Patents by Inventor Michael Walkowiak

Michael Walkowiak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nitro-.beta.-lactam antibiotics and processes for their preparation and use
    Patent number: 4029806
    Abstract: Penicillin and cephalosporin derivatives characterized by the presence of a nitroalkyl, nitrocycloalkyl, nitrophenylalkyl or nitroanilinoalkyl group in the side chain are antibacterial agents. The compounds, of which 6-(2-nitro-3,3-dimethylbutyrylamido)-penicillanic acid, 7-nitroacetamido-3-methyl-ceph-3-em-4-carboxylic acid, and 6-[D-.alpha.-(2-nitro-2-methylpropionylamido)phenylacetamido] pencillanic acid are typical embodiments, are prepared by reacting 6-amino-penicillanic acid, 7-amino-cephalosporanic acid (or derivative thereof) or an .alpha.-substituted-.alpha.-amino-acetamido-penicillanic acid with an appropriate nitrated carboxylic acid or an equivalent nitrated acylating agent.
    Type: Grant
    Filed: July 22, 1976
    Date of Patent: June 14, 1977
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Krohn, Karl Georg Metzger, Michael Preiss, Michael Walkowiak
  • Nitro-.beta.-lactam antibiotics and processes for their preparation and use
    Patent number: 4012518
    Abstract: Penicillin and cephalosporin derivatives characterized by the presence of a nitroalkyl, nitrocycloalkyl, nitrophenylalkyl or nitroanilinoalkyl group in the side chain are antibacterial agents. The compounds, of which 6-(2-nitro-3,3-dimethylbutyrylamido)-penicillanic acid, 7-nitroacetamido-3-methyl-ceph-3-em-4-carboxylic acid, and 6-[D-.alpha.-(2-nitro-2-methylpropionylamido)phenylacetamido]-penicillanic acid are typical embodiments, are prepared by reacting 6-amino-penicillanic acid, 7-amino-cephalosporanic acid (or derivative thereof) or an .alpha.-substituted-.alpha. -aminoacetamido-penicillanic acid with an appropriate nitrated carboxylic acid or an equivalent nitrated acylating agent.
    Type: Grant
    Filed: August 8, 1975
    Date of Patent: March 15, 1977
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Krohn, Karl Georg Metzger, Michael Preiss, Michael Walkowiak