Patents by Inventor Michael Wiedmann

Michael Wiedmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240122777
    Abstract: Systems are provided for an imaging system isolation enclosure for use with a medical imaging system includes a pathogen impermeable enclosure for use with one or more of radiation imaging systems and magnetic resonance imaging systems, the pathogen impermeable enclosure is configured to provide a barrier between the imaging system and at least one of a patient user and an imaging room, and an air filtration system including an inlet to supply a cooling air flow to an interior of the imaging system isolation enclosure and an outlet to output exhaust air from an interior of the imaging system isolation enclosure.
    Type: Application
    Filed: October 17, 2022
    Publication date: April 18, 2024
    Inventors: Paul Francis FitzGerald, Uwe Wiedmann, Ross Christopher Stalter, Stephen Lorenco Araujo, Michael James Rishel, Chad Allan Smith
  • Publication number: 20230358748
    Abstract: Herein is reported a method for determining the presence of hydrolase activity in a sample by incubating the sample in a buffered solution, which comprises an artificial hydrolase substrate that comprises an ester bond covalently linking an alcohol residue, which is conjugated to a label for removal, and a carboxylic acid residue, which is conjugated to a capture and detection label, as well as bovine serum albumin, and thereafter determining or quantifying, respectively, the released carboxylic acid in the free alcohol depleted incubation mixture.
    Type: Application
    Filed: December 16, 2022
    Publication date: November 9, 2023
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Franziska EDELMANN, Roberto FALKENSTEIN, Tobias GRAF, Sanjay GUPTA, Lars HILLRINGHAUS, Tarik Ali KHAN, Michael LEISS, Thomas MEIER, Michael WIEDMANN
  • Publication number: 20220169675
    Abstract: The current invention reports a method for purifying an antibody by reducing the content of a host cell protein. The method employs a wash step with a low conductivity aqueous solution in an affinity chromatography.
    Type: Application
    Filed: May 24, 2021
    Publication date: June 2, 2022
    Applicants: Genentech, Inc., Hoffmann-La Roche Inc.
    Inventors: Paul MCDONALD, Richard ST. JOHN, Marc Wong, Roberto FALKENSTEIN, Wolfgang KOEHNLEIN, Klaus SCHWENDNER, Bernhard SPENSBERGER, Michael WIEDMANN, Frank ZETTL, Annika KLEINJANS, Carina KOPP, Benjamin TRAN, Ryan ERICKSON
  • Publication number: 20210397893
    Abstract: A method for providing training images including receiving information about objects which is at least valid at a specific recording time. The method includes receiving an image of an area imaged at the specific recording time. The method includes estimating respective positions of the objects at the specific recording time based on the information and selecting estimated positions of respective objects from the estimated respective positions which fulfill a predefined selection criterion. The method includes generating training images by separating the imaged area into first and second pluralities of image tiles. Each of the first plurality of image tiles differs from each of the second plurality of image tiles. Each of the first plurality of image tiles images (depicts) a respective one or several of the selected positions. The method includes providing the training images. Further, a training image product and a device for providing training images are provided.
    Type: Application
    Filed: October 30, 2019
    Publication date: December 23, 2021
    Inventors: Camilla MOHRDIECK, Michael WIEDMANN, Reiner ZIMMERMANN
  • Publication number: 20180186832
    Abstract: The current invention reports a method for purifying an antibody by reducing the content of a host cell protein. The method employs a wash step with a low conductivity aqueous solution in an affinity chromatography.
    Type: Application
    Filed: February 20, 2018
    Publication date: July 5, 2018
    Applicants: Genentech, Inc., Hoffmann-La Roche Inc
    Inventors: Paul MCDONALD, Richard ST. JOHN, Marc WONG, Roberto FALKENSTEIN, Wolfgang KOEHNLEIN, Klaus SCHWENDNER, Bernhard SPENSBERGER, Michael WIEDMANN, Frank ZETTL, Annika KLEINJANS, Carina KOPP, Benjamin TRAN, Ryan ERICKSON
  • Publication number: 20110048000
    Abstract: The invention relates to a turbine, in particular an exhaust gas power turbine for a turbo-compound system, comprising a drive shaft, which carries a turbine wheel on its first end or in the area of the first end, which is intended for positioning in an exhaust gas stream of an internal combustion engine or another medium stream containing thermal and/or pressure energy, in order to convert exhaust gas energy or energy of the medium stream into drive power, and which carries a gearwheel on its second end or in the area of the second end, which is designed for the purpose of being placed in a drive connection with the crankshaft of the internal combustion engine, the drive shaft being mounted, at least in the area of its second end adjacent to the gearwheel, using a floating bush in a housing, which forms an outer oil-filled bearing gap in relation to the housing and an inner oil-filled bearing gap in relation to the drive shaft and is relatively rotatable in relation to the housing and the drive shaft.
    Type: Application
    Filed: August 6, 2010
    Publication date: March 3, 2011
    Inventors: Markus Kley, Michael Wiedmann
  • Publication number: 20100136519
    Abstract: The invention concerns a process for the immunological determination of a specific antibody in a fluid sample. The process involves incubating the fluid sample in the presence of a solid phase with two antigens directed against the antibody whose presence is to be determined; the first antigen carries at least one marker group, while the second is either (a) bonded to the solid phase or (b) present in a form in which it can bond with the solid phase, and betrays the presence of the antibody being sought by showing the presence of the marker group in the solid phase and/or in the fluid phase. The proposed process is characterised by the fact that at least one of the two antigens has several epitopic regions which react with the antibody to be determined.
    Type: Application
    Filed: October 27, 2009
    Publication date: June 3, 2010
    Applicant: Roche Diagnostics GmbH
    Inventors: Ursula-Henrike Wienhues, Cornelia Kruse-Müller, Eva Höss, Elke Faatz, Beatus Ofenloch-Hähnle, Christoph Seidel, Michael Wiedmann
  • Patent number: 7629295
    Abstract: The invention concerns a method for the immunological determination of a specific antibody in a sample liquid in which the sample liquid is incubated in the presence of a solid phase with two antigens directed against the antibody to be determined of which the first antigen carries at least one marker group and the second antigen is (a) bound to the solid phase or (b) is present in a form capable of binding to the solid phase and the antibody to be determined is detected by determining the marker group in the solid phase or/and in the liquid phase characterized in that at least one of the two antigens contains several epitope regions which react with the antibody to be determined.
    Type: Grant
    Filed: July 7, 2003
    Date of Patent: December 8, 2009
    Assignee: Roche Diagnostics GmbH
    Inventors: Ursula-Henrike Wienhues, Cornelia Kruse-Müller, Eva Höss, Elke Faatz, Beatus Ofenloch-Hähnle, Christoph Seidel, Michael Wiedmann
  • Publication number: 20090098528
    Abstract: The present invention concerns a polypeptide which is composed of the amino acids 1207±10 to 1488±10 of a hepatitis C virus and of less than 20 foreign amino acids and the use of this polypeptide as an antigen in an immunological test.
    Type: Application
    Filed: October 11, 2007
    Publication date: April 16, 2009
    Inventors: Christoph Seidel, Ursula-Henrike Wienhues, Urban Schmitt, Manfred Motz, Michael Wiedmann, Barbara Upmeier, Erwin Soutscheck
  • Patent number: 7122302
    Abstract: The present invention concerns a polypeptide which is composed of the amino acids 1207±10 to 1488±10 of a hepatitis C virus and of less than 20 foreign amino acids and the use of this polypeptide as an antigen in an immunological test.
    Type: Grant
    Filed: June 29, 2001
    Date of Patent: October 17, 2006
    Assignee: Roche Diagnostic GmbH
    Inventors: Christoph Seidel, Ursula-Henrike Wienhues, Urban Schmitt, Manfred Motz, Michael Wiedmann, Barbara Upmeier, Erwin Soutschek
  • Patent number: 6937197
    Abstract: An antenna for a keyless entry radiofrequency system of a vehicle has an antenna cable, a conductor of which extends through an opening in the vehicle body with a free end outside said vehicle to prevent shielding of the free end by the vehicle body.
    Type: Grant
    Filed: February 10, 2004
    Date of Patent: August 30, 2005
    Assignee: Hirschmann Electronics GmbH & Co. KG
    Inventors: Michael Wiedmann, Markus Pfletschinger, Dirk Wendt
  • Publication number: 20050095584
    Abstract: The present invention concerns a polypeptide which is composed of the amino acids 1207±10 to 1488±10 of a hepatitis C virus and of less than 20 foreign amino acids and the use of this polypeptide as an antigen in an immunological test.
    Type: Application
    Filed: March 17, 2004
    Publication date: May 5, 2005
    Inventors: Christoph Seidel, Ursula-Henrike Wienhues, Urban Schmitt, Manfred Motz, Michael Wiedmann, Barbara Upmeier, Erwin Soutschek
  • Publication number: 20050074750
    Abstract: The invention concerns a method for the immunological determination of a specific antibody in a sample liquid in which the sample liquid is incubated in the presence of a solid phase with two antigens directed against the antibody to be determined of which the first antigen carries at least one marker group and the second antigen is (a) bound to the solid phase or (b) is present in a form capable of binding to the solid phase and the antibody to be determined is detected by determining the marker group in the solid phase or/and in the liquid phase characterized in that at least one of the two antigens contains several epitope regions which react with the antibody to be determined.
    Type: Application
    Filed: July 7, 2003
    Publication date: April 7, 2005
    Inventors: Ursula-Henrike Wienhues, Cornelia Kruse-Muller, Eva Hoss, Elke Faatz, Beatus Ofenloch-Hahnle, Christoph Seidel, Michael Wiedmann
  • Publication number: 20040174312
    Abstract: An antenna for a keyless entry radiofrequency system of a vehicle has an antenna cable, a conductor of which extends through an opening in the vehicle body with a free end outside said vehicle to prevent shielding of the free end by the vehicle body.
    Type: Application
    Filed: February 10, 2004
    Publication date: September 9, 2004
    Applicant: Hirschmann Electronics GmbH & Co. KG
    Inventors: Michael Wiedmann, Markus Pfletschinger, Dirk Wendt
  • Patent number: 6613530
    Abstract: The invention concerns a method for the immunological determination of a specific antibody in a sample liquid in which the sample liquid is incubated in the presence of a solid phase with two antigens directed against the antibody to be determined of which the first antigen carries at least one marker group and the second antigen is (a) bound to the solid phase or (b) is present in a form capable of binding to the solid phase and the antibody to be determined is detected by determining the marker group in the solid phase or/and in the liquid phase characterized in that at least one of the two antigens contains several epitope regions which react with the antibody to be determined.
    Type: Grant
    Filed: January 24, 1997
    Date of Patent: September 2, 2003
    Assignee: Roche Diagnostics GmbH
    Inventors: Ursula-Henrike Wienhues, Cornelia Kruse-Müller, Eva Höss, Elke Faatz, Beatus Ofenloch-Hähnle, Christoph Seidel, Michael Wiedmann
  • Publication number: 20030129582
    Abstract: The present invention concerns a polypeptide which is composed of the amino acids 1207±10 to 1488±10 of a hepatitis C virus and of less than 20 foreign amino acids and the use of this polypeptide as an antigen in an immunological test.
    Type: Application
    Filed: June 29, 2001
    Publication date: July 10, 2003
    Inventors: Christoph Seidel, Ursula-Henrike Wienhues, Urban Schmitt, Manfred Motz, Michael Wiedmann, Barbara Upmeier, Erwin Soutschek
  • Patent number: 6306579
    Abstract: The present invention concerns a polypeptide which is composed of the amino acids 1207±10 to 1488±10 of a hepatitis C virus and of less than 20 foreign amino acids and the use of this polypeptide as an antigen in an immunological test.
    Type: Grant
    Filed: July 15, 1997
    Date of Patent: October 23, 2001
    Assignee: Roche Diagnostics GmbH
    Inventors: Christoph Seidel, Ursula-Henrike Wienhues, Urban Schmitt, Manfred Motz, Michael Wiedmann, Barbara Upmeier, Erwin Soutschek
  • Patent number: 6270960
    Abstract: The present invention concerns a polypeptide which is composed of the amino acids 1207±10 to 1488±10 of a hepatitis C virus and of less than 20 foreign amino acids and the use of this polypeptide as an antigen in an immunological test.
    Type: Grant
    Filed: June 12, 2000
    Date of Patent: August 7, 2001
    Assignee: Roche Diagnostics GmbH
    Inventors: Christoph Seidel, Ursula-Henrike Wienhues, Urban Schmitt, Manfred Motz, Michael Wiedmann, Barbara Upmeier, Erwin Soutschek
  • Patent number: 6096319
    Abstract: The present invention concerns a polypeptide which is composed of the amino acids 1207.+-.10 to 1488.+-.10 of a hepatitis C virus and of less than 20 foreign amino acids and the use of this polypeptide as an antigen in an immunological test.
    Type: Grant
    Filed: August 7, 1995
    Date of Patent: August 1, 2000
    Assignee: Roche Diagnostics GmbH
    Inventors: Christoph Seidel, Ursula-Henrike Wienhues, Urban Schmitt, Manfred Motz, Michael Wiedmann, Barbara Upmeier, Erwin Soutschek
  • Patent number: 5952185
    Abstract: The invention addresses new photo-activatable biotin derivatives having the formula I ##STR1## wherein R=?(CH.sub.2).sub.n --O.sub.m !.sub.q --?(CH.sub.2).sub.r --O.sub.s !.sub.t --(CH.sub.2).sub.pwith n,r=2,3; m,s=0,1; q+t=1-4; p=1-4,wherein the sum of all CH.sub.2 groups does not exceed 10and wherein R1 as a single or multiple substituent is hydrogen, C.sub.1 -C.sub.5 alkyl, NH.sub.2, COOH, F, Cl, or Br.and their preparation, their use to inactivate streptavidin, the use of the inactivated streptavidin to reduce interference in immunoassays.
    Type: Grant
    Filed: October 27, 1997
    Date of Patent: September 14, 1999
    Assignee: Boehringer Mannheim GmbH
    Inventors: Erasmus Huber, Michael Wiedmann, Frederic Donie