Abstract: The invention relates to a filter device for the exchange of substances, comprising a pipe section-shaped housing with a center of gravity and with two housing ends, in which housing a hollow fiber bundle consisting of semi-permeable membranes is arranged, comprising, furthermore, an end cap having a first and second opening, wherein the housing and the end cap configure a first sealing surface which connects the housing and the end cap sealingly, and wherein the first sealing surface is spaced apart further from the center of gravity of the housing than the aperture, and wherein a first fluid chamber is formed between the first sealing surface and the first opening of the end cap, via which first fluid chamber the first opening is connected to the first flow chamber, wherein the housing and the one end cap configure a second sealing surface, wherein the first and second sealing surface are not configured by way of a sealant.

Abstract: An apparatus for conveying thick matter has a drive cylinder for receiving hydraulic fluid, a drive piston, which is arranged in the drive cylinder, a conveying cylinder for receiving thick matter, a conveying piston, which is arranged in the conveying cylinder, and a piston rod, which is fastened to the drive piston for coupling motion together with the conveying piston. The drive cylinder has a rod-side opening for applying pressure to a rod side of the drive piston by way of hydraulic fluid and a crown-side opening for applying pressure to a crown side of the drive piston facing away from the rod side by the hydraulic fluid. A drive pump is designed to generate a drive volume flow having a drive pressure of hydraulic fluid for moving the drive piston. A pump connection is designed for variable connection of the drive pump to the rod-side opening or the crown-side opening for the flow of hydraulic fluid.

Abstract: A drive unit of a top drive system includes a drive stem having a plurality of ports from an exterior thereof to an interior thereof. A plurality of sliding coupling members is disposed in the ports. A coupling collar encircles the drive stem and has actuation surfaces and recessed surfaces on an interior thereof, wherein the recessed surfaces align with the ports when the coupling collar is in a first position, and the actuation surfaces align with the ports when the coupling collar is in a second position.

Abstract: It is provided a method for manufacturing viruses in an in vitro cell culture. The method comprising the following steps: providing a cell culture of avian epithelial cells chosen from at least one of the cell cultures deposited under deposition numbers DSM ACC3345, DSM ACC3346, DSM ACC3347, DSM ACC3348, DSM ACC3349 at Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen and Zellkulturen GmbH on Dec. 12, 2018; infecting at least some of the cells in the cell culture with virus particles; incubating the cells for a first period of time; and recovering viruses produced by the cell culture from a supernatant of the cell culture.