Abstract: Described herein are techniques to enable a mobile device to perform multi-source estimation of an altitude for a location. A baseline altitude may be determined at ground level for a location and used to calibrate a barometric pressure sensor on the mobile device. The calibrated barometric pressure sensor can then estimate changes in altitude relative to ground level based on detected pressure differentials, allowing a relative altitude to ground to be determined. Baseline calibration for the barometric sensor calibration can be performed to determine an ambient ground-level barometric pressure.

Abstract: Methods, systems, and computer program products are provided for embedding learning to provide uniformity and orthogonality of embeddings. A method may include receiving a dataset that includes a plurality of data points including a first plurality of data points having a first classification and a second plurality of data points having a second classification, generating a first normalized class mean vector of the first plurality of data instances having the first classification, generating a second normalized class mean vector of the second plurality of data instances having the second classification, performing a class rectification operation on the first plurality of data instances having the first classification and the second plurality of data instances having a second classification, and generating embeddings of the dataset based on original embedding space projections of the dataset.

Abstract: A wireless transmit/receive unit (WTRU) may send a discovery request to a first edge enabler server (EES) instance to obtain edge application server (EAS) information. The WTRU may receive a discovery response from the first EES instance. The discovery response may indicate a list of EAS information and/or registrar EES information for one or more EAS instances in the list of EAS information. The WTRU may select an EAS instance based on one or more of the list of EAS information or the registrar EES information for the one or more EAS instances. A second EES instance of the plurality of EES instances may be the registrar EES of the selected EAS instance.

Abstract: The present invention relates to bifunctional compounds, which find utility to degrade and (inhibit) TBK1. In particular, the present invention is directed to compounds, which contain on one end an E3 ubiquitin ligase binding moiety which binds to an E3 ubiquitin ligase and on the other end a moiety which binds TBK1 such that TBK1 is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of TBK1. The present invention exhibits a broad range of pharmacological activities associated with compounds according to the present invention, consistent with the degradation/inhibition of TBK1.

Abstract: Triazabicylodecene can effectively n-dope a variety of organic semiconductors, including PCBM, thus increasing in-plane conductivities. We synthesized a series of TBD-based n-dopants via an N-alkylation reaction and studied the effect of various alkyl chains on the physical and device properties of the dopants. Combining two TBD moieties on a long alky chain gave a solid dopant, 2TBD-C10, with high thermal stability above 250° C. PCBM films doped by 2TBD-C10 were the most tolerant to thermal annealing and reached in-plane conductivities of 6.5×10?2 S/cm. Furthermore, incorporating 2TBD-C10 doped PCBM as the electron transport layer (ETL) in methylammonium lead triiodide (MAPbI3) based photovoltaics led to a 23% increase in performance, from 11.8% to 14.5% PCE.

Abstract: Methods, systems, and computer program products for generating, from an input character sequence, an output sequence of audio data representing the input character sequence. The output sequence of audio data includes a respective audio output sample for each of a number of time steps. One example method includes, for each of the time steps: generating a mel-frequency spectrogram for the time step by processing a representation of a respective portion of the input character sequence using a decoder neural network; generating a probability distribution over a plurality of possible audio output samples for the time step by processing the mel-frequency spectrogram for the time step using a vocoder neural network; and selecting the audio output sample for the time step from the possible audio output samples in accordance with the probability distribution.

Abstract: An indexed sequence of bits in a buffer is allocated for tracking a battery charging state. The indexed sequence of bits has a first number of bits. A battery voltage of a rechargeable battery is sampled at a sampling rate. For each sampled battery voltage, the battery voltage is compared with a voltage threshold. A next bit position in the indexed sequence of bits is identified. In accordance with a determination that a comparison result is true, a predefined first value is added to the next bit position. A second number of bits that are filled with the predefined first value is determined. A ratio between the second number and the first number is also determined. In accordance with a determination that the ratio exceeds a threshold step-down ratio, a battery charge voltage is stepped down. The rechargeable battery is charged to a step-down voltage.

Abstract: An opto-electronic device includes: a first electrode; an organic layer disposed over the first electrode; a nucleation promoting coating disposed over the organic layer; a nucleation inhibiting coating covering a first region of the opto-electronic device; and a conductive coating covering a second region of the opto-electronic device.

Abstract: An opto-electronic device includes: (1) a substrate including a first region and a second region; and (2) a conductive coating covering the second region of the substrate. The first region of the substrate is exposed from the conductive coating, and an edge the conductive coating adjacent to the first region of the substrate has a contact angle that is greater than about 20 degrees.

Abstract: A method performed by a server computer is disclosed. The method comprises generating a binary compositional code matrix from an input matrix. The binary compositional code matrix is then converted into an integer code matrix. Each row of the integer code matrix is input into a decoder, including plurality of codebooks, to output a summed vector for each row. The method then includes inputting a derivative of each summed vector into a downstream machine learning model to output a prediction.

Abstract: Compositions and methods for the treatment of peripheral artery disease and cardiopulmonary diseases or disorders are provided. In accordance with the instant invention, methods of inhibiting, treating, and/or preventing peripheral artery disease or symptoms associated therewith are provided. In a particular embodiment, the methods inhibit, treat, and/or prevent claudication associated with peripheral artery disease.

Abstract: Provided herein are aza-tetracyclic oxazepinyl compounds useful in the treatment of cancers.

Abstract: Disclosed herein are compositions and methods for decrosslinking formaldehyde cross-linked biological samples such as formalin-fixed, paraffin-embedded (FFPE) tissue samples.

Abstract: Described herein are compositions and methods related to antigen binding proteins that bind to human ST2, including antibodies. In particular embodiments, the disclosure provides fully human anti-ST2 antibodies and deriviatives and variants thereof. Further provided are nucleic acids encoding such antibodies and antibody fragments, variants, and derivatives. Also, provided are methods of making and using such antibodies including methods of treating and preventing autoimmune and inflammatory disorders.

Abstract: Cinnoline compounds of formula (I): variations thereof, and their use as inhibitors of HPK1 (hematopoietic kinase 1) are described. The compounds are useful in treating HPK1-dependent disorders and enhancing an immune response. Also described are methods of inhibiting HPK1, methods of treating HPK1-dependent disorders, methods for enhancing an immune response, and methods for preparing the cinnoline compounds.

Abstract: A data processing system implements obtaining presentation content for a presentation, the presentation content including a set of slides and a transcript. The system further implements obtaining presentation style information for the presentation from a presentation datastore, generating a prompt for a LLM that includes the transcript and the presentation style information to cause the first LLM to generate an augmented transcript by rewriting the textual cues of the first transcript into a conversational style associated with the presentation style identified in the presentation style information; generating audiovisual content by generating speech for a virtual presenter and generating audiovisual content synchronizing an animation of the virtual presenter with the first audio content, and sending the audiovisual content to the computing devices of users who are in an audience of the presentation.

Abstract: The disclosure provides at least one entity chosen from compounds of Formula I, a tautomer thereof, a deuterated derivative of that compound or tautomer, and a pharmaceutically acceptable salt of any of the foregoing, compositions comprising the same, and methods of using the same, including uses in treating APOL1-mediated diseases, including pancreatic cancer, focal segmental glomerulosclerosis (FSGS), and/or non-diabetic kidney disease (NDKD).

Abstract: The present invention provides a method for detecting and adjusting failed back-drills in PCBs in the process of fabricating a PCB so that the failed back-drill can be screened out or repaired. This is accomplished, by after detecting poor back drills in a PCB, measuring the actual thickness of each PCB board. Next, the measured actual thickness of each PCB board is compared with .the theoretical thickness of each PCB board. The back drill depth for each area of the PCB board is then adjusted for its theoretical thickness and percent variation from the measured thickness to adjust the poor back drill.

Abstract: The present invention provides for compounds of formula (I) wherein R1, R2, R3, R4, R6, X1, and X2 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising compounds of formula (I).

Abstract: An atomizing core, an atomizer, an electronic cigarette, and an assembly method are provided. The atomizing core is used for atomizing an atomizing substrate to form an aerosol, and includes: an atomizing core housing defining an airflow inlet, an airflow outlet, an accommodating space between the airflow inlet and the airflow outlet, and at least one atomizing substrate inlet in communication with the accommodating space; an atomizing seat arranged in the accommodating space and defining an atomizing channel for being in communication with the airflow inlet and the airflow outlet, and at least one opening for communicating the at least one atomizing substrate inlet with the atomizing channel; and at least one heating sheet arranged in the atomizing channel and at least partially opposite one or more of the at least one opening respectively. Embodiments of the present disclosure can increase the degree of integration of the atomizing core, so as to increase production efficiency and product stability.