Abstract: A magnetic tape cartridge, a recording system, and a magnetic tape drive are configured to, for example, guard against tampering with a write once overwrite protection pointer which allows a rewritable magnetic tape to be treated as write once. In one embodiment, the magnetic tape cartridge comprises a magnetic tape and a cartridge memory. The magnetic tape is configured to provide at least one overwrite protection pointer, the overwrite protection pointer identifying data to be protected from being overwritten; and the cartridge memory is configured to provide the at least one overwrite protection pointer, the overwrite protection pointer identifying magnetic tape data to be protected from being overwritten.

Abstract: Provided is a method for detecting metastases of epithelial cancers, comprising detecting in non-primary tissue overexpression of a nucleic acid of KS1/4, or detecting in non-primary tissue overexpression of a combination of nucleic acids of KS1/4 and PIP, of nucleic acids of KS1/4 and mam, of nucleic acids of PIP and mam, of nucleic acids of KS1/4, PIP and mam, or of nucleic acids of KS1/4 and lunx, the overexpression of a nucleic acid of KS1/4, or the overexpression of a combination of nucleic acids of KS1/4 and PIP, of nucleic acids of KS1/4 and mam, of nucleic acids of PIP and mam, of nucleic acids of KS1/4, PIP and mam, or of nucleic acids of KS1/4 and lunx in non-primary tissue being correlated with metastases of epithelial cancers.

Abstract: A Job Monitor for providing printer recognition and management of a print job entity is described. The Job Monitor includes a repository of attributes and status associated with each print job that passes through the system. Interfaces to the Job Monitor provide the ability for components to process a job according to the unique requirements of the processing component, and report job attributes and processing status of the job to the Job Monitor for common access by other components. Each component has access to common variables and can present job attributes or status to its respective external interface according to the unique requirements dictated by the external interface. Additionally, internal job processing components interface with the Job Monitor to access and report current processing status. The common status repository provided by the Job Monitor is used by the Job Monitor and other components to control the sequence of processing within the printer.

Abstract: The present invention relates to an improved synthesis of pyrrole capping group precursors.

Abstract: It has been discovered that using n-butylmethyldimethoxysilane (BMDS) as an external electron donor for succinate-containing Ziegler-Natta catalysts can provide a catalyst system that may prepare polypropylene films with improved properties. The catalyst systems of the invention provide for controlled chain defects/defect distribution and thus a regulated microtacticity along with broadened molecular weight distribution.

Abstract: Method and system for inserting an implant, such as vaso-occlusive device, an embolic containment device, or a stent into a vascular space to a vascular site in a body utilizing a lumen-reducing catheter. The method and system can be used to treat aneurysm, tumors and other vascular malformations. A guide is inserted into the vascular space. First and second catheters are inserted into the vascular space along the guide. The first or delivery catheter defines a first cavity, and the second or lumen-reducing catheter defines a second, smaller cavity. The second catheter is inserted within the first catheter. In one embodiment, an implant is advanced together with the first and second catheters to a vascular site. In an alternative embodiment, after the first and second catheters are positioned, the guide and the second catheter are removed from the first cavity, and an implant is inserted through the first cavity.

Abstract: Compounds, pharmaceutical compositions, kits and methods are provided for use with DPP-IV and other S9 proteases that comprise a compound of the formula: wherein the substituents are as defined herein.

Abstract: Compounds, pharmaceutical compositions, kits and methods are provided for use with glucokinase that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.

Abstract: A method of treating a neurological disorder comprises introducing an electrical stimulation lead within a patient's head, locating the stimulation lead within the 4th ventricle of the patient's head, and placing the stimulation lead adjacent the fastigium nucleus of the patient's brain. The method may further comprise stimulating the fastigium nucleus with the stimulation lead to treat the neurological disorder, for example, by increasing the flow of blood within the patient's brain.

Abstract: Methods and devices for blocking orifices and occluding cavities within a patient are provided. The device in one variation comprises first and second tubular members attached to a collapsible sealing element. The device can be placed through an orifice and the collapsible sealing element can be collapsed to seal the orifice. An embolic may be introduced distal to the sealing element to occlude a cavity. The device may incorporate a locking mechanism which can be engaged to lock the sealing element into the collapsed position. The device may incorporate a valve to prevent flow through the tubular members, for example to prevent egress of the embolic from a cavity. The device can be detached to provide a permanent seal of the orifice, and can retain the embolic within the cavity. The device may be used in conjunction with a stent or other retention device to assist the sealing element in maintaining the seal.

Abstract: The present invention relates to an improved synthesis of pyrrole capping group precursors.

Abstract: Apparatus for treating abnormal mucosa in an alimentary tract are provided. The apparatus include an ablation structure configured to be removably coupled to an endoscope and a deflection mechanism adapted to move the ablation structure with respect to the endoscope and toward a tissue surface.

Abstract: A method of treating a neurological disorder in a patient is provided. The method comprises intravascularly delivering a stimulation lead within the head of the patient, and placing the stimulation lead adjacent brain tissue (e.g., cortical brain tissue or deep brain tissue), the stimulation of which will treat the neurological disorder. The stimulation lead can be placed into indirect contact with the brain tissue (e.g., through a blood vessel) or indirect contact with the brain tissue (e.g., when placed within the ventricular cavity or by being introduced through an exit point within a vessel wall). Optionally, the method comprises implanting a source of stimulation within the patient's body, and then electrically coupling the proximal end of the stimulation lead, which conveniently extends from the access point within the circulatory system, to the implanted stimulation source. Using the stimulation lead, the brain tissue can then be stimulated in order to treat the neurological disorder.

Abstract: It has been discovered that using n-butylmethyldimethoxysilane (BMDS) as an external electron donor for Ziegler-Natta catalysts can provide a catalyst system that may prepare polypropylene films with improved properties. The catalyst systems of the invention provide for controlled chain defects/defect distribution and thus a regulated microtacticity. Consequently, the curve of storage modulus (G?) v. temperature is shifted such that the film achieves the same storage modulus at a lower temperature enabling faster throughput of polypropylene film through a high-speed tenter.

Abstract: An ablation device and methods for use thereof including a support structure adapted to support an ablation structure within an alimentary tract of a patient are provided. The support structure includes a longitudinal support with a longitudinal axis and a rotational support. The rotational support is adapted to permit at least part of the ablation structure to rotate with respect to the longitudinal support's longitudinal axis.

Abstract: Compounds, pharmaceutical compositions, kits and methods are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.

Abstract: Methods of ablating tissue in an alimentary tract are provided. The methods include advancing an ablation structure into an alimentary tract while supporting the ablation structure with an endoscope. The methods further include a step of moving at least part of the ablation structure with respect to the endoscope and toward a tissue surface, before activating the ablation structure to ablate a tissue surface.

Abstract: The present invention is directed to systems for occluding an aneurysm having an aneurysmal neck and an aneurysmal inner wall. Generally, a device in accordance with the present invention includes a mesh-like structure that is integrally composed of a shape-memory alloy such as NiTi. The device is deployed within the aneurysm through the aneurysmal neck. The device is configured to be in a deployed state and an undeployed state, and is configured to transition from the undeployed state to the deployed state by exposure to a higher temperature and/or by being unconstrained. The device may function to retain finer vaso-occlusive devices such as vaso-occlusive coils and/or embolic liquids. Furthermore, the device itself may function as a vaso-occlusive device.

Abstract: The present invention provides a portable illumination apparatus that is quickly installed into an existing cupboard or cabinet. The portable illumination apparatus runs on battery power and typically includes incandescent lamps, or LED lamps. An automatic on/off switching unit is responsive to the opening and closing of the cabinet door. In the preferred embodiment, the switching unit includes a protruding member which extends to the cabinet door. When the cabinet door is closed it rotates or depresses the protruding member, which in turn opens the switching unit contacts. When the cabinet door opens, a resilient member within the switching unit forces the contacts closed, thus providing battery power to the lamps, which then become illuminated.

Abstract: An authentication management platform that enables authentication systems from various vendors to be integrated into a single service offering. The disclosed arrangement can support multiple, distinct customers and multiple primary authentication servers on a single platform. The management platform provides access only to users that enter a valid passcode comprising both: (1) a personal identification number (PIN) and (2) the current code generated by a security token card assigned to that user. The authentication management platform may be configured to be controlled and maintained by the subscriber to the system, or may be serviced/maintained by a third party service provider.