Abstract: A key arrangement includes an activation element, a switch, a mechanical counterforce generating device, and a permanent magnet arrangement. The switch has at least a first state and a second state. The activation element has a basic state and an activation state and is configured to, in case of activation by a user, permit a movement from the basic state into the activation state, and in case of the movement into the activation state to permit a change in the state of the switch. The mechanical counterforce generating device is configured to generate, in case of an activation of the activation element, a first counterforce at least in certain areas. The permanent magnet arrangement is configured to generate, in case of activation of the activation element, a second counterforce at least in certain areas.

Abstract: A key arrangement includes an activation element, a switch, a mechanical counterforce generating device, and a permanent magnet arrangement. The switch has at least a first state and a second state. The activation element has a basic state and an activation state and is configured to, in case of activation by a user, permit a movement from the basic state into the activation state, and in case of the movement into the activation state to permit a change in the state of the switch. The mechanical counterforce generating device is configured to generate, in case of an activation of the activation element, a first counterforce at least in certain areas. The permanent magnet arrangement is configured to generate, in case of activation of the activation element, a second counterforce at least in certain areas.

Abstract: A flange plate for a manifold of an exhaust-gas system for internal combustion engines, which flange plate can be fixed via at least one holding device to an exhaust-gas outlet connecting piece of the internal combustion engine by a first outer layer, formed as a mounting layer, which can be placed at least partially directly or indirectly against the exhaust-gas outlet connecting piece via a seal, and the flange plate can be applied to the holding device by a second outer layer, formed as a holding layer, in order to generate a holding force F, acting at a right angle to the mounting layer, for sealingly placing the mounting layer against the exhaust-gas outlet connecting piece, and the flange plate having at least a first intermediate layer which is arranged, relative to the holding force F, between the mounting layer and the holding layer.

Abstract: A housing for fluidically connecting an exhaust gas line to an exhaust gas heat exchanger, wherein the main flow channel of the housing extends in the direction of a central axis (X), from an inlet opening to an outlet opening, with an average flow cross section (SQ). In the main flow channel, at least one opening is provided in the housing for a valve shaft, and on the housing, at least one bypass opening formed by a connecting piece is provided between the inlet opening and the outlet opening. The housing is formed by a maximum of two deep-drawn sub-shells made of sheet metal, wherein the connecting piece is formed circumferentially around the bypass axis (Y) for connecting an exhaust gas heat exchanger via the upper shell and/or via the lower shell.

Abstract: A method for encasing a body of an exhaust gas system with a housing which is wound around the body. Using a winding method, the body is placed in a loop formed by a belt-shaped conveyor element that can be driven in a conveyor device, wherein the conveyor element is seated against the outer casing face at a wrapping angle u of at least 270 degrees. Starting with a first edge, the metal strip is then introduced in a conveyor device between the body and the conveyor element, is drawn into the gap between the body and the conveyor element and is bent around the body until the body is encased at least twice by the metal strip.

Abstract: A housing for fluidically connecting an exhaust gas line to an exhaust gas heat exchanger, wherein the main flow channel of the housing extends in the direction of a central axis (X), from an inlet opening to an outlet opening, with an average flow cross section (SQ). In the main flow channel, at least one opening is provided in the housing for a valve shaft, and on the housing, at least one bypass opening formed by a connecting piece is provided between the inlet opening and the outlet opening. The housing is formed by a maximum of two deep-drawn sub-shells made of sheet metal, wherein the connecting piece is formed circumferentially around the bypass axis (Y) for connecting an exhaust gas heat exchanger via the upper shell and/or via the lower shell.

Abstract: A flange plate for a manifold of an exhaust-gas system for internal combustion engines, which flange plate can be fixed via at least one holding device to an exhaust-gas outlet connecting piece of the internal combustion engine by a first outer layer, formed as a mounting layer, which can be placed at least partially directly or indirectly against the exhaust-gas outlet connecting piece via a seal, and the flange plate can be applied to the holding device by a second outer layer, formed as a holding layer, in order to generate a holding force F, acting at a right angle to the mounting layer, for sealingly placing the mounting layer against the exhaust-gas outlet connecting piece, and the flange plate having at least a first intermediate layer which is arranged, relative to the holding force F, between the mounting layer and the holding layer.

Abstract: A method for encasing a body of an exhaust gas system with a housing which is wound around the body. Using a winding method, the body is placed in a loop formed by a belt-shaped conveyor element that can be driven in a conveyor device, wherein the conveyor element is seated against the outer casing face at a wrapping angle u of at least 270 degrees. Starting with a first edge, the metal strip is then introduced in a conveyor device between the body and the conveyor element, is drawn into the gap between the body and the conveyor element and is bent around the body until the body is encased at least twice by the metal strip.

Abstract: A method for encasing a body of an exhaust gas system with a housing which is wound around the body. Using a winding method, the body is placed in a loop formed by a belt-shaped conveyor element that can be driven in a conveyor device, wherein the conveyor element is seated against the outer casing face at a wrapping angle u of at least 270 degrees. Starting with a first edge, the metal strip is then introduced in a conveyor device between the body and the conveyor element, is drawn into the gap between the body and the conveyor element and is bent around the body until the body is encased at least twice by the metal strip.

Abstract: A multipart gas pipe flange for connecting to a counter-flange of an internal combustion engine, having at least one flange plate designed as an outer flange, and having a flange inner part that can be received in said flange plate and is used for attaching a gas pipe which is connected downstream of the inner part in the flow direction and which is fluidically connected. The flange plate has at least one recess for the flange inner part, said recess having at least one inner surface and an inner diameter Di, and a mounting surface which can be placed at least indirectly on the counter-flange. The flange inner part has an outer surface which corresponds to the inner surface and which has an outer diameter Da.

Abstract: The present invention relates to speaker enclosures utilizing the golden ratio geometrically throughout the design to reduce reflections, resonance and phase shifting, and to improve the transient response. Enclosures can be box-shaped, trapezoidal, suspended or otherwise configured. The enclosure has a driver wall, a baffle and a rear wall. The driver wall and baffle define a front chamber, and the baffle and rear wall define a rear chamber. The volumetric ratio between the rear chamber and front chamber can be approximately 0.6. The rear chamber also can have braces or dividers that segment the chamber into a central portion and two side portions. The volumetric ratio between the side portions and the central portion can be approximately 0.6. Ports of various configurations are provided. Braces can be used in conjunction with the ports to diffuse the incoming air. The baffle can have a plurality of radiused holes there through.

Abstract: A method for encasing a body of an exhaust gas system with a housing which is wound around the body. Using a winding method, the body is placed in a loop formed by a belt-shaped conveyor element that can be driven in a conveyor device, wherein the conveyor element is seated against the outer casing face at a wrapping angle u of at least 270 degrees. Starting with a first edge, the metal strip is then introduced in a conveyor device between the body and the conveyor element, is drawn into the gap between the body and the conveyor element and is bent around the body until the body is encased at least twice by the metal strip.

Abstract: The present invention relates to speaker enclosures utilizing the golden ratio geometrically throughout the design to reduce reflections, resonance and phase shifting, and to improve the transient response. Enclosures can be box-shaped, trapezoidal, suspended or otherwise configured. The enclosure has a driver wall, a baffle and a rear wall. The driver wall and baffle define a front chamber, and the baffle and rear wall define a rear chamber. The volumetric ratio between the rear chamber and front chamber can be approximately 0.6. The rear chamber also can have braces or dividers that segment the chamber into a central portion and two side portions. The volumetric ratio between the side portions and the central portion can be approximately 0.6. Ports of various configurations are provided. Braces can be used in conjunction with the ports to diffuse the incoming air. The baffle can have a plurality of radiused holes there through.

Abstract: Mono-acylated o-phenylendiamines derivatives of formula A: which are useful for the treatment of diseases mediated by the inhibition of histone deacetylase, such as cancer.

Abstract: The invention comprises a nucleic acid molecule with the sequence SEQ ID NO:5 and the complementary sequence, and its use in diagnosis and therapy. This nucleic acid molecule (IIP-10) is a gene which encodes an IGF-1 receptor binding polypeptide.

Abstract: In a method for generating a color match between a target object having a plurality of different target color values and a source object, a target color space with target color locations to be correlated with target color values is generated for the target object. For the source object, a source color space having a plurality of source color locations is generated, wherein the source color locations are correlated with a source color value, respectively. For each target color location a position in the vicinity of a similar source color location is determined within the source color space. The spacing of this position from the similar source color location is determined, and, based on the spacing, the source color value correlated with the similar source color location is changed.

Abstract: The invention relates generally to a method for the detection of the proliferation of a tumor cell and more specifically wherein said method comprises nucleic acids (SEQ ID NO:1) encoding IIP-1.

Abstract: The invention comprises a nucleic acid molecule with the sequence SEQ ID NO:5 and the complementary sequence, and its use in diagnosis and therapy. This nucleic acid molecule (IIP-10) is a gene which encodes an IGF-1 receptor binding polypeptide.

Abstract: Mono-acylated o-phenylendiamines derivatives of formula I wherein X and R are as described herein, have been found useful for the treatment of diseases mediated by the inhibition of histone deacetylase, such as cancer.

Abstract: The invention comprises a method of screening compound(s) that inhibit the interaction between IGF-1R and IIP-10.