include an audio source, an adaptive excursion protection filter, an audio clipper, an inverse excursion protection filter, an amplifier and a loudspeaker. The system performs operations including receiving an audio signal, applying an excursion protection filter, the excursion protection filter adapting in real-time to one or more speaker conditions, clipping the audio signal, applying an inverse excursion protection filter, and amplifying, using an amplification circuit, the audio signal for output to the speaker.

Abstract: Provided herein are biomarkers and therapies for the treatment of autoimmune and/or inflammatory diseases, such as lupus, and methods of using BTK inhibitors. In particular, provided are biomarkers for patient selection and prognosis in lupus, as well as methods of therapeutic treatment, articles of manufacture and methods for making them, diagnostic kits, methods of detection and methods of advertising related thereto.

Abstract: The present invention provides diagnostic and therapeutic methods and compositions for treating a patient suffering from an interleukin-1 receptor-associated kinase 4 (IRAK4)-mediated disorder or condition, such as an immune disorder (e.g., systemic lupus erythematosus (SLE)) or an inflammatory disorder (e.g., asthma). The invention provides diagnostic methods of monitoring the response of a patient having an IRAK4-mediated disorder or condition to treatment including an IRAK4 pathway inhibitor, methods of identifying a patient having an IRAK4-mediated disorder or condition who may benefit from treatment including an IRAK4 pathway inhibitor, and methods of selecting a therapy for a patient having an IRAK4-mediated disorder or condition based on the expression level of one or more IRAK4 biomarkers (e.g., one or more genes set forth in Table 1). Related therapeutic methods and compositions (e.g., diagnostic kits) are also provided.

Abstract: The present invention concerns markers of multiple sclerosis, their use, and treatment with IL-17 antagonists, including IL-17 antibodies, of subjects with increased levels of such markers.

Abstract: A stream redirecting device for a sprinkler includes a shell-shaped body having a generally semi-circular shape in plan, with opposite inlet and outlet side edges. The body extends outwardly and upwardly from a base at a lower end and then upwardly and inwardly to a distal, arcuate edge at an upper end. An inside surface of the shell-shaped body is formed with a plurality of grooves between the inlet side edge and the outlet side edge, extending in a generally radial direction with entry ends adjacent the base and exit ends at the distal, arcuate edge. The grooves are formed with circumferential exit angles that vary substantially uniformly in opposite directions from a center one of the plurality of grooves to first and last of the plurality of grooves at the opposite inlet and outlet side edges, respectively.

Abstract: Briefly, one or more embodiments of a process, system, apparatus or article to edit electronic content is provided. Electronic content may be displayed in an application. A snapshot of a portion of the electronic content may be created. An edit and/or a comment may be received that provides context for the comment. A review that includes the snapshot and edit and/or comment may be published to one or more recipients. At least one of the one or more recipients may be configured to receive the review and display the review using a different application.

Abstract: A sprinkler assembly includes a housing having an open side; a sprinkler body supported at one end of the housing and adapted to receive a nozzle. A nozzle magazine is attached to the housing along the open side and holds plural nozzles selectively alignable with said sprinkler body. An actuator is arranged to move a selected one of the plural nozzles from the nozzle magazine into the sprinkler body.

Abstract: A stream redirecting device for a sprinkler comprising a shell-shaped body having a generally semi-circular shape in plan, with opposite inlet and outlet side edges, said body extending outwardly and upwardly from a base at a lower end and then upwardly and inwardly to a distal, arcuate edge at an upper end, with a maximum radius between said base and said arcuate edge; an inside surface of said shell-shaped body formed with a plurality of grooves between said inlet side edge and said outlet side edge, extending in a generally radial direction with entry ends adjacent said base and exit ends at said distal, arcuate edge; and wherein said grooves are formed with circumferential exit angles that vary substantially uniformly in opposite directions from a center one of said plurality of grooves to first and last of said plurality of grooves at said opposite inlet and outlet side edges, respectively.

Abstract: Subject matter disclosed herein relates to a process for reviewing electronic content.

Abstract: A rotary pinch valve includes a valve body having an inlet and an outlet; the valve body supporting a pinch tube and a pair of pivotally mounted pinch arms, the pinch tube forming part of an axial flowpath from said inlet to said outlet. A valve actuator dial is received on the valve body and formed with a pair of internal cam lobes engageable, respectively, with cam follower surfaces on each of the pair of pivotally mounted pinch arms upon rotation of the valve actuator dial to pivot the pair of pinch arms from an open position out of engagement with the pinch tube to a closed position where the pinch arms engage and close the pinch tube to thereby shut off flow through the valve body.

Abstract: A method of controlling rotation of a water distribution plate supported on a shaft and adapted to rotate about an axis defined by the shaft by reason of impingement of a stream emitted from a nozzle on grooves formed in the plate, the method includes: (a) slowing the rotation of the water distribution plate intermittently so as to create intervals of relatively slow and relatively fast rotation and thereby correspondingly increase and decrease, respectively, a radius of throw of the stream or improve the uniformity of water distribution; and (b) continually changing circumferential locations of the intervals about the axis.

Abstract: Briefly, one or more embodiments of a process, system, apparatus or article to edit electronic content is provided. Electronic content may be displayed in an application. A snapshot of a portion of the electronic content may be created. An edit and/or a comment may be received that provides context for the comment. A review that includes the snapshot and edit and/or comment may be published to one or more recipients. At least one of the one or more recipients may be configured to receive the review and display the review using a different application.