Patents by Inventor Michael Unbehauen

Michael Unbehauen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Analgesic preparation with nanocarriers and use thereof
    Patent number: 11253599
    Abstract: The invention relates to the field of analgesics. According to the invention, a kit or composition, particularly a pharmaceutical composition or a pharmaceutical kit, is provided, comprising a nanocarrier which is a hyperbranched polymer, such as a dendritic polymer or dendrimer, preferably having a molecular weight of 1,000-100,000 g/mol, and an analgesic which, when administered without nanocarrier, has both peripheral and central analgesic effect, preferably an opioid such as nalbuphine. According to the invention, the analgesic in this composition mainly or exclusively has a peripheral effect and thus reduces side effects triggered by the activation of central or intestinal opioid receptors. It is used for the treatment of peripheral pain and/or inflammation. The invention also relates to particularly suitable nanocarriers.
    Type: Grant
    Filed: December 8, 2016
    Date of Patent: February 22, 2022
    Assignee: DendroPharm GmbH
    Inventors: Emanuel Fleige, Sam Moré, Michael Unbehauen, Rainer Haag, Christoph Stein, Halina Machelska-Stein, Florian Paulus
  • ANALGESIC PREPARATION WITH NANOCARRIERS AND USE THEREOF
    Publication number: 20180344857
    Abstract: The invention relates to the field of analgesics. According to the invention, a kit or composition, particularly a pharmaceutical composition or a pharmaceutical kit, is provided, comprising a nanocarrier which is a hyperbranched polymer, such as a dendritic polymer or dendrimer, preferably having a molecular weight of 1,000-100,000 g/mol, and an analgesic which, when administered without nanocarrier, has both peripheral and central analgesic effect, preferably an opioid such as nalbuphine. According to the invention, the analgesic in this composition mainly or exclusively has a peripheral effect and thus reduces side effects triggered by the activation of central or intestinal opioid receptors. It is used for the treatment of peripheral pain and/or inflammation. The invention also relates to particularly suitable nanocarriers.
    Type: Application
    Filed: December 8, 2016
    Publication date: December 6, 2018
    Inventors: Emanuel Fleige, Sam Moré, Michael Unbehauen, Rainer Haag, Christoph Stein, Halina Machelska-Stein, Florian Paulus