Patents by Inventor Michael Wilken

Michael Wilken has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12649706
    Abstract: Provided is a process for producing pure methanol from carbon dioxide-rich synthesis gas, the process including the following steps: at least partially reacting the carbon dioxide rich synthesis gas in a methanol synthesis unit, discharging a liquid crude methanol stream from the methanol synthesis unit, introducing the liquid crude methanol stream into a flash tank, discharging from the flash tank a liquid depressurized crude methanol stream as a bottoms product and a gaseous overhead product stream having synthesis gas components, introducing the liquid depressurized crude methanol stream into a distillation apparatus having of a single distillation column, separating the crude methanol stream in the distillation column, discharging an overhead product stream via an overhead product outlet, discharging a bottoms product stream via the bottoms product outlet, and discharging a pure methanol product stream via a first side draw.
    Type: Grant
    Filed: May 3, 2023
    Date of Patent: June 9, 2026
    Assignee: L'Air Liquide, Societe Anonyme Pour l'Etude et l'Exploitation des Procedes Georges Claude
    Inventors: Timm Schuhmann, Tobias Oelmann, Michael Wilken
  • Publication number: 20240208888
    Abstract: The invention relates to a process and to a plant for producing methanol from a synthesis gas having a hydrogen deficit. A fresh gas stream from a reformer unit which includes hydrogen and carbon oxides is combined with a hydrogen-containing stream from a hydrogen recovery stage. This affords a synthesis gas stream having a stoichiometry number SN, defined as SN=[n(H2)?n(CO2)]/[n(CO)+n(CO2)], of less than 2.0. The synthesis gas stream is combined with a residual gas stream and the synthesis gas stream and the residual gas stream are passed through a bed of a methanol synthesis catalyst at elevated pressure and elevated temperature to obtain a product stream having methanol and the residual gas stream, and the product stream is cooled to separate methanol from the residual gas stream.
    Type: Application
    Filed: April 26, 2022
    Publication date: June 27, 2024
    Inventors: Veronika GRONEMANN, Michael WILKEN, Tobias OELMANN
  • Publication number: 20230357111
    Abstract: Provided is a process for producing pure methanol from carbon dioxide-rich synthesis gas, the process including the following steps: at least partially reacting the carbon dioxide rich synthesis gas in a methanol synthesis unit, discharging a liquid crude methanol stream from the methanol synthesis unit, introducing the liquid crude methanol stream into a flash tank, discharging from the flash tank a liquid depressurized crude methanol stream as a bottoms product and a gaseous overhead product stream having synthesis gas components, introducing the liquid depressurized crude methanol stream into a distillation apparatus having of a single distillation column, separating the crude methanol stream in the distillation column, discharging an overhead product stream via an overhead product outlet, discharging a bottoms product stream via the bottoms product outlet, and discharging a pure methanol product stream via a first side draw.
    Type: Application
    Filed: May 3, 2023
    Publication date: November 9, 2023
    Inventors: Timm SCHUHMANN, Tobias OELMANN, Michael WILKEN
  • Patent number: 11578284
    Abstract: A process and a plant for purifying a crude gas stream containing sulfur components and hydrocarbons by gas scrubbing using a scrubbing medium which is selective for sulfur components in an absorption column. Heavy hydrocarbons and heavy mercaptans are removed from the crude gas in a lower section of the absorption column and the resulting, loaded scrubbing medium stream is fed separately from the other loaded scrubbing medium streams to a hot regeneration column. A vapor stream enriched in water, hydrocarbons and sulfur components is obtained as overhead product from the hot regeneration column and this stream is cooled to below its dew point and is separated in a gas-liquid-liquid phase separation apparatus. The resulting, organic liquid phase contains heavy hydrocarbons and heavy mercaptans and can thus be discharged from the process or the plant, as a result of which accumulation thereof in the scrubbing medium is prevented.
    Type: Grant
    Filed: June 29, 2021
    Date of Patent: February 14, 2023
    Assignee: L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude
    Inventors: Alfred Gubrinski, Dorit Rappold, Michael Wilken, Matthias Linicus
  • Publication number: 20210403822
    Abstract: A process and a plant for purifying a crude gas stream containing sulfur components and hydrocarbons by gas scrubbing using a scrubbing medium which is selective for sulfur components in an absorption column. Heavy hydrocarbons and heavy mercaptans are removed from the crude gas in a lower section of the absorption column and the resulting, loaded scrubbing medium stream is fed separately from the other loaded scrubbing medium streams to a hot regeneration column. A vapor stream enriched in water, hydrocarbons and sulfur components is obtained as overhead product from the hot regeneration column and this stream is cooled to below its dew point and is separated in a gas-liquid-liquid phase separation apparatus. The resulting, organic liquid phase contains heavy hydrocarbons and heavy mercaptans and can thus be discharged from the process or the plant, as a result of which accumulation thereof in the scrubbing medium is prevented.
    Type: Application
    Filed: June 29, 2021
    Publication date: December 30, 2021
    Inventors: Alfred Gubrinski, Dorit Rappold, Michael Wilken, Matthias Linicus
  • Patent number: 9505684
    Abstract: A process and a plant for producing an olefin stream from a hydrocarbon mixture feed stream, wherein the olefin stream is depleted as regards its content of oxygen-containing organic compounds (oxygenates) as compared to the feed stream. The hydrocarbon mixture feed stream is charged to a separation column operated by a thermal separation process, for example to a distillation column, wherein a material stream enriched in oxygenates is withdrawn via a side outlet and removed from the process. The process according to the invention is particularly useful for processing the product streams obtained in the olefin synthesis by an OTO process.
    Type: Grant
    Filed: April 21, 2011
    Date of Patent: November 29, 2016
    Assignee: AIR LIQUIDE GLOBAL E&C SOLUTIONS GERMANY GMBH
    Inventors: Hermann Bach, Thomas Renner, Martin Rothaemel, Michael Wilken
  • Publication number: 20150344576
    Abstract: Compositions and methods for regulating an immune response in a subject are described. More particularly, described are human antibodies that regulate the activity of NK cells and allow a potentiation of NK cell cytotoxicity in mammalian subjects, and antibodies having antigen-binding properties similar to those of human monoclonal antibody 1-7F9 or 1-4F1. Described also are also fragments and derivatives of such antibodies, as well as pharmaceutical compositions comprising the same and their uses, particularly for use in therapy, to increase NK cell activity or cytotoxicity in subjects.
    Type: Application
    Filed: August 18, 2015
    Publication date: December 3, 2015
    Inventors: Alessandro Moretta, Mariella Della Chiesa, Pascale Andre, Laurent Gauthier, Francois Romagne, Peter Andreas Nicolai Reumert Wagtmann, Ivan Svendsen, Stefan Zahn, Anders Svensson, Matthias Thorolfsson, Soren Berg Padkaer, Kristian Kjaergaard, Pieter Johannes Louis Spee, Michael Wilken
  • Publication number: 20150191547
    Abstract: Compositions and methods for regulating an immune response in a subject are described. More particularly, described are human antibodies that regulate the activity of NK cells and allow a potentiation of NK cell cytotoxicity in mammalian subjects, and antibodies having antigen-binding properties similar to those of human monoclonal antibody 1-7F9 or 1-4F1. Described also are also fragments and derivatives of such antibodies, as well as pharmaceutical compositions comprising the same and their uses, particularly for use in therapy, to increase NK cell activity or cytotoxicity in subjects.
    Type: Application
    Filed: March 16, 2015
    Publication date: July 9, 2015
    Inventors: Alessandro Moretta, Mariella Della Chiesa, Pascale Andre, Laurent Gauthier, Francois Romagne, Peter Andreas Nicolai Reumert Wagtmann, Ivan Svendsen, Stefan Zahn, Anders Svensson, Matthias Thorolfsson, Soren Berg Padkaer, Kristian Kjaergaard, Pieter Johannes Louis Spee, Michael Wilken
  • Patent number: 8981065
    Abstract: Compositions and methods for regulating an immune response in a subject are described. More particularly, described are human antibodies that regulate the activity of NK cells and allow a potentiation of NK cell cytotoxicity in mammalian subjects, and antibodies having antigen-binding properties similar to those of human monoclonal antibody 1-7F9 or 1-4F1. Described also are also fragments and derivatives of such antibodies, as well as pharmaceutical compositions comprising the same and their uses, particularly for use in therapy, to increase NK cell activity or cytotoxicity in subjects.
    Type: Grant
    Filed: July 8, 2013
    Date of Patent: March 17, 2015
    Assignees: Novo Nordisk A/S—Novo Alle, Innate Pharma S.A.S., University of Genoa
    Inventors: Alessandro Moretta, Mariella Della Chiesa, Pascale Andre, Laurent Gauthier, Francois Romagne, Peter Andreas Nicolai Reumert Wagtmann, Ivan Svendsen, Stefan Zahn, Anders Svensson, Matthias Thorolfsson, Soren Berg Padkaer, Kristian Kjaergaard, Pieter Johannes Louis Spee, Michael Wilken
  • Publication number: 20130060073
    Abstract: A process and a plant for producing an olefin stream from a hydrocarbon mixture feed stream, wherein the olefin stream is depleted as regards its content of oxygen-containing organic compounds (oxygenates) as compared to the feed stream. The hydrocarbon mixture feed stream is charged to a separation column operated by a thermal separation process, for example to a distillation column, wherein a material stream enriched in oxygenates is withdrawn via a side outlet and removed from the process. The process according to the invention is particularly useful for processing the product streams obtained in the olefin synthesis by an OTO process.
    Type: Application
    Filed: April 21, 2011
    Publication date: March 7, 2013
    Applicant: LURGI GMBH
    Inventors: Hermann Bach, Thomas Renner, Martin Rothaemel, Michael Wilken
  • Publication number: 20120208237
    Abstract: Compositions and methods for regulating an immune response in a subject are described. More particularly, described are human antibodies that regulate the activity of NK cells and allow a potentiation of NK cell cytotoxicity in mammalian subjects, and antibodies having antigen-binding properties similar to those of human monoclonal antibody 1-7F9 or 1-4F1. Described also are also fragments and derivatives of such antibodies, as well as pharmaceutical compositions comprising the same and their uses, particularly for use in therapy, to increase NK cell activity or cytotoxicity in subjects.
    Type: Application
    Filed: January 11, 2012
    Publication date: August 16, 2012
    Applicants: Innate Pharma S.A.S, Novo-Nordisk A/S - Novo Alle
    Inventors: Alessandro Moretta, Mariella Della Chiesa, Pascale Andre, Laurent Gauthier, Francois Romagné, Peter Andreas Nicolai Reumert Wagtmann, Ivan Svendsen, Stefan Zahn, Anders Svensson, Matthias Thórólfsson, Søren Berg Padkær, Kristian Kjaergaard, Pieter Spee, Michael Wilken
  • Patent number: 8119775
    Abstract: Compositions and methods for regulating an immune response in a subject are described. More particularly, described are human antibodies that regulate the activity of NK cells and allow a potentiation of NK cell cytotoxicity in mammalian subjects, and antibodies having antigen-binding properties similar to those of human monoclonal antibody 1-7F9 or 1-4F1. Described also are also fragments and derivatives of such antibodies, as well as pharmaceutical compositions comprising the same and their uses, particularly for use in therapy, to increase NK cell activity or cytotoxicity in subjects.
    Type: Grant
    Filed: October 2, 2008
    Date of Patent: February 21, 2012
    Assignees: University of Genoa, Innate Pharma S.A.S., Novo Nordisk A/S
    Inventors: Alessandro Moretta, Mariella Della Chiesa, Pascale Andre, Laurent Gauthier, Francois Romagné, Peter Andreas Nicolai Reumert Wagtmann, Ivan Svendsen, Stefan Zahn, Anders Svensson, Matthias Thórólfsson, Søren Berg Padkær, Kristian Kjaergaard, Pieter Spee, Michael Wilken
  • Publication number: 20090081240
    Abstract: Compositions and methods for regulating an immune response in a subject are described. More particularly, described are human antibodies that regulate the activity of NK cells and allow a potentiation of NK cell cytotoxicity in mammalian subjects, and antibodies having antigen-binding properties similar to those of human monoclonal antibody 1-7F9 or 1-4F1. Described also are also fragments and derivatives of such antibodies, as well as pharmaceutical compositions comprising the same and their uses, particularly for use in therapy, to increase NK cell activity or cytotoxicity in subjects.
    Type: Application
    Filed: October 2, 2008
    Publication date: March 26, 2009
    Applicants: Novo Nordisk A/S, Innate Pharma, University of Genoa
    Inventors: Alessandro Moretta, Mariella Della Chiesa, Pascale Andre, Laurent Gauthier, Francois Romagne, Peter Andreas Nicolai Reumert Wagtmann, Ivan Svendsen, Stefan Zahn, Anders Svensson, Matthias Thorolfsson, Soren Berg Padkaer, Kristian Kjaergaard, Pieter Spee, Michael Wilken