Abstract: An air conditioner for an enclosure that can include a housing that partly defines an ambient air exchange cavity and a tub that further defines the ambient air exchange cavity and partly defines a cooling cavity. The tub can support a first heat exchanger within the ambient air exchange cavity, and a second heat exchanger and a fan within the cooling cavity. The second heat exchanger can be included in a coolant flow loop with the first heat exchanger and the fan can move air across the second heat exchanger and into the inlet of the enclosure. The second heat exchanger can be located above the fan. A fluid trap can be provided below the second heat exchanger and adjacent the fan to capture condensate from the second heat exchanger and can direct the condensate into the ambient air exchange cavity for disposal.

Abstract: The present disclosure relates to methods for preparing extracellular vesicles (EVs). In particular, the methods provided herein comprise contacting a sample, which comprises EVs and one or more impurities, with a depth filter, wherein the depth filter is selected from a LA media grade depth filter, a SP media grade depth filter, or both. In some aspects, the methods further comprise one or more chromatography steps. The methods enable preparation of EVs for therapeutic and diagnostic applications, and isolation and/or sub-fractionation of EVs with desired properties for specific use.

Abstract: Described are soles for a shoe, in particular for a sports shoe, with a midsole. The midsole includes a first sole region, which includes particle foam. The midsole further includes a deformation region within the midsole, wherein the deformation region has a volume greater than that of a single expanded particle and is positioned so that it allows a sideward deformation of the material of the first sole region under a pressure load on the sole.

Abstract: A computer system is provided that includes a storage system, at least one transceiver, and a processing system with at least one hardware processor. The storage system stores a first list pair. The transceiver receives electronic data messages that each include a respective data transaction request. The processing system determines how the new data transaction request should be processed based on which communication protocol was used to submit the request. Updates regarding the first list pair are sent out to non-party client computer systems using different communication protocols, where one is faster than the other, but the slower update includes private data therein.

Abstract: Provided herein are oral compositions comprising zolmitriptan, and methods of use thereof e.g., for the treatment of the symptoms of autism spectrum disorder, and the treatment of aggression in patients with dementia.

Abstract: Various well-perforating systems and methods are disclosed incorporating a self-shunting detonator. The detonator may include an electrically-conductive detonator body. A resistor initiator inside the detonator body includes first and second leads. A grounding element inside the detonator body couples the detonator body to the first lead. An electrically-conductive clip coupled to the second lead includes an arm biased to electrical contact with an external surface of the detonator body to shunt the detonator. The arm is moveable away from the detonator body to un-shunt the detonator, such as automatically in response to insertion into a detonator housing.

Abstract: Systems, methods, and devices described herein provide for operating a lighting fixture with a plurality of light sources at a target chromaticity with a target output spectral power distribution. The methods include multiplying a first spectral power distribution by a second spectral power distribution to determine a product spectral power distribution, multiplying the product spectral power distribution by an illuminant spectral power distribution to determine the target output spectral power distribution at the target chromaticity, and driving the plurality of light sources at intensities corresponding to the target output spectral power distribution.

Abstract: This system is a pneumatic actuation valve assembly that can include a frame; a timing spool housing; a timing spool carriage; a timing spool; a magnet configured to bias the timing spool in a forward position; a main spool and configured to travel toward a frame forward portion when a fluid is received into a mid-main spool pressure area wherein the main spool actuates a bolt carried by the frame and is configured to receive a projectile in an open position and chamber the projectile in a closed position; and, a bore defined in the timing spool configured to allow pressure in a rear main spool pressure area to escape through the bore releasing rearward pressure on the timing spool allowing the timing spool to travel from the rearward position to the forward position according to an attraction of the magnet.

Abstract: Described are soles for a shoe, in particular for a sports shoe, with a midsole. The midsole includes a first sole region, which includes particle foam. The midsole further includes a deformation region within the midsole, wherein the deformation region has a volume greater than that of a single expanded particle and is positioned so that it allows a sideward deformation of the material of the first sole region under a pressure load on the sole.

Abstract: A computer system is provided that includes a storage system, at least one transceiver, and a processing system with at least one hardware processor. The storage system stores a first list pair. The transceiver receives electronic data messages that each include a respective data transaction request. The processing system determines how the new data transaction request should be processed based on which communication protocol was used to submit the request. Updates regarding the first list pair are sent out to non-party client computer systems using different communication protocols, where one is faster than the other, but the slower update includes private data therein.

Abstract: Navigation and simulation systems and methods for minimally invasive therapy in which the navigation system imports a planning method using patient specific preoperative images. The navigation system uses intraoperative imaging during the medical procedure to update the preoperative images and provides images of tracked surgical tools along the surgical path prepared from the preoperative images.

Abstract: A method and system for azimuthal direction detection of a cable. The method may comprise disposing an electromagnetic logging tool into a wellbore, transmitting a primary electromagnetic field from the one or more transmitters, recording one or more secondary electromagnetic fields at the one or more receivers, and identifying a direction to the cable from the one or more secondary electromagnetic fields. The system may comprise one or more transmitters disposed on the electromagnetic logging tool and configured to transmit a primary electromagnetic field. The system may further comprise one or more receivers disposed on the electromagnetic logging tool and configured to record one or more secondary electromagnetic fields. Additionally, the system may further comprise an information handling system configured to identify a direction to an azimuthally localized reduction in metal of the conductor or increase in the metal of the conductor from the secondary electromagnetic fields.

Abstract: Systems and methods are provided in which local tissue diagnostic measurements are correlated with archival local tissue diagnostic data from prior tissue analyses to supplement diagnostic measurements with tissue analysis data from prior tissue analyses having similar local tissue diagnostic data. The tissue analysis data may include information such as pathology data, outcome data, and diagnosis data. The archived local tissue diagnostic data and the tissue analysis data may be stored in a database, and employed for a wide variety of methods, involving preoperative, intraoperative, and/or postoperative phases of a medical procedure. Methods and systems are also provided for displaying, on a medical image shown in a user interface, hyperlinked reference markers associated with tissue analyses, where the reference markers are shown at locations corresponding to local tissue analyses, and where associated diagnostic data and/or tissue analysis may be viewed by selecting a given reference marker.

Abstract: Using a machine learning model(s) for fraud reduction is described. A payment service computing platform may receive, from an electronic device, user data associated with a user, and dynamically determine an incentive(s) associated with the user based on the user data. The incentive(s) may be determined using a trained machine learning model(s) that is trained based on previously collected user data. The payment service computing platform can then cause a user interface to be displayed via a payment application executing on the electronic device, wherein the user interface presents an interactive element(s) for receiving the incentive(s) in exchange for the user referring at least one other user to a payment service.

Abstract: Improved soles and insoles for shoes, in particular sports shoes, are described. In an aspect, a sole for a shoe, in particular a sports shoe, with at least a first and a second surface region is provided. The first surface region comprises expanded thermoplastic polyurethane (“TPU”). The second surface region is free from expanded TPU.

Abstract: A photonics transceiver is described herein, wherein the photonics transceiver exhibits improved areal bandwidth density and improved energy per bit consumption relative to conventional photonics transceivers. The photonics transceiver achieves an areal bandwidth density of at least 5 Tbps/mm2 with an energy consumption of less than 500 fJ/bit (sum of energy consumed for both a transmitted bit and a received bit). The photonics transceiver is a multi-chip module, where chips in the multi-chip module are tightly integrated with one another. The multi-chip module includes light source, photodetector, photonics, and control/logic chips. The photonics chip includes transparent conducting oxide integrated optical modulators and multiplexers and demultiplexers based on MEMS-tunable optical ring resonators.

Abstract: Stillage solids concentration methods are disclosed wherein a solids concentration aid is added to a process stream mixture in a corn to ethanol process. The solids concentration aid may comprise a cationic polymer coagulant or flocculant or both, a starch based coagulant or flocculant or a biologically derived (i.e., plant or animal origin) coagulant or flocculant. Acrylamide/quaternary ammonium copolymers and homopolymeric polydiallyldimethyl ammonium chloride polymers are noteworthy examples of suitable solids concentration aids.

Abstract: A microelectromechanical systems (MEMS)-tunable optical ring resonator is described herein. The ring resonator includes a resonator ring and a tuner ring, along with one or more springs. The springs may be internal or external, i.e., either within or outside the areal footprint of the resonator ring and the tuner ring. The one or more springs are configured to displace the tuner ring from the resonator ring by a desired gap based upon a desired resonant wavelength of the resonator ring. Tuning is implemented by applying a voltage to the ring resonator, with motion of the tuner ring causing a corresponding change in the effective index of the resonator ring. As the ring resonator is essentially a capacitive device, it draws very little power once tuning is achieved.

Abstract: A system and method for dynamic validation, registration correction for surgical navigation during medical procedures involving confirmation of registration between previously registered virtual objects, in a common coordinate frame of a surgical navigation system and an operating room, and intra-operatively acquired imaging during the medical procedure in the common coordinate frame. The method involves displaying intra-operatively acquired imaging of the surgical field, containing the real objects corresponding to the previously registered virtual objects, with the real objects being tracked by a tracking system.