Abstract: A battery pack for an electrical device including a housing having a first housing portion defining a first compartment and a second housing portion defining a second compartment, a plurality of battery cells disposed within the first compartment and configured to supply power to the electrical device, a circuit board disposed within the first compartment and including a heat generating component, and a heat sink coupled to the second housing portion and disposed adjacent the heat generating component. The heat sink includes a first portion extending toward the heat generating component and disposed within the first compartment, and a second portion extending away from the heat generating component and disposed within the second compartment.

Abstract: Disclosed are macrocyclic peptide compounds or a salt thereof, which are useful as modulators of TNF?, and pharmaceutical compositions comprising such compounds. These compounds may be useful in treating cancers, inflammatory and autoimmune diseases.

Abstract: One or more controllers, after activation of a vehicle, may charge and discharge a traction battery according to power limits that are based on polarization voltages describing internal states of the traction battery and that are a function of polarization voltages present at a last deactivation of the vehicle and decay values having time constants that are based on a state of charge of the traction battery and a temperature associated with the traction battery.

Abstract: A susceptor assembly for supporting a crucible during a crystal growth process includes a susceptor base, a tubular sidewall connected to the susceptor base, and a removable sacrifice ring interposed between the susceptor base and the sidewall. Each of the susceptor base and the sidewall is formed of a carbon-containing material. The susceptor base has an annular wall and a shoulder extending radially outward from an outer surface of the annular wall. The sidewall has a first end that receives the annular wall to connect the sidewall to the susceptor base. The sacrifice ring has a first surface that faces the outer surface of the annular wall, a second surface that faces an interior surface of the sidewall, and a ledge extending outward from the second surface that engages the first end of the sidewall.

Abstract: A data management system (DMS) may receive an indication of a configuration for a quorum-based authorization (QAuth) policy that controls interactions between two or more users and a security cloud service of the DMS. The configuration may include a policy scope for the QAuth policy, protected actions that trigger the QAuth policy, and compute objects to which the QAuth policy is assigned. The DMS may receive an instruction to assign a set of role-based access control (RBAC) permissions associated with the QAuth policy to a first user. The DMS may receive a request to perform a protected action on at least one compute object to which the QAuth policy is assigned. In response to the request, the DMS may trigger a two-person rule (TPR) enforcement mechanism of the QAuth policy by requesting approval from the first user with the set of RBAC permissions.

Abstract: Integrated processes and facilities for providing recycled content hydrocarbon products (r-products) from mixed waste plastic are provided. Carbon dioxide capture and energy recovery from one or more process streams described herein increase energy efficiency and help reduce overall environmental impact while producing valuable final products from chemically recycled waste plastic.

Abstract: A process and system for recovering a recycle content carbon dioxide is provided that can lower the carbon footprint and global warming potential of a chemical recycling facility. More particularly, a pyrolysis gas from waste plastic pyrolysis may be treated in an absorber system to thereby form a recovered CO2 stream comprising recycle content carbon dioxide. Thus, the global warming potential of the chemical recycling facility may be optimized and lowered due to the carbon dioxide recovery process and system herein.

Abstract: A gas concentration determination system includes an acoustic sensor generating acoustic sensor data and a humidity sensor generating relative humidity data. A modified relative humidity is determined based at least in part on the acoustic sensor data and the relative humidity data. A gas concentration is determined using the modified relative humidity and the acoustic data. Using the modified relative humidity instead of the relative humidity data may reduce false positives in detecting gas leaks in HVAC systems, for example.

Abstract: Linker-drug compounds and antibody-drug conjugates that bind to human oncology targets are disclosed. The linker-drug compounds and antibody-drug conjugates comprise a splicing modulator drug moiety. The disclosure further relates to methods and compositions for use in the treatment of neoplastic disorders by administering the antibody-drug conjugates provided herein.

Abstract: An icemaker includes a casing that receives water from a water supply and is in thermal communication with an evaporator of a sealed system that chills the casing to freeze the water. An auger is mounted within the interior volume and is rotatable to scrape the ice from the casing and urge it through an extruder to form nugget ice. A BLDC motor is mechanically coupled to the auger to selectively rotate the auger. A controller determines a target speed of the auger based at least in part on the ice production parameter, and operates the BLDC motor to rotate the auger at the target speed. The BLDC motor with the speed-closed control loop can provide the constant speed and enough torque to prevent the ice maker from freezing. The controller can adjust the PWM and the voltage will be adjusted slightly, then the torque will be adjusted accordingly.

Abstract: The present disclosure relates generally to compounds, of Formula I: Also disclosed are pharmaceutical compositions comprising said compounds and methods of making said compounds. The compounds of the disclosure are useful in treating or preventing human immunodeficiency virus (HIV) infection.

Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a user equipment (UE) may receive downlink communications with a receive beam that is formed using a set of antenna elements. The UE may measure, in parallel with the receiving the downlink communications, a channel impulse response (CIR) for each antenna element of the set of antenna elements in a round-robin fashion. The UE may generate a second receive beam or a transmit beam based at least in part on the CIRs for the set of antenna elements. Numerous other aspects are described.

Abstract: A five-membered-fused six-membered compound, a preparation method, a pharmaceutical composition, and the use. The penta-fused hexa-heterocyclic compound is a compound represented by formula (II) or (III). The compound has an inhibition or/and degradation effect on IRAK4.

Abstract: The present disclosure relates generally to compounds, of Formula I: Also disclosed are pharmaceutical compositions comprising said compounds and methods of making said compounds. The compounds of the disclosure are useful in treating or preventing human immunodeficiency virus (HIV) infection.

Abstract: Provided are computing systems, methods, and platforms that rank text with pairwise ranking prompting using a generative sequence processing model. A prompt comprising a query and sets of text associated with candidate results can be generated. The generative sequence processing model can be prompted with the prompt and perform pairwise comparisons between the sets of text in the prompt based on the query in the prompt. An output can be generated that ranks the sets of text in response to the query.

Abstract: Recycle content pyoil is cracked in a cracker furnace to make olefins and the coil outlet temperature of the r-pyoil fed coils can be lowered by adding r-pyoil to the cracker feedstock, or alternatively, the coil outlet temperature of the r-pyoil fed tubes can rise if the mass flow rates of the combined cracker stream containing r-pyoil are kept the same or lowered. Further, increasing the hydrocarbon mass flow rate by addition of r-pyoil can be achieved to also increase the output of ethylene and propylene in the cracker effluent. The cracker furnace can accept ethane and/or propane feedstocks in vapor form along with a liquid and/or vapor feed of r-pyoil.

Abstract: The invention provides flow batteries and methods of using flow batteries including long-lived redox-active molecules with low redox potential.

Abstract: Compounds for use in treating or preventing human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following formula (I) including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, R2, L, W1, W2, X, Y, and Z are as defined herein. Methods associated with the preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.

Abstract: The invention provides a novel class of therapeutic agents that are safe and effective TYK2 inhibitors and pharmaceutical compositions of these compounds and methods of preparation and use thereof against various TYK2-mediated diseases and disorders.

Abstract: Disclosed herein are systems and methods for electrically modulating tissue. Systems can include a current generator; at least one implantable working electrode, the at least one implantable working electrode configured to be in electrical communication with the current generator; at least one indifferent electrode; and a controller configured to signal the current generator to: generate a set of currents with a set of initial polarities to be delivered to the working electrodes; and wherein the at least one indifferent electrode absorbs a bias current which is equal in magnitude and opposite in polarity to a summation of the set of currents.