Abstract: Certain embodiments of the disclosure are directed to variant filamentous fungal cells, compositions thereof and methods thereof for increased production of one or more proteins of interest. More particularly, in certain embodiments, the disclosure is directed to variant filamentous fungal (host) cells derived from parental filamentous fungal cells, wherein the variant host cells comprise a genetic modification which enables the expression/production of a protein of interest (POI) in the absence of inducing substrate. In certain embodiments, a variant fungal host cell of the disclosure comprises a genetic modification which increases the expression of a variant activator of cellulase expression 3 (ace3) gene encoding an Ace3 protein referred to herein as Ace3-L.

Abstract: The present disclosure provides apparatuses, systems, and methods for performing particle analysis through flow cytometry at comparatively high event rates and for gathering high resolution images of particles.

Abstract: A system for connecting a fiber optic connector to a fiber optic adapter includes various alternative improvements, including improvements to the shutter, the alignment device, and the adapter in general.

Abstract: A payment processing system is configured to support purchase transactions generated by merchant point-of-sale (POS) devices. Information regarding the purchase transactions is archived and periodically analyzed using machine learning to create a predictive model relating transaction attributes to bank interchange fees. The predictive model is then used to estimate interchange fees that are later passed on to merchants. This allows more accurate settlement with merchants in situations where reports regarding actual interchange fees are not yet available.

Abstract: The present disclosure provides apparatuses, systems, and methods for performing particle analysis through flow cytometry at comparatively high event rates and for gathering high resolution images of particles.

Abstract: Audio content coded for a reference speaker configuration is downmixed to downmix audio content coded for a specific speaker configuration. One or more gain adjustments are performed on individual portions of the downmix audio content coded for the specific speaker configuration. Loudness measurements are then performed on the individual portions of the downmix audio content. An audio signal that comprises the audio content coded for the reference speaker configuration and downmix loudness metadata is generated. The downmix loudness metadata is created based at least in part on the loudness measurements on the individual portions of the downmix audio content.

Abstract: A method for trusted notifications comprises: receiving, at a first host having at least one trusted server, a request message from a sender computing device, the request message comprising a request identifier and instructions to: update, at a second host, a recipient account associated with a recipient computing device, and to make a corresponding update at the first host to a sender account associated with the sender computing device. The method further comprises authorizing, at the first host, the request message; updating the sender account; generating a secure message at the at least one trusted server, the secure message comprising the request identifier and an indication from the at least one trusted server that the update completed; and sending the secure message from the first host to the sender computing device. The secure message can be received at the sender computer device and conveyed to the recipient computing device.

Abstract: A heat pump water heater appliance includes an electronic mixing valve. The electronic mixing valve is positioned within a casing of the heat pump water heater appliance. A mixed water conduit and a heated water conduit of the electronic mixing valve may be positioned coaxially with each other, and a cold water conduit of the electronic mixing valve may be oriented such that the cold water conduit extends orthogonal to the heated water conduit and the mixed water conduit. A plunger is positioned within the valve body at the mixing chamber of the valve body. A motor is coupled to the plunger, the motor being operable to adjust a position of a head of the plunger within the valve body.

Abstract: A system for connecting a fiber optic connector to a fiber optic adapter includes various alternative improvements, including improvements to the shutter, the alignment device, and the adapter in general.

Abstract: The present disclosure provides devices, systems and methods for concentrating particles after application of a field and flipping the direction of the particles. The field applied to the particles can be an acoustic field. The particles can be flipped from a first flow stream at a higher speed into a second flow stream at a lower speed to aid in concentrating the particles, including concentration within an analysis region.

Abstract: Hot water heater systems and methods for monitoring electronic mixing valves of hot water heater systems are provided. An electronic mixing valve provides a flow of water in a mixed output line. A method includes determining whether an output flow event is occurring, determining a first temperature value for water in the mixed output line when the output flow event is occurring, comparing the first temperature value to a setpoint temperature value to obtain a first temperature error value when the output flow event is occurring, and generating a failure signal when the first temperature error value is outside of a predetermined error range and the output flow event is occurring.

Abstract: Described are compositions and methods relating variant filamentous fungi having altered growth characteristics. Such variants are well-suited for growth in submerged cultures, e.g., for the large-scale production of enzymes and other proteins for commercial applications.

Abstract: A heat shield for a turbocharger has a disc-like configuration. The heat shield includes an outer radial portion, an outer wall, a connecting wall, and an inner wall. The outer radial portion is disposed circumferentially around an axis of the heat shield. The outer wall extends from the outer radial portion in a first axial direction. The connecting wall extends radially inward substantially perpendicularly from the outer wall. The inner wall extends substantially perpendicularly from the connecting wall in a second axial direction opposite the first axial direction.

Abstract: A gas fueled water heater appliance having a temperature control switch is provided herein. The gas fueled water heater appliance may include a tank for storage of water for heating, a chamber wall, a gas burner, a valve, the temperature control switch, and a conductive probe. The chamber wall may define a combustion chamber. The gas burner may be positioned adjacent to the tank and within the combustion chamber to heat the water in the tank. The valve may control a flow of gaseous fuel to the gas burner. The temperature control switch may be in operable communication with the valve. The conductive probe may extend through the chamber wall from a first end positioned on the temperature control switch to a second end positioned within the combustion chamber.

Abstract: A method of generating an unpredictable number in a computing device is provided. The method comprises the computing device performing the following programmed steps: obtaining a plurality of data elements; performing a first one way function on an internal value P and the plurality of data elements to update the value P; and performing a second one way function on the value P to obtain the unpredictable number. A computing device adapted to perform this method is also described.

Abstract: The present invention comprises methods and systems that use acoustic radiation pressure.

Abstract: A sampling system is provided. The sampling system includes a housing. Mounted to the housing is a Hall effect sensor. A probe configured to contact a sample is inserted into the housing. The probe includes an elongated portion and a restorative spring inserted onto the elongated portion of the probe. The restorative spring provides sufficient restorative force to return the probe to a relaxed position. The Hall effect sensor is configured to sense a field strength generated by the proximity of the restorative spring of the probe in the extended position.

Abstract: A gas fueled water heater appliance having a flame arrestor is provided herein. The gas fueled water heater appliance may include a tank for storage of water for heater, a chamber wall, a gas burner, and the flame arrestor. The gas burner may be positioned adjacent to the tank and within a combustion chamber. The flame arrestor may be positioned beneath the gas burner. The flame arrestor may include a bottom plate and a top plate. The bottom plate may define a non-permeable region and a perforated region. The perforated region may include a plurality of apertures extending through the top plate. The top plate may be positioned above the bottom plate and may define a non-permeable region and a perforated region. The perforated region may include a plurality of apertures extending through the top plate.

Abstract: An intracranial, light-emitting implant for providing therapy to a patient having Alzheimer's Disease.