Abstract: The present disclosure relates to 5-membered heteroaryl carboxamide compounds, which may disrupt Hepatitis B (HBV) core protein assembly. The present disclosure further relates to pharmaceutical compositions comprising 5-membered heteroaryl carboxamide compounds which may disrupt HBV core protein assembly. The present disclosure further relates to uses of 5-membered heteroaryl carboxamide compounds and pharmaceutical compositions thereof in methods of treating Hepatitis B (HBV) infection.

Abstract: The present disclosure provides, in part, cyclic urea thiazolyl compounds, and pharmaceutical compositions thereof, and methods of the treatment and prophylaxis of HSV infections.

Abstract: The present disclosure provides, in part, tricyclic compounds, and pharmaceutical compositions thereof, and methods of the treatment and prophylaxis of HSV infections.

Abstract: The present disclosure provides, in part, tricyclic compounds, and pharmaceutical compositions thereof, and methods of the treatment and prophylaxis of HSV infections.

Abstract: The present disclosure provides, in part, azetidine compounds, and pharmaceutical compositions thereof, and methods of the treatment and prophylaxis of HSV infections.

Abstract: A low-floor electric bus includes a plurality of battery packs mounted under the floor of such that the floor inside the bus between a front axle and a rear axle of the bus is substantially flat. Each battery pack may include an enclosure and multiple battery modules positioned within the enclosure. And, each battery module may include a plurality of battery cells electrically connected together.

Abstract: The present disclosure provides, in part, cyclic urea thiazolyl compounds, and pharmaceutical compositions thereof, and methods of the treatment and prophylaxis of HSV infections.

Abstract: The present disclosure provides, in part, benzothia(dia)zepine compounds, and pharmaceutical compositions thereof, and methods of treating Hepatitis B (HBV) and Hepatitis D (HDV) infections.

Abstract: The present disclosure involves continuous measurement of the likelihood of a semiconductor-process chemical to form wafer defects composed primarily of particle-precursor material. Specifically, this disclosure details methods to estimate the effects of terminal size and contact angle for droplets remaining on a wafer following a spin-dry process. In some examples, the methods involve tuning a liquid-to-aerosol-based measurement device to correlate the measurement value with the tendency of a chemical to form such defects.

Abstract: Systems and methods for charging an electric bus having a charging interface on its roof may include determining that an approaching bus is supposed to be charged at the charging station, lowering the charging head of the charging station to land on the roof of the bus, and moving the bus with the charge head on its roof to engage the charging head with the charging interface.

Abstract: A hybrid three-layer system is presented. The hybrid three-layer system includes a two-layer composite system and an additively manufactured third layer comprising a lattice structure. The composite layer system includes a metallic substrate, a structured surface, and a thermal protection system. The structured surface may be additively manufactured onto the metallic substrate and includes structured surface features formed to project above the metallic substrate. Each of the structured surface features are separated from adjacent structured surface features by grooves. The thermal protection coating may be thermally sprayed onto the structured surface and is bonded to each of the structured surface features. The lattice structure is in contact with a surface of the metallic substrate of the composite layer system.

Abstract: A battery assembly for a local use vehicle has outer walls, electrical contacts, and a communication connection, the battery providing a quantity of energy to power the local use vehicle, the electrical contacts of the battery configured and located for electrical contact with the first electrical contacts within the battery compartment when the battery is in a fully-inserted position within the battery compartment, the communication connection of the battery configured and located for wireless non-contact communication with the communication connection within the battery compartment when the battery is in a fully-inserted position within the battery compartment. The battery further includes a grasping point extending from one of the outer walls of the battery, the grasping point configured for being grasped by the end effector of the robotic device to thereby move the battery back and forth between the fully-inserted position and a removed position outside of the local use vehicle via the opening.

Abstract: A system and method are provided for powering a fleet of local use vehicles using batteries, the batteries being removable from the local use vehicles for charging. The system and method include moving one of the local use vehicles in a battery exchange location when the battery in the local use vehicle is in an uncharged state, removing the battery in the uncharged state from a battery compartment in the local use vehicle using a robotic device, and placing the battery in the uncharged state into a first charging bay within a charging repository using the robotic device, the charging repository configured with a plurality of the charging bays to simultaneously hold and to charge a plurality of the batteries, removing a battery in a charged state from a second bay in the charging repository using the robotic device, and placing the battery in the charged state into the battery compartment in the local use vehicle.

Abstract: A wireless communication system for batteries removably mountable in local use vehicles and chargeable in a charging repository includes a plurality of batteries, each battery having a housing; a first wireless communication device attached to an outer surface of the housing for receiving and transmitting data; and electrical contacts attached to the housing for selectively providing power to or from the battery. A plurality of second wireless communication devices is mountable to either a one of the local use vehicles or to a location in the charging repository for communication with one of the first wireless communication devices when in an adjacent communication orientation.

Abstract: A system and method for selectively charging removable batteries used for powering a fleet of local use vehicles may include placing and selectively charging batteries in a charging repository. Batteries are charged to an at least threshold charge level at which the batteries may be used to power a vehicle in a duty cycle. Charging can be managed based on at least one of fleet battery replacement needs and electrical cost optimization. The repository includes at least one rack in which batteries may be charged and a robotic device for moving batteries back and forth between the rack and the vehicles. Charging batteries within the repository and supplying them to vehicles that drive to the repository for battery exchange provides efficient spatial usage.

Abstract: The present disclosure provides, in part, 5-membered heteroaryl carboxamide compounds, and pharmaceutical compositions thereof, useful for disruption of HBV core protein assembly, and methods of treating Hepatitis B (HBV) infection.