Abstract: The subject matter of the present disclosure generally relates to techniques for neuromodulation that include applying energy (e.g., ultrasound energy) into an internal tissue to cause tissue displacement and identifying that the tissue displacement has occurred. In one embodiment, the presence of tissue displacement is associated with a desired therapeutic or physiological outcome, such as a change in a molecule of interest.

Abstract: A cooling support cushion (10) and method of forming same is provided. In particular, the present cooling support cushions and methods of producing the same make use of a plurality of surface coatings (32) to a base layer (20) to provide an extended cooling effect. The surface coating may be mixed and applied or may be applied as separated layers.

Abstract: Compounds and methods for activating Nrf2 by inhibiting KEAP1.

Abstract: In an embodiment, a method automatically determines a networked data center architecture. In the method, a database describing capabilities of a data center provider is assembled. The database describes capabilities of a plurality of data centers of the data center provider. A specification of requirements for the networked data center architecture is received. The specification describes data processing and connectivity requirements of a customer of a data center provider. The database is searched to determine a solution including a plurality of connections and data center that satisfy the specification. Based on the searching, the solution is output as a recommendation to provide the networked data center architecture. In another embodiment, options for a networked data center architecture are visualized. In yet another embodiment, API calls are made to provision the networked data center architecture.

Abstract: Systems and methods are provided for detecting unclassified hazards for a driver assistance system of a vehicle. The systems include a data storage device comprising map data, one or more sensors configured to generate sensor data indicative of one or more sensed objects in proximity to the vehicle, and a controller configured to, by one or more processors thereof, receive the map data and the sensor data, filter the sensor data to omit at least one of the sensed objects located outside of a bounding area that includes a portion of an adjacent lane next to a current lane in which the vehicle is operating, determine whether an unclassified hazard is present in the adjacent lane, and maintain operation of the vehicle in the current lane in response to a determination that the unclassified hazard is present in the adjacent lane.

Abstract: An electrical junction box (10) comprising: a housing (110) defining a chamber (120) with an entry port (130) for receiving an electrical cable; and at least one connection terminal (170) provided within the chamber (120) and configured to engage an exposed conductor end of the electrical cable, the at least one connection terminal (170) comprising a clamping mechanism (180) for connecting a conductor of the electrical cable to the electrical junction box (10); wherein the housing (110) comprises a main body portion (150) and a lid (160) movably coupled to the main body portion (150), the main body portion (150) and the lid (160) together forming the chamber (120) and the entry port (130), the lid (160) being movable relative to the main body portion (150) from an open position in which the chamber (120) is accessible and a closed position in which the chamber (120) is covered, wherein movement of the lid (160) from the open position to the closed position causes the clamping mechanism (180) to clamp the expo

Abstract: The present invention relates generally to compositions and methods for treating cancer, e.g. by using the compounds of formula (I). Provided herein are substituted bicyclic heteroaryl derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition of Calcium/calmodulin-dependent protein kinase kinase 2. Furthermore, the subject compounds and compositions are useful for the treatment of cancer.

Abstract: Devices, systems, and methods for reducing stress on a blood vessel are disclosed herein. A damping device (100) configured in accordance with embodiments of the present technology can include an anchoring member (104) coupled to a flexible, compliant damping member (102) including a generally tubular sidewall having an outer surface (115), an inner surface (113) defining a lumen configured to direct blood flow, a first end portion (106) and a second end portion (108), and a damping region (120) between the first and second end portions (106, 108). The inner and outer surfaces (113, 115) of the damping member (102) can be spaced apart by a distance that is greater at the damping region (120) than at either of the first or second end portions (106, 108).

Abstract: In an example, an adjustable clamp system includes a base, a clamp assembly, and a first eccentric bushing. The base includes an anchor portion configured to couple the base to a support structure, a first clamp-support portion extending from the anchor portion, and a second clamp-support portion extending from the anchor portion. The clamp assembly includes a clamp defining a bore, a first flange extending from a first side of the clamp and coupled to the first clamp-support portion, and a second flange extending from a second side of the clamp and coupled to the second clamp-support portion. The first eccentric bushing couples the first flange to the first clamp-support portion. The first eccentric bushing is rotatable relative to the first flange to translate the clamp assembly in a first direction relative to the base and adjust a distance between the clamp and the anchor portion of the base.

Abstract: Centroids are used for improving machine learning classification and information retrieval. A plurality of files are classified as malicious or not malicious based on a function dividing a coordinate space into at least a first portion and a second portion such that the first portion includes a first subset of the plurality of files classified as malicious. One or more first centroids are defined in the first portion that classify files from the first subset as not malicious. A file is determined to be malicious based on whether the file is located within the one or more first centroids.

Abstract: An artifact is received and features are extracted therefrom to form a feature vector. Thereafter, a determination is made to alter a malware processing workflow based on a distance of one or more features in the feature vector relative to one or more indicator centroids. Each indicator centroid specifying a threshold distance to trigger an action. Based on such a determination, the malware processing workflow is altered.

Abstract: Devices, systems, and methods for reducing stress on a blood vessel are disclosed herein. A damping device (100) configured in accordance with embodiments of the present technology can include an anchoring member (104) coupled to a flexible, compliant damping member (102) including a generally tubular sidewall having an outer surface (115), an inner surface (113) defining a lumen configured to direct blood flow, a first end portion (106) and a second end portion (108), and a damping region (120) between the first and second end portions (106, 108). The inner and outer surfaces (113, 115) of the damping member (102) can be spaced apart by a distance that is greater at the damping region (120) than at either of the first or second end portions (106, 108).

Abstract: An automatic can crusher apparatus for crushing cans for recycling includes a housing having a ram aperture extending through to a housing inside. A ram has a pneumatic cylinder body, a ram arm extending through the ram aperture, and a ram head coupled to the ram arm. The ram moves the ram head between a load position and a crush position adjacent a housing right side. A can positioner is coupled to a housing left side within the housing inside to secure a can adjacent the ram head in the load position. A feeder chute is coupled to the housing top side to receive a plurality of cans through a chute top end and dispense each can through a chute bottom end onto the can positioner when the ram head is in the load position.

Abstract: A fluid-containing cap that fits onto corresponding tubing connectors comprised of a housing and rigid, non-compressible internal fluid reservoir. Fluid is retained within the cap by means of a high surface area internal structure providing sufficient surface tension to prevent fluid from exiting the reservoir until a corresponding tubing connector is inserted therein causing the fluid to disperse out of the cap reservoir and onto the inserted tubing connector.

Abstract: Techniques for authentication using a blockchain hash value as a moving factor. The techniques include retrieving, by an authenticating device and from a blockchain, a current hash value of the blockchain, where the authenticating device and an authenticator server share a secret key value and each have access to the blockchain. The techniques further including generating, by the authenticating device, a secure token based on the secret key value and the current hash value. The techniques further including transmitting the secure token to the authenticator server and receiving an indication of authentication from the authenticator server.

Abstract: A system is provided for training a machine learning model to detect malicious container files. The system may include at least one processor and at least one memory. The memory may include program code which when executed by the at least one processor provides operations including: processing a container file with a trained machine learning model, wherein the trained machine learning is trained to determine a classification for the container file indicative of whether the container file includes at least one file rendering the container file malicious; and providing, as an output by the trained machine learning model, an indication of whether the container file includes the at least one file rendering the container file malicious. Related methods and articles of manufacture, including computer program products, are also disclosed.

Abstract: Devices, systems, and methods for reducing stress on a blood vessel are disclosed herein. A damping device (100) configured in accordance with embodiments of the present technology can include an anchoring member (104) coupled to a flexible, compliant damping member (102) including a generally tubular sidewall having an outer surface (115), an inner surface (113) defining a lumen configured to direct blood flow, a first end portion (106) and a second end portion (108), and a damping region (120) between the first and second end portions (106, 108). The inner and outer surfaces (113, 115) of the damping member (102) can be spaced apart by a distance that is greater at the damping region (120) than at either of the first or second end portions (106, 108).

Abstract: An automatic can crusher apparatus for crushing cans for recycling includes a housing having a ram aperture extending through to a housing inside. A ram has a pneumatic cylinder body, a ram arm extending through the ram aperture, and a ram head coupled to the ram arm. The ram moves the ram head between a load position and a crush position adjacent a housing right side. A can positioner is coupled to a housing left side within the housing inside to secure a can adjacent the ram head in the load position. A feeder chute is coupled to the housing top side to receive a plurality of cans through a chute top end and dispense each can through a chute bottom end onto the can positioner when the ram head is in the load position.

Abstract: A system and method for assisting a user in assembling a culinary combination according to a recipe. The system comprises a scale and a computing device configured to communicate with the scale. The system displays information regarding ingredients of the recipe and displays a progress of assembling the culinary combination based on the information from the scale. In some embodiments, a bar graph is displayed with a bar proportional to the measured amount of an ingredient of the recipe compared to a target amount for the ingredient. In some embodiments, the system displays a build column of one or more recipe blocks, representing actions or ingredients of the recipe. An active recipe block is displayed with a portion of the recipe block displayed in a different manner in proportion to the measured amount of an ingredient of the recipe compared to a target amount for the ingredient.

Abstract: Systems and methods are disclosed for backing up a computer. The method includes choosing a time window to back up the computer; determining jobs that need to be synced during the time window and snapshots; determining an optimal set of snapshots that cover all jobs; altering job records in the database to point to one of the optimal snapshots; and deleting all snapshots not in the optimal set.