Abstract: Media and devices, such as anion exchangers including such media, wherein the media is a membrane having a surface coated with a polymer such as a polyallylamine. The resulting membrane offers stronger binding of protein impurities and superior removal of host cell proteins from biological samples than conventional ligands based on quaternary ammonium salts, including trimethylammonium ligands. Also described is a chromatography scheme and method for purifying monoclonal antibodies, wherein the anion exchange sorber is placed downstream of an affinity column (such as Protein A or Protein G affinity column) and optionally one or more polishing devices such as cationic exchange columns. Little or no dilution of the cation exchanger pool (or affinity column exchange pool where no cation exchanger is used) is necessary to lower the conductivity of the sample. The sorber functions well to strongly bind host cell proteins and other impurities in biological samples even at high conductivities and pH.

Abstract: An electrical assembly selectively receives power from an external power supply. The electrical assembly includes a base that at least partially defines a tool port and a battery port and an electrical tool selectively coupled to the tool port. A rechargeable battery pack is selectively coupled to the battery port and a circuit is supported by the base and is operable to direct power to the tool port and the battery port such that the external power provides power to the electrical tool to operate the electrical tool and to recharge the rechargeable battery pack.

Abstract: A power tool includes a housing having a handle configured for a user, the handle defining a first axis, a motor supported by the housing, the motor defining a second axis along a length of the motor, a tool element movably supported by the housing and drivingly coupled to the motor, the tool element defining a third axis along a length of the tool element. Each of the first, second, and third axes are oblique with respect to each of the other axes.

Abstract: A level includes a first planar surface having a first longitudinal edge and a second longitudinal edge and a second planar surface having a third longitudinal edge and a fourth longitudinal edge. The first longitudinal edge and the third longitudinal edge define a first side plane and the second longitudinal edge and the fourth longitudinal edge define a second side plane. A vial has a long axis and contains a liquid and a gas bubble. A web is coupled to the first and second planar surfaces such that the first and second planar surfaces are spaced apart from and parallel to each other. The web includes a first side surface on the first plane and a second side surface. A first recess pattern is arranged to engage a first electrical component and a second recess pattern is arranged to engage a second electrical component.

Abstract: A power tool includes a housing having a handle configured for a user, the handle defining a first axis, a motor supported by the housing, the motor defining a second axis along a length of the motor, a tool element movably supported by the housing and drivingly coupled to the motor, the tool element defining a third axis along a length of the tool element. Each of the first, second, and third axes are oblique with respect to each of the other axes.

Abstract: A pliers that includes a jaw member removably coupled to a head of the pliers. The jaw member includes a grip surface and a flange including an aperture. The pliers further includes a fastener that extends into the aperture of the flange and an aperture of a longitudinal side of the head to removably couple the jaw member to the head. The jaw member is slidable along the jaw surface of the head from the first longitudinal side toward the second longitudinal side to uncouple the jaw member from the head when the fastener is uncoupled from at least one of the jaw member and the head.

Abstract: A power tool includes a housing having a handle configured for a user, the handle defining a first axis, a motor supported by the housing, the motor defining a second axis along a length of the motor, a tool element movably supported by the housing and drivingly coupled to the motor, the tool element defining a third axis along a length of the tool element. Each of the first, second, and third axes are oblique with respect to each of the other axes.

Abstract: A level for indicating the orientation of a surface includes a first planar surface, a second planar surface, and a web coupled to the first planar surface and the second planar surface such that the first planar surface is spaced apart from and is parallel to the second planar surface. A vial defines a long axis and contains a liquid and a gas bubble. The vial is coupled to the web such that the long axis is substantially parallel to the first planar surface. A tube deburring portion is coupled to the web and includes a male conical portion arranged to deburr an inner edge of a tube and a female conical portion arranged to deburr an outer edge of the tube.

Abstract: A pliers that includes a jaw member removably coupled to a head of the pliers. The jaw member includes a grip surface and a flange including an aperture. The pliers further includes a fastener that extends into the aperture of the flange and an aperture of a longitudinal side of the head to removably couple the jaw member to the head. The jaw member is slidable along the jaw surface of the head from the first longitudinal side toward the second longitudinal side to uncouple the jaw member from the head when the fastener is uncoupled from at least one of the jaw member and the head.

Abstract: A level includes a first planar surface having a first longitudinal edge and a second longitudinal edge and a second planar surface having a third longitudinal edge and a fourth longitudinal edge. The first longitudinal edge and the third longitudinal edge define a first side plane and the second longitudinal edge and the fourth longitudinal edge define a second side plane. A vial has a long axis and contains a liquid and a gas bubble. A web is coupled to the first and second planar surfaces such that the first and second planar surfaces are spaced apart from and parallel to each other. The web includes a first side surface on the first plane and a second side surface. A first recess pattern is arranged to engage a first electrical component and a second recess pattern is arranged to engage a second electrical component.

Abstract: A pliers that includes a jaw member removably coupled to a head of the pliers. The jaw member includes a grip surface and a flange including an aperture. The pliers further includes a fastener that extends into the aperture of the flange and an aperture of a longitudinal side of the head to removably couple the jaw member to the head. The jaw member is slidable along the jaw surface of the head from the first longitudinal side toward the second longitudinal side to uncouple the jaw member from the head when the fastener is uncoupled from at least one of the jaw member and the head.

Abstract: Media and devices, such as anion exchangers including such media, wherein the media is a membrane having a surface coated with a polymer such as a polyallylamine. The resulting membrane offers stronger binding of protein impurities and superior removal of host cell proteins from biological samples than conventional ligands based on quaternary ammonium salts, including trimethylammonium ligands. Also described is a chromatography scheme and method for purifying monoclonal antibodies, wherein the anion exchange sorber is placed downstream of an affinity column (such as Protein A or Protein G affinity column) and optionally one or more polishing devices such as cationic exchange columns. Little or no dilution of the cation exchanger pool (or affinity column exchange pool where no cation exchanger is used) is necessary to lower the conductivity of the sample. The sorber functions well to strongly bind host cell proteins and other impurities even at high conductivities and pH.

Abstract: Media and devices, such as anion exchangers including such media, wherein the media is a membrane having a surface coated with a polymer such as a polyallylamine. The resulting membrane offers stronger binding of protein impurities and superior removal of host cell proteins from biological samples than conventional ligands based on quaternary ammonium salts, including trimethylammonium ligands. Also described is a chromatography scheme and method for purifying monoclonal antibodies, wherein the anion exchange sorber is placed downstream of an affinity column (such as Protein A or Protein G affinity column) and optionally one or more polishing devices such as cationic exchange columns. Little or no dilution of the cation exchanger pool (or affinity column exchange pool where no cation exchanger is used) is necessary to lower the conductivity of the sample. The sorber functions well to strongly bind host cell proteins and other impurities even at high conductivities and pH.

Abstract: An electrical combination includes a power tool having a body, a motor supported by the body, a support portion, and a drive mechanism driven by the motor such that the drive mechanism is operable to drive a tool element. The electrical combination also includes a battery operable for coupling to the power tool via the support portion. The battery is electrically connectable with the motor to selectively supply power to the motor. A single latch is positioned on the support portion of the power tool. The single latch is moveable between a locked position to secure the battery to the power tool and an unlocked position to allow removal of the battery from the support portion of the power tool.

Abstract: Media and devices, such as anion exchangers including such media, wherein the media is a membrane having a surface coated with a polymer such as a polyallylamine. The resulting membrane offers stronger binding of protein impurities and superior removal of host cell proteins from biological samples than conventional ligands based on quaternary ammonium salts, including trimethylammonium ligands. Also described is a chromatography scheme and method for purifying monoclonal antibodies, wherein the anion exchange sorber is placed downstream of an affinity column (e.g., Protein A or Protein G) and optionally one or more polishing devices such as cationic exchange columns. Little or no dilution of the cation exchanger pool (or affinity column exchange pool where no cation exchanger is used) is necessary to lower the conductivity of the sample. The sorber functions well to strongly bind host cell proteins and other impurities in biological samples even at high conductivities and pH.

Abstract: Media and devices, such as anion exchangers including such media, wherein the media is a membrane having a surface coated with a polymer such as a polyallylamine. The resulting membrane offers stronger binding of protein impurities and superior removal of host cell proteins from biological samples than conventional ligands based on quaternary ammonium salts, including trimethylammonium ligands. Also described is a chromatography scheme and method for purifying monoclonal antibodies, wherein the anion exchange sorber is placed downstream of an affinity column (such as Protein A or Protein G affinity column) and optionally one or more polishing devices such as cationic exchange columns. Little or no dilution of the cation exchanger pool (or affinity column exchange pool where no cation exchanger is used) is necessary to lower the conductivity of the sample. The sorber functions well to strongly bind host cell proteins and other impurities in biological samples even at high conductivities and pH.

Abstract: A pliers that includes a first member and a second member pivotally coupled to the first member. The pliers includes a head, a handle, a first end defining a nose of the head portion, and a second end, opposite the first end, defined by the handle of the pliers. Ridges are disposed on the first and the second members adjacent the nose and together define a grip of the pliers. Sharp edges of the first and second members are adjacent the ridges and between the ridges and the second end of the pliers and together define a cutter of the pliers. An aperture extends through the first member adjacent a pivot and between the pivot and the second end of the pliers, and the threaded aperture and the second member define a threaded fastener cutter of the pliers.

Abstract: A pliers that includes a jaw member removably coupled to a head of the pliers. The jaw member includes a grip surface and a flange including an aperture. The pliers further includes a fastener that extends into the aperture of the flange and an aperture of a longitudinal side of the head to removably couple the jaw member to the head. The jaw member is slidable along the jaw surface of the head from the first longitudinal side toward the second longitudinal side to uncouple the jaw member from the head when the fastener is uncoupled from at least one of the jaw member and the head.

Abstract: An electrical assembly selectively receives power from an external power supply. The electrical assembly includes a base that at least partially defines a tool port and a battery port and an electrical tool selectively coupled to the tool port. A rechargeable battery pack is selectively coupled to the battery port and a circuit is supported by the base and is operable to direct power to the tool port and the battery port such that the external power provides power to the electrical tool to operate the electrical tool and to recharge the rechargeable battery pack.

Abstract: Media and devices, such as anion exchangers including such media, wherein the media is a membrane having a surface coated with a polymer such as a polyallylamine. The resulting membrane offers stronger binding of protein impurities and superior removal of host cell proteins from biological samples than conventional ligands based on quaternary ammonium salts, including trimethylammonium ligands. Also described is a chromatography scheme and method for purifying monoclonal antibodies, wherein the anion exchange sorber is placed downstream of an affinity column (such as Protein A or Protein G affinity column) and optionally one or more polishing devices such as cationic exchange columns. Little or no dilution of the cation exchanger pool (or affinity column exchange pool where no cation exchanger is used) is necessary to lower the conductivity of the sample. The sorber functions well to strongly bind host cell proteins and other impurities in biological samples even at high conductivities and pH.