Patents by Inventor Michael Wilken
Michael Wilken has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12649706Abstract: Provided is a process for producing pure methanol from carbon dioxide-rich synthesis gas, the process including the following steps: at least partially reacting the carbon dioxide rich synthesis gas in a methanol synthesis unit, discharging a liquid crude methanol stream from the methanol synthesis unit, introducing the liquid crude methanol stream into a flash tank, discharging from the flash tank a liquid depressurized crude methanol stream as a bottoms product and a gaseous overhead product stream having synthesis gas components, introducing the liquid depressurized crude methanol stream into a distillation apparatus having of a single distillation column, separating the crude methanol stream in the distillation column, discharging an overhead product stream via an overhead product outlet, discharging a bottoms product stream via the bottoms product outlet, and discharging a pure methanol product stream via a first side draw.Type: GrantFiled: May 3, 2023Date of Patent: June 9, 2026Assignee: L'Air Liquide, Societe Anonyme Pour l'Etude et l'Exploitation des Procedes Georges ClaudeInventors: Timm Schuhmann, Tobias Oelmann, Michael Wilken
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Publication number: 20240208888Abstract: The invention relates to a process and to a plant for producing methanol from a synthesis gas having a hydrogen deficit. A fresh gas stream from a reformer unit which includes hydrogen and carbon oxides is combined with a hydrogen-containing stream from a hydrogen recovery stage. This affords a synthesis gas stream having a stoichiometry number SN, defined as SN=[n(H2)?n(CO2)]/[n(CO)+n(CO2)], of less than 2.0. The synthesis gas stream is combined with a residual gas stream and the synthesis gas stream and the residual gas stream are passed through a bed of a methanol synthesis catalyst at elevated pressure and elevated temperature to obtain a product stream having methanol and the residual gas stream, and the product stream is cooled to separate methanol from the residual gas stream.Type: ApplicationFiled: April 26, 2022Publication date: June 27, 2024Inventors: Veronika GRONEMANN, Michael WILKEN, Tobias OELMANN
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Publication number: 20230357111Abstract: Provided is a process for producing pure methanol from carbon dioxide-rich synthesis gas, the process including the following steps: at least partially reacting the carbon dioxide rich synthesis gas in a methanol synthesis unit, discharging a liquid crude methanol stream from the methanol synthesis unit, introducing the liquid crude methanol stream into a flash tank, discharging from the flash tank a liquid depressurized crude methanol stream as a bottoms product and a gaseous overhead product stream having synthesis gas components, introducing the liquid depressurized crude methanol stream into a distillation apparatus having of a single distillation column, separating the crude methanol stream in the distillation column, discharging an overhead product stream via an overhead product outlet, discharging a bottoms product stream via the bottoms product outlet, and discharging a pure methanol product stream via a first side draw.Type: ApplicationFiled: May 3, 2023Publication date: November 9, 2023Inventors: Timm SCHUHMANN, Tobias OELMANN, Michael WILKEN
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Patent number: 11578284Abstract: A process and a plant for purifying a crude gas stream containing sulfur components and hydrocarbons by gas scrubbing using a scrubbing medium which is selective for sulfur components in an absorption column. Heavy hydrocarbons and heavy mercaptans are removed from the crude gas in a lower section of the absorption column and the resulting, loaded scrubbing medium stream is fed separately from the other loaded scrubbing medium streams to a hot regeneration column. A vapor stream enriched in water, hydrocarbons and sulfur components is obtained as overhead product from the hot regeneration column and this stream is cooled to below its dew point and is separated in a gas-liquid-liquid phase separation apparatus. The resulting, organic liquid phase contains heavy hydrocarbons and heavy mercaptans and can thus be discharged from the process or the plant, as a result of which accumulation thereof in the scrubbing medium is prevented.Type: GrantFiled: June 29, 2021Date of Patent: February 14, 2023Assignee: L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges ClaudeInventors: Alfred Gubrinski, Dorit Rappold, Michael Wilken, Matthias Linicus
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Publication number: 20210403822Abstract: A process and a plant for purifying a crude gas stream containing sulfur components and hydrocarbons by gas scrubbing using a scrubbing medium which is selective for sulfur components in an absorption column. Heavy hydrocarbons and heavy mercaptans are removed from the crude gas in a lower section of the absorption column and the resulting, loaded scrubbing medium stream is fed separately from the other loaded scrubbing medium streams to a hot regeneration column. A vapor stream enriched in water, hydrocarbons and sulfur components is obtained as overhead product from the hot regeneration column and this stream is cooled to below its dew point and is separated in a gas-liquid-liquid phase separation apparatus. The resulting, organic liquid phase contains heavy hydrocarbons and heavy mercaptans and can thus be discharged from the process or the plant, as a result of which accumulation thereof in the scrubbing medium is prevented.Type: ApplicationFiled: June 29, 2021Publication date: December 30, 2021Inventors: Alfred Gubrinski, Dorit Rappold, Michael Wilken, Matthias Linicus
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Patent number: 9505684Abstract: A process and a plant for producing an olefin stream from a hydrocarbon mixture feed stream, wherein the olefin stream is depleted as regards its content of oxygen-containing organic compounds (oxygenates) as compared to the feed stream. The hydrocarbon mixture feed stream is charged to a separation column operated by a thermal separation process, for example to a distillation column, wherein a material stream enriched in oxygenates is withdrawn via a side outlet and removed from the process. The process according to the invention is particularly useful for processing the product streams obtained in the olefin synthesis by an OTO process.Type: GrantFiled: April 21, 2011Date of Patent: November 29, 2016Assignee: AIR LIQUIDE GLOBAL E&C SOLUTIONS GERMANY GMBHInventors: Hermann Bach, Thomas Renner, Martin Rothaemel, Michael Wilken
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Publication number: 20150344576Abstract: Compositions and methods for regulating an immune response in a subject are described. More particularly, described are human antibodies that regulate the activity of NK cells and allow a potentiation of NK cell cytotoxicity in mammalian subjects, and antibodies having antigen-binding properties similar to those of human monoclonal antibody 1-7F9 or 1-4F1. Described also are also fragments and derivatives of such antibodies, as well as pharmaceutical compositions comprising the same and their uses, particularly for use in therapy, to increase NK cell activity or cytotoxicity in subjects.Type: ApplicationFiled: August 18, 2015Publication date: December 3, 2015Inventors: Alessandro Moretta, Mariella Della Chiesa, Pascale Andre, Laurent Gauthier, Francois Romagne, Peter Andreas Nicolai Reumert Wagtmann, Ivan Svendsen, Stefan Zahn, Anders Svensson, Matthias Thorolfsson, Soren Berg Padkaer, Kristian Kjaergaard, Pieter Johannes Louis Spee, Michael Wilken
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Publication number: 20150191547Abstract: Compositions and methods for regulating an immune response in a subject are described. More particularly, described are human antibodies that regulate the activity of NK cells and allow a potentiation of NK cell cytotoxicity in mammalian subjects, and antibodies having antigen-binding properties similar to those of human monoclonal antibody 1-7F9 or 1-4F1. Described also are also fragments and derivatives of such antibodies, as well as pharmaceutical compositions comprising the same and their uses, particularly for use in therapy, to increase NK cell activity or cytotoxicity in subjects.Type: ApplicationFiled: March 16, 2015Publication date: July 9, 2015Inventors: Alessandro Moretta, Mariella Della Chiesa, Pascale Andre, Laurent Gauthier, Francois Romagne, Peter Andreas Nicolai Reumert Wagtmann, Ivan Svendsen, Stefan Zahn, Anders Svensson, Matthias Thorolfsson, Soren Berg Padkaer, Kristian Kjaergaard, Pieter Johannes Louis Spee, Michael Wilken
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Patent number: 8981065Abstract: Compositions and methods for regulating an immune response in a subject are described. More particularly, described are human antibodies that regulate the activity of NK cells and allow a potentiation of NK cell cytotoxicity in mammalian subjects, and antibodies having antigen-binding properties similar to those of human monoclonal antibody 1-7F9 or 1-4F1. Described also are also fragments and derivatives of such antibodies, as well as pharmaceutical compositions comprising the same and their uses, particularly for use in therapy, to increase NK cell activity or cytotoxicity in subjects.Type: GrantFiled: July 8, 2013Date of Patent: March 17, 2015Assignees: Novo Nordisk A/S—Novo Alle, Innate Pharma S.A.S., University of GenoaInventors: Alessandro Moretta, Mariella Della Chiesa, Pascale Andre, Laurent Gauthier, Francois Romagne, Peter Andreas Nicolai Reumert Wagtmann, Ivan Svendsen, Stefan Zahn, Anders Svensson, Matthias Thorolfsson, Soren Berg Padkaer, Kristian Kjaergaard, Pieter Johannes Louis Spee, Michael Wilken
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Publication number: 20130060073Abstract: A process and a plant for producing an olefin stream from a hydrocarbon mixture feed stream, wherein the olefin stream is depleted as regards its content of oxygen-containing organic compounds (oxygenates) as compared to the feed stream. The hydrocarbon mixture feed stream is charged to a separation column operated by a thermal separation process, for example to a distillation column, wherein a material stream enriched in oxygenates is withdrawn via a side outlet and removed from the process. The process according to the invention is particularly useful for processing the product streams obtained in the olefin synthesis by an OTO process.Type: ApplicationFiled: April 21, 2011Publication date: March 7, 2013Applicant: LURGI GMBHInventors: Hermann Bach, Thomas Renner, Martin Rothaemel, Michael Wilken
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Publication number: 20120208237Abstract: Compositions and methods for regulating an immune response in a subject are described. More particularly, described are human antibodies that regulate the activity of NK cells and allow a potentiation of NK cell cytotoxicity in mammalian subjects, and antibodies having antigen-binding properties similar to those of human monoclonal antibody 1-7F9 or 1-4F1. Described also are also fragments and derivatives of such antibodies, as well as pharmaceutical compositions comprising the same and their uses, particularly for use in therapy, to increase NK cell activity or cytotoxicity in subjects.Type: ApplicationFiled: January 11, 2012Publication date: August 16, 2012Applicants: Innate Pharma S.A.S, Novo-Nordisk A/S - Novo AlleInventors: Alessandro Moretta, Mariella Della Chiesa, Pascale Andre, Laurent Gauthier, Francois Romagné, Peter Andreas Nicolai Reumert Wagtmann, Ivan Svendsen, Stefan Zahn, Anders Svensson, Matthias Thórólfsson, Søren Berg Padkær, Kristian Kjaergaard, Pieter Spee, Michael Wilken
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Patent number: 8119775Abstract: Compositions and methods for regulating an immune response in a subject are described. More particularly, described are human antibodies that regulate the activity of NK cells and allow a potentiation of NK cell cytotoxicity in mammalian subjects, and antibodies having antigen-binding properties similar to those of human monoclonal antibody 1-7F9 or 1-4F1. Described also are also fragments and derivatives of such antibodies, as well as pharmaceutical compositions comprising the same and their uses, particularly for use in therapy, to increase NK cell activity or cytotoxicity in subjects.Type: GrantFiled: October 2, 2008Date of Patent: February 21, 2012Assignees: University of Genoa, Innate Pharma S.A.S., Novo Nordisk A/SInventors: Alessandro Moretta, Mariella Della Chiesa, Pascale Andre, Laurent Gauthier, Francois Romagné, Peter Andreas Nicolai Reumert Wagtmann, Ivan Svendsen, Stefan Zahn, Anders Svensson, Matthias Thórólfsson, Søren Berg Padkær, Kristian Kjaergaard, Pieter Spee, Michael Wilken
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Publication number: 20090081240Abstract: Compositions and methods for regulating an immune response in a subject are described. More particularly, described are human antibodies that regulate the activity of NK cells and allow a potentiation of NK cell cytotoxicity in mammalian subjects, and antibodies having antigen-binding properties similar to those of human monoclonal antibody 1-7F9 or 1-4F1. Described also are also fragments and derivatives of such antibodies, as well as pharmaceutical compositions comprising the same and their uses, particularly for use in therapy, to increase NK cell activity or cytotoxicity in subjects.Type: ApplicationFiled: October 2, 2008Publication date: March 26, 2009Applicants: Novo Nordisk A/S, Innate Pharma, University of GenoaInventors: Alessandro Moretta, Mariella Della Chiesa, Pascale Andre, Laurent Gauthier, Francois Romagne, Peter Andreas Nicolai Reumert Wagtmann, Ivan Svendsen, Stefan Zahn, Anders Svensson, Matthias Thorolfsson, Soren Berg Padkaer, Kristian Kjaergaard, Pieter Spee, Michael Wilken