Patents by Inventor Michael Witten

Michael Witten has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • KRAS INHIBITORS
    Publication number: 20260069605
    Abstract: Disclosed are compounds of Formula (I), methods of using the compounds for inhibiting KRAS activity and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders associated with KRAS activity such as cancer.
    Type: Application
    Filed: September 11, 2025
    Publication date: March 12, 2026
    Inventors: Alexander Sokolsky, Yannick Boni, Gia Hoang, Bin Hu, Gencheng Li, Rocco Policarpo, III, Brandon Smith, Xiaozhao Wang, Michael Witten, Wenhao Zhang, Suman Chakrabarty
  • BICYCLIC AMINE CDK12 INHIBITORS
    Publication number: 20250353842
    Abstract: The present application provides bicyclic amines that are inhibitors of cyclin-dependent kinase 12 (CDK12), as well as pharmaceutical compositions thereof, and methods of treating cancer using the same
    Type: Application
    Filed: June 22, 2023
    Publication date: November 20, 2025
    Inventors: Evan Styduhar, Xin Li, Robert Swyka, Oleg Vechorkin, Anlai Wang, Michael Witten
  • BICYCLIC HETEROCYCLES AS FGFR INHIBITORS
    Publication number: 20250057852
    Abstract: The present invention relates to bicyclic heterocycles, and pharmaceutical compositions of the same, that are inhibitors of the FGFR enzyme and are useful in the treatment of FGFR-associated diseases such as cancer.
    Type: Application
    Filed: July 18, 2024
    Publication date: February 20, 2025
    Inventors: Oleg Vechorkin, Minh Nguyen, Chao Qi, Anlai Wang, Michael Witten, Yao Xu, Hai Fen Ye, Ke Zhang, Peng Zhao, Wenqing Yao
  • Bicyclic heterocycles as FGFR inhibitors
    Patent number: 12083124
    Abstract: The present invention relates to bicyclic heterocycles, and pharmaceutical compositions of the same, that are inhibitors of the FGFR enzyme and are useful in the treatment of FGFR-associated diseases such as cancer.
    Type: Grant
    Filed: January 26, 2023
    Date of Patent: September 10, 2024
    Assignee: Incyte Corporation
    Inventors: Oleg Vechorkin, Minh Nguyen, Chao Qi, Anlai Wang, Michael Witten, Yao Xu, Hai Fen Ye, Ke Zhang, Peng Zhao, Wenqing Yao
  • Bicyclic heterocycles as FGFR inhibitors
    Patent number: 12012409
    Abstract: The present disclosure relates to bicyclic heterocycles, and pharmaceutical compositions of the same, that are inhibitors of the FGFR enzyme and are useful in the treatment of FGFR-associated diseases such as cancer.
    Type: Grant
    Filed: January 14, 2021
    Date of Patent: June 18, 2024
    Assignee: Incyte Corporation
    Inventors: Jeremy Roach, Artem Shvartsbart, Michael Witten, Wenqing Yao
  • BICYCLIC HETEROCYCLES AS FGFR INHIBITORS
    Publication number: 20230338389
    Abstract: The present invention relates to bicyclic heterocycles, and pharmaceutical compositions of the same, that are inhibitors of the FGFR enzyme and are useful in the treatment of FGFR-associated diseases such as cancer.
    Type: Application
    Filed: January 26, 2023
    Publication date: October 26, 2023
    Inventors: Oleg Vechorkin, Minh Nguyen, Chao Qi, Anlai Wang, Michael Witten, Yao Xu, Hai Fen Ye, Ke Zhang, Peng Zhao, Wenqing Yao
  • Bicyclic heterocycles as FGFR inhibitors
    Patent number: 11607416
    Abstract: The present invention relates to bicyclic heterocycles, and pharmaceutical compositions of the same, that are inhibitors of the FGFR enzyme and are useful in the treatment of FGFR-associated diseases such as cancer.
    Type: Grant
    Filed: October 14, 2020
    Date of Patent: March 21, 2023
    Assignee: Incyte Corporation
    Inventors: Oleg Vechorkin, Minh Nguyen, Chao Qi, Anlai Wang, Michael Witten, Yao Xu, Hai Fen Ye, Ke Zhang, Peng Zhao, Wenqing Yao
  • BICYCLIC HETEROCYCLES AS FGFR INHIBITORS
    Publication number: 20210214366
    Abstract: The present disclosure relates to bicyclic heterocycles, and pharmaceutical compositions of the same, that are inhibitors of the FGFR enzyme and are useful in the treatment of FGFR-associated diseases such as cancer.
    Type: Application
    Filed: January 14, 2021
    Publication date: July 15, 2021
    Inventors: Jeremy Roach, Artem Shvartsbart, Michael Witten, Wenqing Yao
  • BICYCLIC HETEROCYCLES AS FGFR INHIBITORS
    Publication number: 20210106588
    Abstract: The present invention relates to bicyclic heterocycles, and pharmaceutical compositions of the same, that are inhibitors of the FGFR enzyme and are useful in the treatment of FGFR-associated diseases such as cancer.
    Type: Application
    Filed: October 14, 2020
    Publication date: April 15, 2021
    Inventors: Oleg Vechorkin, Minh Nguyen, Chao Qi, Anlai Wang, Michael Witten, Yao Xu, Hai Fen Ye, Ke Zhang, Peng Zhao, Wenqing Yao
  • Comfort slide
    Publication number: 20060021200
    Abstract: A one piece flat plastic embodiment that keeps both sections of a three-point seat belt together when buckled up. This embodiment causes the upper torso section of a three-point seat belt to change its angle and how it lays across the users shoulder when buckled up. The further away from the seat belt locking device it is placed will cause the torso section of the seat belt to be further away from the user's neck.
    Type: Application
    Filed: July 30, 2004
    Publication date: February 2, 2006
    Inventor: Michael Witten