Patents by Inventor Michael W. Kaiser

Michael W. Kaiser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DETECTING BREAST CANCER
    Publication number: 20260201478
    Abstract: Provided herein is technology for breast cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of breast cancer.
    Type: Application
    Filed: January 6, 2026
    Publication date: July 16, 2026
    Inventors: David A. Ahlquist, William R. Taylor, Douglas W. Mahoney, Tracy C. Yab, John B. Kisiel, Hatim T. Allawi, Graham P. Lidgard, Michael W. Kaiser
  • DETECTING OVARIAN CANCER
    Publication number: 20260078450
    Abstract: Provided herein is technology for ovarian cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of ovarian cancer and sub-types of ovarian cancer (e.g., clear cell ovarian cancer, endometrioid ovarian cancer, mucinous ovarian cancer, serous ovarian cancer).
    Type: Application
    Filed: October 6, 2025
    Publication date: March 19, 2026
    Inventors: William R. Taylor, John B. Kisiel, Douglas W. Mahoney, David A. Ahlquist, Hatim T. Allawi, Michael W. Kaiser
  • Isolation and detection of DNA from plasma
    Patent number: 12571025
    Abstract: Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the sample DNA. The technology further provides methods for isolating DNA from blood or blood product samples, e.g., plasma samples.
    Type: Grant
    Filed: May 1, 2023
    Date of Patent: March 10, 2026
    Assignee: EXACT SCIENCES CORPORATION
    Inventors: Hatim Allawi, Graham P. Lidgard, Brian Aizenstein, Tamara J. Sander, Maria Giakoumopoulos, Michael W. Kaiser, Melissa M. Gray, Abram Michael Vaccaro
  • Detecting breast cancer
    Patent number: 12540360
    Abstract: Provided herein is technology for breast cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of breast cancer.
    Type: Grant
    Filed: February 17, 2021
    Date of Patent: February 3, 2026
    Assignees: Mayo Foundation for Medical Education and Research, Exact Sciences Corporation
    Inventors: David A. Ahlquist, William R. Taylor, Douglas W. Mahoney, Tracy C. Yab, John B. Kisiel, Hatim T. Allawi, Graham P. Lidgard, Michael W. Kaiser
  • LOW-BIAS SEQUENTIAL MULTIPLEX AMPLIFICATION ASSAYS
    Publication number: 20250333781
    Abstract: Provided herein is technology relating to multiplex preamplification of multiple different target nucleic acids from a sample, e.g., an environmental or biological sample, and particularly, but not exclusively, to methods, compositions, kits, and related uses for detecting and assessing mixtures of target nucleic acids, e.g.. The technology provides methods, compositions, and kits for using low-bias amplification conditions to perform highly-multiplexed preamplification followed by highly-multiplexed detection assays such as PCR assays, next generation sequencing assays, and PCR-flap assay for assaying samples that comprise multiple different target nucleic acids.
    Type: Application
    Filed: April 27, 2023
    Publication date: October 30, 2025
    Inventors: Gracie Shea, Abram M. Vaccaro, Cynthia Moehlenkamp, Hatim T. Allawi, Viatcheslav Katerov, Michael W. Kaiser
  • DETECTING BREAST CANCER
    Publication number: 20250327134
    Abstract: Provided herein is technology for breast cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of breast cancer.
    Type: Application
    Filed: May 6, 2025
    Publication date: October 23, 2025
    Inventors: David A. Ahlquist, William R. Taylor, Douglas W. Mahoney, Tracy C. Yab, John B. Kisiel, Hatim T. Allawi, Graham P. Lidgard, Michael W. Kaiser
  • Detecting ovarian cancer
    Patent number: 12442043
    Abstract: Provided herein is technology for ovarian cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of ovarian cancer and sub-types of ovarian cancer (e.g., clear cell ovarian cancer, endometrioid ovarian cancer, mucinous ovarian cancer, serous ovarian cancer).
    Type: Grant
    Filed: June 1, 2023
    Date of Patent: October 14, 2025
    Assignees: Mayo Foundation for Medical Education and Research, Exact Sciences Corporation
    Inventors: William R. Taylor, John B. Kisiel, Douglas W. Mahoney, David A. Ahlquist, Hatim T. Allawi, Michael W. Kaiser
  • Detecting breast cancer
    Patent number: 12325878
    Abstract: Provided herein is technology for breast cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of breast cancer.
    Type: Grant
    Filed: March 18, 2021
    Date of Patent: June 10, 2025
    Assignees: Mayo Foundation for Medical Education and Research, Exact Sciences Corporation
    Inventors: David A. Ahlquist, William R. Taylor, Douglas W. Mahoney, Tracy C. Yab, John B. Kisiel, Hatim T. Allawi, Graham P. Lidgard, Michael W. Kaiser
  • Multiplex Amplification Detection Assay II
    Publication number: 20250146062
    Abstract: Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the sample DNA. The technology further provides methods for isolating DNA from blood or blood product samples, e.g., plasma samples.
    Type: Application
    Filed: November 12, 2024
    Publication date: May 8, 2025
    Inventors: Hatim T. Allawi, William G. Weisburg, Graham P. Lidgard, Michael W. Kaiser, Abram M. Vaccaro, Gracie Shea
  • DETECTION OF LUNG NEOPLASIA BY AMPLIFICATION OF RNA SEQUENCES
    Publication number: 20250066858
    Abstract: Provided herein is technology for lung neoplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of lung cancer.
    Type: Application
    Filed: August 14, 2024
    Publication date: February 27, 2025
    Inventors: Hatim Allawi, Graham P. Lidgard, Chateen Krueger, Michael W. Kaiser, Tamara J. Sander
  • DETECTION OF COLON NEOPLASIA BY ANALYSIS OF METHYLATED DNA
    Publication number: 20250027158
    Abstract: Provided herein is technology for neoplasia screening, and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of cancer, in particular, colorectal cancer.
    Type: Application
    Filed: June 17, 2024
    Publication date: January 23, 2025
    Inventors: Hatim T. Allawi, Michael W. Kaiser, Graham P. Lidgard, William R. Taylor, Tamara J. Sander, Abram M. Vaccaro
  • Multiplex amplification detection assay II
    Patent number: 12173362
    Abstract: Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the sample DNA. The technology further provides methods for isolating DNA from blood or blood product samples, e.g., plasma samples.
    Type: Grant
    Filed: November 5, 2021
    Date of Patent: December 24, 2024
    Assignee: Exact Sciences Corporation
    Inventors: Hatim T. Allawi, William G. Weisburg, Graham P. Lidgard, Michael W. Kaiser, Abram M. Vaccaro, Gracie Shea
  • Detection of lung neoplasia by amplification of RNA sequences
    Patent number: 12098431
    Abstract: Provided herein is technology for lung neoplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of lung cancer.
    Type: Grant
    Filed: September 15, 2022
    Date of Patent: September 24, 2024
    Assignee: Exact Sciences Corporation
    Inventors: Hatim Allawi, Graham P. Lidgard, Chateen Krueger, Michael W. Kaiser, Tamara J. Sander
  • Detection of colon neoplasia by analysis of methylated DNA
    Patent number: 12049671
    Abstract: Provided herein is technology for neoplasia screening, and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of cancer, in particular, colorectal cancer.
    Type: Grant
    Filed: August 23, 2021
    Date of Patent: July 30, 2024
    Assignees: Exact Sciences Corporation, Mayo Foundation for Medical Education and Research
    Inventors: Hatim T. Allawi, Michael W. Kaiser, Graham P. Lidgard, William R. Taylor, Tamara J. Sander, Abram M. Vaccaro
  • DETECTING OVARIAN CANCER
    Publication number: 20240182976
    Abstract: Provided herein is technology for ovarian cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of ovarian cancer and sub-types of ovarian cancer (e.g., clear cell ovarian cancer, endometrioid ovarian cancer, mucinous ovarian cancer, serous ovarian cancer).
    Type: Application
    Filed: June 1, 2023
    Publication date: June 6, 2024
    Inventors: William R. Taylor, John B. Kisiel, Douglas W. Mahoney, David A. Ahlquist, Hatim T. Allawi, Michael W. Kaiser
  • ISOLATION AND DETECTION OF DNA FROM PLASMA
    Publication number: 20230392189
    Abstract: Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the sample DNA. The technology further provides methods for isolating DNA from blood or blood product samples, e.g., plasma samples.
    Type: Application
    Filed: May 1, 2023
    Publication date: December 7, 2023
    Inventors: Hatim Allawi, Graham P. Lidgard, Brian Aizenstein, Tamara J. Sander, Maria Giakoumopoulos, Michael W. Kaiser, Melissa M. Gray, Abram Michael Vaccaro
  • Detecting ovarian cancer
    Patent number: 11702704
    Abstract: Provided herein is technology for ovarian cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of ovarian cancer and sub-types of ovarian cancer (e.g., clear cell ovarian cancer, endometrioid ovarian cancer, mucinous ovarian cancer, serous ovarian cancer).
    Type: Grant
    Filed: October 30, 2020
    Date of Patent: July 18, 2023
    Assignees: Mayo Foundation for Medical Education and Research, Exact Sciences Corporation
    Inventors: William R. Taylor, John B. Kisiel, Douglas W. Mahoney, David A. Ahlquist, Hatim T. Allawi, Michael W. Kaiser
  • Isolation and detection of DNA from plasma
    Patent number: 11674168
    Abstract: Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the sample DNA. The technology further provides methods for isolating DNA from blood or blood product samples, e.g., plasma samples.
    Type: Grant
    Filed: September 24, 2020
    Date of Patent: June 13, 2023
    Assignee: Exact Sciences Corporation
    Inventors: Hatim Allawi, Graham P. Lidgard, Brian Aizenstein, Tamara J. Sander, Maria Giakoumopoulos, Michael W. Kaiser, Melissa M. Gray, Abram Michael Vaccaro
  • Detecting breast cancer
    Patent number: RE50621
    Abstract: Provided herein is technology for breast cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of breast cancer.
    Type: Grant
    Filed: May 3, 2022
    Date of Patent: October 7, 2025
    Assignees: Mayo Foundation for Medical Education and Research, Exact Sciences Corporation
    Inventors: David A. Ahlquist, William R. Taylor, Douglas W. Mahoney, Tracy C. Yab, John B. Kisiel, Hatim T. Allawi, Graham P. Lidgard, Michael W. Kaiser
  • Detecting breast cancer
    Patent number: RE50806
    Abstract: Provided herein is technology for breast cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of breast cancer.
    Type: Grant
    Filed: May 3, 2022
    Date of Patent: February 24, 2026
    Assignees: Mayo Foundation for Medical Education and Research, Exact Sciences Corporation
    Inventors: David A. Ahlquist, William R. Taylor, Douglas W. Mahoney, Tracy C. Yab, John B. Kisiel, Hatim T. Allawi, Graham P. Lidgard, Michael W. Kaiser