Abstract: Provided is a process for producing pure methanol from carbon dioxide-rich synthesis gas, the process including the following steps: at least partially reacting the carbon dioxide rich synthesis gas in a methanol synthesis unit, discharging a liquid crude methanol stream from the methanol synthesis unit, introducing the liquid crude methanol stream into a flash tank, discharging from the flash tank a liquid depressurized crude methanol stream as a bottoms product and a gaseous overhead product stream having synthesis gas components, introducing the liquid depressurized crude methanol stream into a distillation apparatus having of a single distillation column, separating the crude methanol stream in the distillation column, discharging an overhead product stream via an overhead product outlet, discharging a bottoms product stream via the bottoms product outlet, and discharging a pure methanol product stream via a first side draw.

Abstract: A nozzle applies a sealant to a target area that includes a coupling member and an elongated seam. The nozzle includes a primary portion positionable in line with the coupling member in the target area, a first secondary portion on a first side of the primary portion, and a second secondary portion on a second side of the primary portion. The primary portion is in fluid communication with one or more material sources. The first secondary portion extends from the primary portion such that the first secondary portion is configured to extend over at least a segment of the elongated seam in the target area when the primary portion is positioned in line with the coupling member in the target area. The first secondary portion has a first height, and the second secondary portion has a second height less than the first height.

Abstract: A process and a plant for purifying a crude gas stream containing sulfur components and hydrocarbons by gas scrubbing using a scrubbing medium which is selective for sulfur components in an absorption column. Heavy hydrocarbons and heavy mercaptans are removed from the crude gas in a lower section of the absorption column and the resulting, loaded scrubbing medium stream is fed separately from the other loaded scrubbing medium streams to a hot regeneration column. A vapor stream enriched in water, hydrocarbons and sulfur components is obtained as overhead product from the hot regeneration column and this stream is cooled to below its dew point and is separated in a gas-liquid-liquid phase separation apparatus. The resulting, organic liquid phase contains heavy hydrocarbons and heavy mercaptans and can thus be discharged from the process or the plant, as a result of which accumulation thereof in the scrubbing medium is prevented.

Abstract: A process and a plant for purifying a crude gas stream containing sulfur components and hydrocarbons by gas scrubbing using a scrubbing medium which is selective for sulfur components in an absorption column. Heavy hydrocarbons and heavy mercaptans are removed from the crude gas in a lower section of the absorption column and the resulting, loaded scrubbing medium stream is fed separately from the other loaded scrubbing medium streams to a hot regeneration column. A vapor stream enriched in water, hydrocarbons and sulfur components is obtained as overhead product from the hot regeneration column and this stream is cooled to below its dew point and is separated in a gas-liquid-liquid phase separation apparatus. The resulting, organic liquid phase contains heavy hydrocarbons and heavy mercaptans and can thus be discharged from the process or the plant, as a result of which accumulation thereof in the scrubbing medium is prevented.

Abstract: An application system includes one or more flow control mechanisms controlling a flow path to a dispenser device, one or more position control mechanisms controlling a position of the dispenser device, and a memory device storing data associated with the flow control mechanisms, the position control mechanisms, one or more target areas, and computer-executable instructions. The computer-executable instructions may be executed to identify a target area, actuate the position control mechanisms to move the dispenser device toward the target area, actuate the flow control mechanisms to channel the sealant materials toward the dispenser device, dispense one or more first shots of the sealant materials onto the target area using the dispenser device for forming a dollop at the target area, and dispense one or more second shots of the sealant materials onto the target area using the dispenser device for forming a sealant layer that overlies the dollop.

Abstract: A nozzle applies a sealant to a target area that includes a coupling member and an elongated seam. The nozzle includes a primary portion positionable in line with the coupling member in the target area, a first secondary portion on a first side of the primary portion, and a second secondary portion on a second side of the primary portion. The primary portion is in fluid communication with one or more material sources. The first secondary portion extends from the primary portion such that the first secondary portion is configured to extend over at least a segment of the elongated seam in the target area when the primary portion is positioned in line with the coupling member in the target area. The first secondary portion has a first height, and the second secondary portion has a second height less than the first height.

Abstract: A method of applying a coating material to a vehicle that includes defining a plurality of application zones on the vehicle. The application zones include a low visibility zone, a medium visibility zone, and a high visibility zone. The method further includes applying the coating material to the application zones in a predetermined sequence such that a first portion of the coating material is applied to the low visibility zone, then a second portion is applied to the medium visibility zone, and then a third portion is applied to the high visibility zone. A first overlap region is defined between the low visibility zone and the high visibility zone and a second overlap region is defined between the medium visibility zone and the high visibility zone. The third portion of the coating material is applied before the coating material previously applied in the first and second overlap regions has set for a predefined duration.

Abstract: An application system includes one or more flow control mechanisms controlling a flow path to a dispenser device, one or more position control mechanisms controlling a position of the dispenser device, and a memory device storing data associated with the flow control mechanisms, the position control mechanisms, one or more target areas, and computer-executable instructions. The computer-executable instructions may be executed to identify a target area, actuate the position control mechanisms to move the dispenser device toward the target area, actuate the flow control mechanisms to channel the sealant materials toward the dispenser device, dispense one or more first shots of the sealant materials onto the target area using the dispenser device for forming a dollop at the target area, and dispense one or more second shots of the sealant materials onto the target area using the dispenser device for forming a sealant layer that overlies the dollop.

Abstract: A method of applying a coating material to a vehicle that includes defining a plurality of application zones on the vehicle. The application zones include a low visibility zone, a medium visibility zone, and a high visibility zone. The method further includes applying the coating material to the application zones in a predetermined sequence such that a first portion of the coating material is applied to the low visibility zone, then a second portion is applied to the medium visibility zone, and then a third portion is applied to the high visibility zone. A first overlap region is defined between the low visibility zone and the high visibility zone and a second overlap region is defined between the medium visibility zone and the high visibility zone. The third portion of the coating material is applied before the coating material previously applied in the first and second overlap regions has set for a predefined duration.

Abstract: A process and a plant for producing an olefin stream from a hydrocarbon mixture feed stream, wherein the olefin stream is depleted as regards its content of oxygen-containing organic compounds (oxygenates) as compared to the feed stream. The hydrocarbon mixture feed stream is charged to a separation column operated by a thermal separation process, for example to a distillation column, wherein a material stream enriched in oxygenates is withdrawn via a side outlet and removed from the process. The process according to the invention is particularly useful for processing the product streams obtained in the olefin synthesis by an OTO process.

Abstract: Compositions and methods for regulating an immune response in a subject are described. More particularly, described are human antibodies that regulate the activity of NK cells and allow a potentiation of NK cell cytotoxicity in mammalian subjects, and antibodies having antigen-binding properties similar to those of human monoclonal antibody 1-7F9 or 1-4F1. Described also are also fragments and derivatives of such antibodies, as well as pharmaceutical compositions comprising the same and their uses, particularly for use in therapy, to increase NK cell activity or cytotoxicity in subjects.

Abstract: Compositions and methods for regulating an immune response in a subject are described. More particularly, described are human antibodies that regulate the activity of NK cells and allow a potentiation of NK cell cytotoxicity in mammalian subjects, and antibodies having antigen-binding properties similar to those of human monoclonal antibody 1-7F9 or 1-4F1. Described also are also fragments and derivatives of such antibodies, as well as pharmaceutical compositions comprising the same and their uses, particularly for use in therapy, to increase NK cell activity or cytotoxicity in subjects.

Abstract: Compositions and methods for regulating an immune response in a subject are described. More particularly, described are human antibodies that regulate the activity of NK cells and allow a potentiation of NK cell cytotoxicity in mammalian subjects, and antibodies having antigen-binding properties similar to those of human monoclonal antibody 1-7F9 or 1-4F1. Described also are also fragments and derivatives of such antibodies, as well as pharmaceutical compositions comprising the same and their uses, particularly for use in therapy, to increase NK cell activity or cytotoxicity in subjects.

Abstract: A process and a plant for producing an olefin stream from a hydrocarbon mixture feed stream, wherein the olefin stream is depleted as regards its content of oxygen-containing organic compounds (oxygenates) as compared to the feed stream. The hydrocarbon mixture feed stream is charged to a separation column operated by a thermal separation process, for example to a distillation column, wherein a material stream enriched in oxygenates is withdrawn via a side outlet and removed from the process. The process according to the invention is particularly useful for processing the product streams obtained in the olefin synthesis by an OTO process.

Abstract: Compositions and methods for regulating an immune response in a subject are described. More particularly, described are human antibodies that regulate the activity of NK cells and allow a potentiation of NK cell cytotoxicity in mammalian subjects, and antibodies having antigen-binding properties similar to those of human monoclonal antibody 1-7F9 or 1-4F1. Described also are also fragments and derivatives of such antibodies, as well as pharmaceutical compositions comprising the same and their uses, particularly for use in therapy, to increase NK cell activity or cytotoxicity in subjects.

Abstract: Compositions and methods for regulating an immune response in a subject are described. More particularly, described are human antibodies that regulate the activity of NK cells and allow a potentiation of NK cell cytotoxicity in mammalian subjects, and antibodies having antigen-binding properties similar to those of human monoclonal antibody 1-7F9 or 1-4F1. Described also are also fragments and derivatives of such antibodies, as well as pharmaceutical compositions comprising the same and their uses, particularly for use in therapy, to increase NK cell activity or cytotoxicity in subjects.

Abstract: Compositions and methods for regulating an immune response in a subject are described. More particularly, described are human antibodies that regulate the activity of NK cells and allow a potentiation of NK cell cytotoxicity in mammalian subjects, and antibodies having antigen-binding properties similar to those of human monoclonal antibody 1-7F9 or 1-4F1. Described also are also fragments and derivatives of such antibodies, as well as pharmaceutical compositions comprising the same and their uses, particularly for use in therapy, to increase NK cell activity or cytotoxicity in subjects.

Abstract: A search query that includes a first spelling of a term is received. A second spelling of the term is generated. A first set of items that are associated with the first spelling of the term is accessed, and a second set of items that are associated with the second spelling of the term is accessed. A comparison is performed between the first set to the second set. A determination is made as to how to respond to the search query based, at least in part, on the comparison. The response may include a suggested search query that includes the second spelling of the term. The second spelling may be a suggested spelling correction or an alternative spelling. The response may include search results that are relevant to a search query that includes the first spelling of the term, the second spelling, or both the first and second spelling.