Abstract: A cleaning device for disinfecting a Luer access device includes a housing and a cleaning material. The housing has an opening and elastomeric sidewalls defining an inner cavity. The elastomeric sidewalls are configured to deform and conform to respective surface features of the Luer access device. The cleaning material is positioned within the inner cavity and carries a disinfectant. The cleaning device is configured to removably engage the Luer access device, and the cleaning material is configured to contact at least a portion of the Luer access device when the cleaning device is engaged with the Luer access device.

Abstract: The present disclosure provides wound-treating absorbent kits that comprise a set of hemostatic compositions including at least (1) a first hemostatic composition including a first crosslinked polysaccharide selected from the group consisting of cyclodextrin and dextran, and (2) a second hemostatic composition including a second crosslinked polysaccharide selected from the group consisting of cyclodextrin and dextran. In some embodiments, the first hemostatic composition has a first degree of crosslinking, and the second hemostatic composition has a second degree of crosslinking higher than the first degree of crosslinking. Also provided are methods of treating a wound by selecting a hemostatic composition from the disclosed set of hemostatic compositions, and administering the selected hemostatic composition to a site of the wound.

Abstract: A cleaning device for disinfecting a Luer access device includes a housing and a cleaning material. The housing has an opening and elastomeric sidewalls defining an inner cavity. The elastomeric sidewalls are configured to deform and conform to respective surface features of the Luer access device. The cleaning material is positioned within the inner cavity and carries a disinfectant. The cleaning device is configured to removably engage the Luer access device, and the cleaning material is configured to contact at least a portion of the Luer access device when the cleaning device is engaged with the Luer access device.

Abstract: The present disclosure provides methods of improving adhesion of a non-di-(2-ethylhexyl)phthalate (DEHP) plasticized polyvinyl chloride (PVC) to an acrylic-based polymer or an ABS-based polymer. Such methods may comprise blending the acrylic-based polymer or ABS-based polymer with an impact modifier so that a rubber content in the acrylic-based polymer or ABS-based polymer is greater than 12% (w/w). Also provided are components of a device (e.g., a medical device) made by the disclosed methods.

Abstract: The present disclosure provides methods of improving adhesion of a non-di-(2-ethylhexyl)phthalate (DEHP) plasticized polyvinyl chloride (PVC) to an acrylic-based polymer or an ABS-based polymer. Such methods may comprise blending the acrylic-based polymer or ABS-based polymer with an impact modifier so that a rubber content in the acrylic-based polymer or ABS-based polymer is greater than 12% (w/w). Also provided are components of a device (e.g., a medical device) made by the disclosed methods.

Abstract: Disclosed are PVC compositions with enhanced color resistance to electromagnetic irradiation & shelf life color stability; gamma-irradiated PVC articles; methods of making the gamma-irradiated PVC articles; and compositions including PVC resins for making the gamma-irradiated PVC articles.

Abstract: Methods for making antimicrobial resins and for forming coatings comprising antimicrobial resins on substrate surfaces are disclosed. The methods involve providing a mixture comprising about 15 weight % to about 80 weight % of a hydrophilic acrylic oligomer, about 10 weight % to about 80 weight % of a multifunctional acrylic monomer, about 5 weight % to about 40 weight % of an adhesion-promoting acrylic or vinyl monomer, and about 0.1 weight % to about 15 weight % of a metal salt; and exposing the mixture to a radiation source to cure at least a portion of the mixture, thereby forming an antimicrobial resin.

Abstract: A medical device, such as a vascular access device, is disclosed for providing access to a medical fluid flow path for the introduction or withdrawal of medical fluids to and from the flow path. The access device includes an indicator for providing a visual indication when the access device has been exposed to an antiseptic agent.

Abstract: Methods for making antimicrobial resins and for forming coatings comprising antimicrobial resins on substrate surfaces are disclosed. The methods involve providing a mixture comprising about 15 weight % to about 80 weight % of a hydrophilic acrylic oligomer, about 10 weight % to about 80 weight % of a multifunctional acrylic monomer, about 5 weight % to about 40 weight % of an adhesion-promoting acrylic or vinyl monomer, and about 0.1 weight % to about 15 weight % of a metal salt; and exposing the mixture to a radiation source to cure at least a portion of the mixture, thereby forming an antimicrobial resin.

Abstract: Methods for making antimicrobial resins and for forming coatings comprising antimicrobial resins on substrate surfaces are disclosed. The methods involve providing a mixture comprising about 15 weight % to about 80 weight % of a hydrophilic acrylic oligomer, about 10 weight % to about 80 weight % of a multifunctional acrylic monomer, about 5 weight % to about 40 weight % of an adhesion-promoting acrylic or vinyl monomer, and about 0.1 weight % to about 15 weight % of a metal salt; and exposing the mixture to a radiation source to cure at least a portion of the mixture, thereby forming an antimicrobial resin.

Abstract: Films containing microlayer structures are provided. In a general embodiment, the present disclosure provides an autoclavable film containing a first microlayer of a heat resistant polymer and a second microlayer of a flexible polymer attached to the first microlayer. Each of the first microlayer and the second microlayer has a thickness ranging between about 0.01 microns and about 10 microns.

Abstract: Films containing microlayer structures are provided. In a general embodiment, the present disclosure provides a film containing a first microlayer of a heat resistant polymer and a second microlayer of a barrier polymer having a heat distortion temperature ranging between about 50° C. and about 120° C. attached to the first microlayer. Each of the first microlayer and the second microlayer has a thickness ranging from about 0.01 microns to about 10 microns.

Abstract: Multiple layer structures comprising one or more poly(vinylidene chloride) layers and containers made from the multiple layer structures are provided. In a general embodiment, the present disclosure provides a multiple layer structure comprising one or more PVDC layers comprising a component selected from the group consisting of a poly(vinylidene chloride), a poly(vinylidene chloride) copolymer, and combinations thereof. The multiple layer structure further comprises one or more tie layers attached to the PVDC layer. The tie layer comprises a component selected from the group consisting of (a) polyether polyester copolymers, (b) polyurethanes having a melting temperature above about 121° C., (c) a blend comprising a polyamide and an ethylene copolymer containing an amine reactive functional group, and combinations thereof.

Abstract: A medical device, such as a vascular access device, is disclosed for providing access to a medical fluid flow path for the introduction or withdrawal of medical fluids to and from the flow path. The access device includes an indicator for providing a visual indication when the access device has been exposed to an antiseptic agent.

Abstract: A medical device, such as a vascular access device, is disclosed for providing access to a medical fluid flow path for the introduction or withdrawal of medical fluids to and from the flow path. The access device includes an indicator for providing a visual indication when the access device has been exposed to an antiseptic agent.

Abstract: Films having peel seal layers and/or barrier layers are provided. In a general embodiment, the present disclosure provides a film comprising a barrier layer comprising a caprolactam-free nylon compound.

Abstract: Films having peel seal layers and/or barrier layers are provided. In a general embodiment, the present disclosure provides a film comprising a peel seal layer comprising a blend of a polypropylene random copolymer having a melting temperature greater than 145° C., a styrene-ethylene-butylene-styrene block copolymer, and an LLDPE having a melting temperature greater than 120° C.

Abstract: Multilayer films comprising a core layer are provided. In an embodiment, the present disclosure provides a film having a core layer comprising a material selected from a rubber-modified polypropylene and a polymer blend. The polymer blend includes an elastomeric propylene-ethylene copolymer and a component selected from the group consisting of polypropylene random copolymers, styrene/ethylene-butylene/styrene block copolymers, and combinations thereof.

Abstract: Methods for making antimicrobial resins and for forming coatings comprising antimicrobial resins on substrate surfaces are disclosed. The methods involve providing a mixture comprising about 15 weight % to about 80 weight % of a hydrophilic acrylic oligomer, about 10 weight % to about 80 weight % of a multifunctional acrylic monomer, about 5 weight % to about 40 weight % of an adhesion-promoting acrylic or vinyl monomer, and about 0.1 weight % to about 15 weight % of a metal salt; and exposing the mixture to a radiation source to cure at least a portion of the mixture, thereby forming an antimicrobial resin.

Abstract: Films containing microlayer structures are provided. In a general embodiment, the present disclosure provides a film containing a first microlayer of a heat resistant polymer and a second microlayer of a barrier polymer having a heat distortion temperature ranging between about 50° C. and about 120° C. attached to the first microlayer. Each of the first microlayer and the second microlayer has a thickness ranging from about 0.01 microns to about 10 microns.