Abstract: Automated detection of head and/or head-affecting body impact events in data collected is performed using instrumented mouthguard devices. For example, in some embodiments the present disclosure relates to training and operation of an impact classifier system, which is configured to identify head affecting impacts from time-series data collected by an instrumented mouthguard device. Some embodiments relate to a two-stage method for processing impacts, including a first stage in which a set of data is classified by such an impact classifier system, and a second stage whereby impacts classified as head affecting impacts are designated a numerical value based on a predefined scale.

Abstract: Technology facilitates dynamic variability of head impact data recordal, for example, in the context of instrumented mouthguard devices. Some embodiments have been developed to facilitate an event recoding protocol that dynamically adjusts event recoding parameters thereby to provide appropriate data for both “short” and “prolonged” impact events. For example, various embodiments include methods for recording impact events in respect of an instrumented mouthguard device, such methods including dynamically adjusting a period of time for which event data is recorded for a given event responsive to length of time for which an over-threshold condition persists.

Abstract: Improved assessment of brain injuries, and improved brain injury management, is achieved using a combination of impact-related data derived from instrumented mouthguard devices, human function performance testing, and biomarkers derived from biological fluid (such as saliva and/or blood). The human function performance testing may include brain function performance testing, and/or other forms of human function performance testing. This involves combining a data-driven understanding of a head impact event (based on data collected via an instrumented mouthguard device) with a data-driven understanding of human function performance following that head impact event. The biomarkers may include salivary mRNA and/or ncRNA, and/or blood proteins (for example via a FDA-approved Brain Trauma Indicator test).

Abstract: The present disclosure relates to technology adapted for improved assessment of brain injuries in a human subject. For example, in some embodiments the invention relates to improved processing of data collected via an instrumented mouthguard device, including identification of false impacts. It will be appreciated that the invention is not limited to such a field of use, and is applicable in broader contexts. For example, the technology may be applied to detect other changes in physical performance, beyond head injuries. Furthermore, the technology may be applied in respect of other wearable devices which detect/measure head impacts, for example helmets.

Abstract: Instrumented mouthguards include components such as accelerometer modules that enable monitoring of head movements of a mouthguard wearer. Various embodiments that provide instrumented mouthguard devices and components configured for use in instrumented mouthguard devices, including flexible circuit board substrates. In some embodiments, the flexible circuit board substrate is configured to allow sizing irregularities resultant from customization of the mouthguard body to a specific wearer.

Abstract: Technology disclosed herein relates to sensor-enabled mouthguards. Embodiments have been particularly developed to provide sensor-enabled mouthguards configured to enable monitoring of head impact data via multiple accelerometers, and data processing methods configured to analyse data derived from multiple accelerometers carried by a sensor-enabled mouthguard. This finds application, for example, in the context of managing brain injury risks in the context of sporting activities.

Abstract: Technology disclosed herein relates to monitoring of effects relevant to head impacts and/or injuries in humans. Embodiments of the invention have been particularly developed for enabling real-time monitoring of head impact data for participants in contact sports systems. This finds application, for example, in the context of managing brain injury risks in the context of sporting activities.