Patents by Inventor Michael Y. Torgov

Michael Y. Torgov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dosage Unit Form(s) Comprising BTS and BTS(OMe) For Use In Boron Neutron Capture Therapy and Methods Thereof
    Publication number: 20240092808
    Abstract: Borylated Amino Acid compositions comprising tyrosine derivatives BTS and BTS(OMe) and novel methods of making BTS and BTS(OMe) are disclosed herein. Consequently, the BTS and/or BTS(OMe) can be scaled up to commercial scale and administered to patients as a Neutron Capture Agent and provide a method of treating cancer, immunological disorders, and other disease by utilizing a Neutron Capture Therapy modality.
    Type: Application
    Filed: November 15, 2023
    Publication date: March 21, 2024
    Inventors: Michael Y. Torgov, Tloga J. Martin
  • Borylated amino acid compositions comprising BTS and BTS(OMe) for use in boron neutron capture therapy and methods thereof
    Patent number: 11884688
    Abstract: Borylated Amino Acid compositions comprising tyrosine derivatives BTS and BTS(OMe) and novel methods of making BTS and BTS(OMe) are disclosed herein. Consequently, the BTS and/or BTS(OMe) can be scaled up to commercial scale and administered to patients as a Neutron Capture Agent and provide a method of treating cancer, immunological disorders, and other disease by utilizing a Neutron Capture Therapy modality.
    Type: Grant
    Filed: August 1, 2022
    Date of Patent: January 30, 2024
    Assignee: TAE Life Sciences, LLC
    Inventors: Michael Y. Torgov, Tioga J. Martin
  • Borylated Di-Peptide Amino Acid compositions for use in Boron Neutron Capture Therapy and methods thereof
    Publication number: 20230357312
    Abstract: Borylated Di-Peptide Amino Acid (“Bdi-AA”) compositions and Di-Peptide Amino Acid (di-AA) compositions and methods of making Bdi-AAs and di-AAs are disclosed herein. Consequently, the Bdi-AAs and di-AAs can be administered to patients as a Neutron Capture Agent and provide a method of treating cancer, immunological disorders, and other disease by utilizing a Neutron Capture Therapy modality.
    Type: Application
    Filed: December 16, 2022
    Publication date: November 9, 2023
    Inventors: Michael Y. Torgov, Tioga J. Martin, Arthur B. Raitano, Jason C. Quintana, Kendall Morrison
  • Borylated amino acid compositions for use in boron neutron capture therapy and methods thereof
    Publication number: 20230295190
    Abstract: Borylated Amino Acid (“BAA”) compositions and methods of making BAAs are disclosed herein. Consequently, the BAAs can be administered to patients as a Neutron Capture Agent and provide a method of treating cancer, immunological disorders and other disease by utilizing a Neutron Capture Therapy modality.
    Type: Application
    Filed: June 9, 2022
    Publication date: September 21, 2023
    Inventors: Michael Y. Torgov, Tioga J. Martin, Arthur B. Raitano
  • Borylated Amino Acid Compositions Comprising BTS and BTS(OMe) For Use in Boron Neutron Capture Treapy and Methods Thereof
    Publication number: 20230271984
    Abstract: Borylated Amino Acid compositions comprising tyrosine derivatives BTS and BTS(OMe) and novel methods of making BTS and BTS(OMe) are disclosed herein. Consequently, the BTS and/or BTS(OMe) can be scaled up to commercial scale and administered to patients as a Neutron Capture Agent and provide a method of treating cancer, immunological disorders, and other disease by utilizing a Neutron Capture Therapy modality.
    Type: Application
    Filed: August 1, 2022
    Publication date: August 31, 2023
    Inventors: Michael Y. Torgov, Tioga J. Martin
  • Borylated amino acid compositions for use in boron neutron capture therapy and methods thereof
    Patent number: 11566031
    Abstract: Borylated Amino Acid (“BAA”) compositions and methods of making BAAs are disclosed herein. Consequently, the BAAs can be administered to patients as a Neutron Capture Agent and provide a method of treating cancer, immunological disorders and other disease by utilizing a Neutron Capture Therapy modality.
    Type: Grant
    Filed: March 4, 2020
    Date of Patent: January 31, 2023
    Assignee: TAE Life Sciences, LLC
    Inventors: Michael Y. Torgov, Tioga J. Martin, Arthur B. Raitano
  • Boron enriched linker (“BEL”) compositions for boron neutron capture therapy and methods thereof
    Patent number: 11219689
    Abstract: Boron Enriched Linker (“BEL”) compositions and methods of making BELs are disclosed herein. Consequently, the BELs can be conjugated to antibodies or antibody fragments to create Antibody Boron Conjugates (“ABCs”) to provide a method of treating cancer, immunological disorders and other disease by utilizing a Neutron Capture Therapy modality.
    Type: Grant
    Filed: October 10, 2019
    Date of Patent: January 11, 2022
    Assignee: TAE Life Sciences, LLC
    Inventors: Michael Y. Torgov, Tioga J. Martin
  • Borylated amino acid compositions for use in boron neutron capture therapy and methods thereof
    Publication number: 20200283456
    Abstract: Borylated Amino Acid (“BAA”) compositions and methods of making BAAs are disclosed herein. Consequently, the BAAs can be administered to patients as a Neutron Capture Agent and provide a method of treating cancer, immunological disorders and other disease by utilizing a Neutron Capture Therapy modality.
    Type: Application
    Filed: March 4, 2020
    Publication date: September 10, 2020
    Inventors: Michael Y. Torgov, Tioga J. Martin, Arthur B. Raitano
  • Boron Enriched Linker ("BEL") compositions for boron neutron capture therapy and methods thereof
    Publication number: 20200114013
    Abstract: Boron Enriched Linker (“BEL”) compositions and methods of making BELs are disclosed herein. Consequently, the BELs can be conjugated to antibodies or antibody fragments to create Antibody Boron Conjugates (“ABCs”) to provide a method of treating cancer, immunological disorders and other disease by utilizing a Neutron Capture Therapy modality.
    Type: Application
    Filed: October 10, 2019
    Publication date: April 16, 2020
    Inventors: Michael Y. Torgov, Tioga J. Martin