Patents by Inventor Michael Trendelenburg

Michael Trendelenburg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and apparatus for multiple labeling detection and evaluation of a plurality of particles
    Publication number: 20060210129
    Abstract: The invention relates to a transmission electron microscope equipped with a 2k?2k pixel area Slow Scan Cooled Charge Coupled Device Camera connected to an image processing software for generating an image of a sample. A segmentation of gold particles in the sample is achieved by the separation from specimen structure and background noise. An identification and classification of particle types is carried out according to the shape and size of the detected particles or particle pairs and finally, the gold particle distribution is visualized by the generation of false color overlay images as well as the indication of the numbers in the image.
    Type: Application
    Filed: July 30, 2003
    Publication date: September 21, 2006
    Applicant: DEUTSCHES KREBSFORSCHUNGZENTRUM
    Inventors: Michael Trendelenburg, Herbert Spring, Luiz Monteiro-Leal, Loraine Campanati-Araujo, Helmut Troester
  • Molecular-biological marker for analytical electron microscopy
    Patent number: 6743584
    Abstract: The invention relates to plasmids derived from pBluescript KS(+), which contains more than 1, preferably 2, 7, 14, 21 and 27, respective SK primer elements, and their use in analytical electron microscopy.
    Type: Grant
    Filed: March 1, 2002
    Date of Patent: June 1, 2004
    Assignee: Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts
    Inventors: Sabine Bub, Helmut Troester, Karsten Richter, Ansgar Haking, Stefan Raddatz, Manfred Wiessler, Eberhard Spiess, Michael Trendelenburg
  • Method for enhancing the contrast for a transmission electron microscope
    Patent number: 6563112
    Abstract: The intention is to provide a process for the contrast enhancement of a specific particle in an image of a specimen, taken by a transmission electron microscope, in which a calculated contrast-rich image is created by way of the background intensities calculated from the intensities of a first image being drawn off pixel by pixel, whereby the background intensities are calculated as a function of the intensities of a second image. In this situation, it is intended that this process should feature a higher range of application than processes known hitherto, and, in particular, are well-suited for contrast enhancement for gold particles in immuno-gold marking.
    Type: Grant
    Filed: October 27, 2000
    Date of Patent: May 13, 2003
    Assignee: Deutsches Krebsforschungszentrum Stiftung Des Öffentlichen Rechts
    Inventors: Ansgar Haking, Helmut Tröster, Karsten Richter, Michael Trendelenburg
  • Compounds containing boron for energy-filtering transmission electron microscopy and for boron neutron-capture therapy
    Patent number: 6521604
    Abstract: The invention relates to a compound which contains boron and which comprises the following general formula (1) in which Cb represents carborane, R2 and R3, independent of one another, represent a hydrogen atom or an organic radical, and R and R1, independent of one another, represent a hydrogen atom or an organic group, or R and R1 form a carbonyl group with the carbon atom to which they are bound. The invention also relates to a method of producing a compound containing boron and to the application of the same.
    Type: Grant
    Filed: December 15, 2000
    Date of Patent: February 18, 2003
    Assignee: Deutches Krebsforschungszentrum
    Inventors: Manfred Wiessler, Helmut Tröster, Stefan Raddatz, Eberhard Spiess, Michael Trendelenburg