Patents by Inventor Michael Wadas

Michael Wadas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyridinone- and pyridazinone-based compounds and uses thereof
    Patent number: 11964960
    Abstract: The various examples presented herein are directed to compounds of the formula A-L1-Het1-L2-Cy1 or a pharmaceutical acceptable salt, polymorph, prodrug, solvate or clathrate thereof, wherein: A is cycloalkyl, aryl, arylalkyl or heterocyclyl; Het1 is heterocyclyl containing at least two heteroatoms; Cy1 is a heterocyclyl; L1 is a bond, alkyl, alkenyl or alkynyl linker; L2 is an acyl or alkyl linker; and A and Cy1 are different. The compounds are useful in the treatment of fibrotic diseases, abnormal vascular leak and pathological angiogenesis.
    Type: Grant
    Filed: March 8, 2019
    Date of Patent: April 23, 2024
    Assignees: Cornell University, Tri-Institutional Therapeutics Discovery Institute
    Inventors: Timothy Hla, Irina Jilishitz, Peter Meinke, Andrew Stamford, Michael Foley, Ayumu Sato, Yasufimi Wada, Yoshiyuki Fukase, Asato Kina, Hiroki Takahagi, Hideyuki Igawa, William J. Polvino
  • METHOD OF DETECTING A SUBSTANCE
    Publication number: 20220003760
    Abstract: A method of detecting a substance, wherein the method includes functionalizing a plurality of sensors, wherein the functionalizing the plurality of sensors comprises depositing a first material using a piezoelectrically actuated pipette system, wherein the first material includes a polymer, a receptor, and a solvent, wherein the solvent comprises dimethylformamide. The method further includes evaporating a solution of the first material, wherein a residue after the evaporation comprises a functionalized chemical. Additionally, the method includes introducing a control material to a first set of sensors of the plurality of sensors using the piezoelectrically actuated pipette system. Further, the method includes introducing a test material to a second set of sensors of the plurality of sensors using the piezoelectrically actuated pipette system, wherein the test material comprises an analyte.
    Type: Application
    Filed: February 10, 2021
    Publication date: January 6, 2022
    Applicant: Purdue Research Foundation
    Inventors: Jeffrey Frederick Rhoads, Eric A. Nauman, Mackenzie Tweardy, Michael Wadas, Allison Kelly Murray, George Tsu-Chih Chiu, Nikhil Bajaj
  • Method of detecting a substance
    Patent number: 10948489
    Abstract: A method of detecting a substance, wherein the method includes functionalizing a plurality of sensors, wherein the functionalizing the plurality of sensors comprises depositing a first material using a piezoelectrically actuated pipette system, wherein the first material includes a polymer, a receptor, and a solvent, wherein the solvent comprises dimethylformamide. The method further includes evaporating a solution of the first material wherein a residue after the evaporation comprises a functionalized chemical. Additionally, the method includes introducing a control material to a first set of sensors of the plurality of sensors using the piezoelectrically actuated pipette system. Further, the method includes introducing a test material to a second set of sensors of the plurality of sensors using the piezoelectrically actuated pipette system, wherein the test material comprises an analyte.
    Type: Grant
    Filed: July 19, 2018
    Date of Patent: March 16, 2021
    Assignee: Purdue Research Foundation
    Inventors: Jeffrey Frederick Rhoads, Eric A. Nauman, Mackenzie Tweardy, Michael Wadas, Allison Kelly Murray, George Tsu-Chih Chiu, Nikhil Bajaj
  • METHOD OF DETECTING A SUBSTANCE
    Publication number: 20190025296
    Abstract: A method of detecting a substance, wherein the method includes functionalizing a plurality of sensors, wherein the functionalizing the plurality of sensors comprises depositing a first material using a piezoelectrically actuated pipette system, wherein the first material includes a polymer, a receptor, and a solvent, wherein the solvent comprises dimethylformamide. The method further includes evaporating a solution of the first material wherein a residue after the evaporation comprises a functionalized chemical. Additionally, the method includes introducing a control material to a first set of sensors of the plurality of sensors using the piezoelectrically actuated pipette system. Further, the method includes introducing a test material to a second set of sensors of the plurality of sensors using the piezoelectrically actuated pipette system, wherein the test material comprises an analyte.
    Type: Application
    Filed: July 19, 2018
    Publication date: January 24, 2019
    Applicant: Purdue Research Foundation
    Inventors: Jeffrey Frederick Rhoads, Eric A. Nauman, Mackenzie Tweardy, Michael Wadas, Allison Kelly Murray, George Tsu-Chih Chiu, Nikhil Bajaj