Abstract: A microfluidic system may include a microfluidic chip having a non-conductive substrate and wells connected in common to a microfluidic channel within the non-conductive substrate. Each well may have a galvanic contact with a first portion at an upper surface of the sample well and a second portion that extends into the non-conductive substrate. A plurality of electrodes may be provided as part of an electrical interface, with each electrode configured to contact a respective galvanic contact of the microfluidic chip. The electrical interface may also include at least one shared power amplifier that is configured to generate a power signal (e.g., constant current, constant voltage, pulsed power signal). A selector may be configured to receive the generated power signal from the shared power amplifier and configured to select at least one of the plurality of electrodes and output the received power signal thereto.